Kalpana Gupta MD

Professor, Infectious Diseases

1400 VFW Parkway | (857) 203-5086
Kalpana Gupta

Infectious Diseases


Dr. Gupta is Chief, Section of Infectious Diseases at the Veterans Administration Boston Healthcare System, and Professor of Medicine at Boston University School of Medicine. Her primary research focus over the past decade has been on optimizing treatment regimens and prevention strategies for urinary tract infections (UTIs) in women. She is Chair of the IDSA UTI guideline update committee. She is currently PI of a multi-site NIH-funded randomized controlled trial of cranberry juice cocktail to prevent recurrent UTI in women and just completed a randomized trial of short course nitrofurantoin for treatment of acute cystitis in women. As a natural progression of her work on antimicrobial resistance in community-acquired UTIs, she is now embarking on a new research area, namely the evaluation of the prevalence and molecular epidemiology of MRSA infections in the veteran population.


MD, Stony Brook University, 1991

Epidemiology, MPH, University of Washington School of Public Health, 1998

English, BA, Stony Brook University, 1987


Published on 8/31/2022

Claeys KC, Trautner BW, Leekha S, Coffey KC, Crnich CJ, Diekema DJ, Fakih MG, Goetz MB, Gupta K, Jones MM, Leykum L, Liang SY, Pineles L, Pleiss A, Spivak ES, Suda KJ, Taylor JM, Rhee C, Morgan DJ. Optimal Urine Culture Diagnostic Stewardship Practice-Results from an Expert Modified-Delphi Procedure. Clin Infect Dis. 2022 Aug 31; 75(3):382-389. PMID: 34849637.

Published on 6/1/2022

Stern RA, Charness ME, Gupta K, Koutrakis P, Linsenmeyer K, Madjarov R, Martins MAG, Lemos B, Dowd SE, Garshick E. Concordance of SARS-CoV-2 RNA in Aerosols From a Nurses Station and in Nurses and Patients During a Hospital Ward Outbreak. JAMA Netw Open. 2022 Jun 01; 5(6):e2216176. PMID: 35675074.

Published on 4/7/2022

Johnson S, Gerding DN, Li X, Reda DJ, Donskey CJ, Gupta K, Goetz MB, Climo MW, Gordin FM, Ringer R, Johnson N, Johnson M, Calais LA, Goldberg AM, Ge L, Haegerich T. Defining optimal treatment for recurrent Clostridioides difficile infection (OpTION study): A randomized, double-blind comparison of three antibiotic regimens for patients with a first or second recurrence. Contemp Clin Trials. 2022 May; 116:106756. PMID: 35398532.

Published on 12/2/2021

Dipp Ramos R, O'Brien WJ, Gupta K, Itani KMF. Events, care, and outcomes after hernia mesh explantation for infection. Am J Surg. 2022 Jul; 224(1 Pt A):174-176. PMID: 34876254.

Published on 11/10/2021

Linsenmeyer K, Gupta K, Charness ME. Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant. N Engl J Med. 2021 12 16; 385(25):e92. PMID: 34758248.

Published on 11/1/2021

Linsenmeyer K, Charness ME, O'Brien WJ, Strymish J, Doshi SJ, Ljaamo SK, Gupta K. Vaccination Status and the Detection of SARS-CoV-2 Infection in Health Care Personnel Under Surveillance in Long-term Residential Facilities. JAMA Netw Open. 2021 11 01; 4(11):e2134229. PMID: 34757413.

Published on 10/7/2021

O'Brien WJ, Dipp Ramos R, Gupta K, Itani KMF. Risk of Hernia Mesh Explantation following Early Versus Late Onset Skin and Soft Tissue Infection. Ann Surg Open. 2021 Dec; 2(4):e098. PMID: 34957470.

Published on 9/17/2021

Cho K, Keithly SC, Kurgansky KE, Madenci AL, Gerlovin H, Marucci-Wellman H, Doubleday A, Thomas ER, Park Y, Ho YL, Sugimoto JD, Moore KP, Peterson AC, Hoag C, Gupta K, Jeans K, Klote M, Ramoni R, Huang GD, Casas JP, Gagnon DR, HernĂ¡n MA, Smith NL, Gaziano JM. Early Convalescent Plasma Therapy and Mortality Among US Veterans Hospitalized With Nonsevere COVID-19: An Observational Analysis Emulating a Target Trial. J Infect Dis. 2021 09 17; 224(6):967-975. PMID: 34153099.

Published on 8/12/2021

Dipp Ramos R, O'Brien WJ, Gupta K, Itani KMF. Re-Infection after Explantation of Infected Hernia Mesh: Are the Same Micro-Organisms Involved? Surg Infect (Larchmt). 2021 Dec; 22(10):1077-1080. PMID: 34388028.

Published on 6/1/2021

Gupta K, O'Brien WJ, Bellino P, Linsenmeyer K, Doshi SJ, Sprague RS, Charness ME. Incidence of SARS-CoV-2 Infection in Health Care Workers After a Single Dose of mRNA-1273 Vaccine. JAMA Netw Open. 2021 06 01; 4(6):e2116416. PMID: 34132795.

View full list of 135 publications.