Karen E. Lasser MD, MPH

Professor, General Internal Medicine

Professor, Community Health Sciences

801 Massachusetts Ave | (617) 414-6688
Karen Lasser

General Internal Medicine


Clinical Addiction Research and Education Unit

Evans Center for Interdisciplinary Biomedical Research


Dr. Lasser is a primary care internist, certified by the American Board of Internal Medicine, and a health services researcher. She is a Senior Editor at JAMA.

Her primary areas of expertise and research are quality of care, interventions to reduce health disparities, health policy, smoking cessation, and primary care practice-based research.

She is the author of over 80 peer-reviewed publications, was the former Director of Ambulatory Quality Improvement for the Department of Medicine at Cambridge Health Alliance/Harvard Medical School, and has held several quality leadership roles at Boston Medical Center. Her research has been supported by NIDA, NHLBI, AHRQ, CDC, and the American Cancer Society.

Other Positions


Medicine, MD, Cornell University Medical College

Clinical Evaluation/Research, MPH, Harvard School of Public Health

History, AB, Harvard University


Published on 2/10/2024

Cole MB, Strackman BW, Lasser KE, Lin MY, Paasche-Orlow MK, Hanchate AD. Medicaid Expansion and Preventable Emergency Department Use by Race/Ethnicity. Am J Prev Med. 2024 Jun; 66(6):989-998. PMID: 38342480.

Published on 1/16/2024

Taylor JL, Lasser KE. Intranasal Naloxone for Opioid Overdose. JAMA. 2024 Jan 16; 331(3):250-251. PMID: 38127361.

Published on 1/3/2024

Rose SW, Strackman BW, Gilbert ON, Lasser KE, Paasche-Orlow MK, Lin MY, Saylor G, Hanchate AD. Disparities by Sex, Race, and Ethnicity in Use of Left Ventricular Assist Devices and Heart Transplants Among Patients With Heart Failure With Reduced Ejection Fraction. J Am Heart Assoc. 2024 Jan 16; 13(2):e031021. PMID: 38166429.

Published on 11/18/2023

Liebschutz JM, Subramaniam GA, Stone R, Appleton N, Gelberg L, Lovejoy TI, Bunting AM, Cleland CM, Lasser KE, Beers D, Abrams C, McCormack J, Potter GE, Case A, Revoredo L, Jelstrom EM, Kline MM, Wu LT, McNeely J. Subthreshold opioid use disorder prevention (STOP) trial: a cluster randomized clinical trial: study design and methods. Addict Sci Clin Pract. 2023 Nov 18; 18(1):70. PMID: 37980494.

Published on 8/10/2023

Hanchate AD, Abdelfattah L, Lin MY, Lasser KE, Paasche-Orlow MK. Affordable Care Act Medicaid Expansion was Associated With Reductions in the Proportion of Hospitalizations That are Potentially Preventable Among Hispanic and White Adults. Med Care. 2023 Oct 01; 61(10):627-635. PMID: 37582292.

Published on 8/4/2023

Borden CG, Ashe EM, Buitron de la Vega P, Gast V, Saint-Phard T, Brody-Fialkin J, Power J, Wang N, Lasser KE. A novel pharmacy liaison program to address health-related social needs at an urban safety-net hospital. Am J Health Syst Pharm. 2023 Aug 04; 80(16):1071-1081. PMID: 37210728.

Published on 7/29/2023

Stulac SN, Costello E, Baker J, Elansary M, Reed K, Lasser KE. High Engagement in Care in a Pediatric Medical Home for Children Impacted By Parental Substance Use. Clin Pediatr (Phila). 2024 Jun; 63(6):769-773. PMID: 37515533.

Published on 5/29/2023

Shusterman S, Villarreal-Calderon R, Gunawan A, Gallardo Foreman A, O'Donnell C, Wakeman C, Javeed H, Keteyian J, Howard J, Bulekova K, de Silva S, Campbell T, Lasser K, Kathuria H. A Financial Incentives Program to Promote Smoking Cessation Among Recently Hospitalized Individuals: Feasibility and Acceptability Study. JMIR Form Res. 2023 May 29; 7:e44979. PMID: 37247216.

Published on 5/18/2023

Hanchate AD, Strackman BW, Lin M, Paasche-Orlow MK, Lasser KE, Cole MB. Medicaid expansion associated with no change in emergency department use across racial and ethnic groups. Health Serv Res. 2023 Oct; 58(5):1014-1023. PMID: 37202905.

Published on 1/3/2023

Buitron de la Vega P, Ashe EM, Xuan Z, Gast V, Saint-Phard T, Brody-Fialkin J, Okonkwo F, Power J, Wang N, Lyons C, Silverstein M, Lasser KE. A Pharmacy Liaison-Patient Navigation Intervention to Reduce Inpatient and Emergency Department Utilization Among Primary Care Patients in a Medicaid Accountable Care Organization: A Nonrandomized Controlled Trial. JAMA Netw Open. 2023 Jan 03; 6(1):e2250004. PMID: 36622674.

View full list of 101 publications.