Jonathan S. Williams MD

Adjunct Assistant Professor, Endocrinology, Diabetes, Nutrition & Weight Management

Associate Professor

72 E. Concord Street
Jonathan S. Williams

Endocrinology, Diabetes, Nutrition & Weight Management


Dr. Williams is Associate Professor of Medicine at Harvard Medical School and practicing endocrinologist at Brigham and Women's Hospital and the Boston VA Healthcare System. He directs the Cardiometabolic Human Genetics Research Program, which houses the HyperPath and HyperPath2 cohorts established over 20 years ago as a multinational program to decipher the genetic and mechanistic underpinnings of complex heritable diseases. His administrative roles include IRB Chair (MassGeneral Brigham), Co-Director Clinical and Translational Research Academy (Harvard Medical School), and Lead Medical Research Officer, Center for Clinical Investigations (Brigham and Women's Hospital).

Other Positions


Medicine, MD, Hahnemann University

Medical Sciences & Management, MMS/MMSc, Harvard University

Microbiology, BS, Brigham Young University


Published on 3/18/2024

Aljaibeji H, Heydarpour M, Stanton AM, Williams JS, Pojoga LH, Romero JR, Williams GH. Role of Raptor Gene Variants in Hypertension: Influence on Blood Pressure Independent of Salt Intake in White Population. Hypertension. 2024 Mar 18. PMID: 38497230.

Published on 3/4/2024

Heydarpour M, Parksook WW, Pojoga LH, Williams GH, Williams JS. Mineralocorticoid receptor and aldosterone: Interaction between NR3C2 genetic variants, sex and age in a mixed cohort. J Clin Endocrinol Metab. 2024 Mar 04. PMID: 38437868.

Published on 11/29/2023

Gholami SK, Heydarpour M, Williams JS, Pojoga LH, Adler GK, Williams GH, Romero JR. Striatin Gene Variants Are Associated With Salt Sensitivity of Blood Pressure by Mechanisms That Differ in Women and Men. Hypertension. 2024 Feb; 81(2):330-339. PMID: 38018471.

Published on 10/17/2023

Stanton AM, Heydarpour M, Williams JS, Williams GH, Adler GK. CACNA1D Gene Polymorphisms Associate With Increased Blood Pressure and Salt Sensitivity of Blood Pressure in White Individuals. Hypertension. 2023 Dec; 80(12):2665-2673. PMID: 37846579.

Published on 9/18/2023

Zitting KM, Isherwood CM, Yuan RK, Wang W, Vujovic N, Münch M, Cain SW, Williams JS, Buxton OM, Czeisler CA, Duffy JF. Eating during the biological night is associated with nausea. Sleep Health. 2023 Sep 18. PMID: 37730474.

Published on 9/16/2023

Burton Murray H, Ljótsson B, Healy B, Van Oudenhove L, Williams JS, Keefer L, Lawson EA, Kuo B, Thomas JJ. Brief cognitive-behavioral treatment for avoidant/restrictive food intake disorder in the context of functional dyspepsia: Study protocol for a feasibility randomized controlled trial. Contemp Clin Trials. 2023 Nov; 134:107336. PMID: 37722485.

Published on 3/20/2023

Heydarpour M, Parksook WW, Hopkins PN, Pojoga LH, Williams GH, Williams JS. A candidate locus in the renalase gene and susceptibility to blood pressure responses to the dietary salt. J Hypertens. 2023 May 01; 41(5):723-732. PMID: 36789764.

Published on 2/6/2023

Katayama IA, Huang Y, Garza AE, Brooks DL, Williams JS, Nascimento MM, Heimann JC, Pojoga LH. Longitudinal changes in blood pressure are preceded by changes in albuminuria and accelerated by increasing dietary sodium intake. Exp Gerontol. 2023 Mar; 173:112114. PMID: 36738979.

Published on 12/12/2022

Tan YJD, Brooks DL, Wong KYH, Huang Y, Romero JR, Williams JS, Pojoga LH. Lysine-specific demethylase 1 deficiency modifies aldosterone synthesis in a sex-specific manner. J Endocrinol. 2023 Jan 01; 256(1). PMID: 36327153.

Published on 7/11/2022

Xin Q, Yuan RK, Zitting KM, Wang W, Purcell SM, Vujovic N, Ronda JM, Quan SF, Williams JS, Buxton OM, Duffy JF, Czeisler CA. Impact of chronic sleep restriction on sleep continuity, sleep structure, and neurobehavioral performance. Sleep. 2022 Jul 11; 45(7). PMID: 35218665.

View full list of 89 publications.