Joanne M. Murabito MD

Professor, General Internal Medicine

73 Mt Wayte Ave | (508) 935-3461
Joanne Murabito
Sections

General Internal Medicine

Centers

Framingham Heart Study

Evans Center for Interdisciplinary Biomedical Research

Biography

Dr. Murabito is a Professor of Medicine at Chobanian and Avedisian School of Medicine and Co-PI at the Framingham Heart Study. Dr Murabito’s area of expertise is in epidemiology and genetic epidemiology. Her current research focuses on identifying the determinants of healthy aging and longevity and reproductive aging in the community including the investigation of genetic and genomic factors. She leads highly productive multidisciplinary international consortia including the Cohorts for Heart and Aging Research in Genomics Epidemiology (CHARGE) Aging and Longevity working group and the ReproGen Consortium. The Consortia bring together scientists interested in aging, longevity, and reproductive aging (menarche, menopause) and the relation of these traits to health outcomes and gene discovery.
Dr Murabito is also leading the introduction of mobile health into the Framingham Heart Study. She participated in an embedded physical activity trial using a smartphone app or activity tracker and would like to explore use of mHealth in older adults to improve health and function
Dr. Murabito continues to practice primary care at Boston Medical Center.

Education

MD, Mount Sinai School of Medicine

ScM, Harvard University

BA, University of Rochester

Publications

Published on 1/13/2025

Jakubek YA, Ma X, Stilp AM, Yu F, Bacon J, Wong JW, Aguet F, Ardlie K, Arnett DK, Barnes K, Bis JC, Blackwell T, Becker LC, Boerwinkle E, Bowler RP, Budoff MJ, Carson AP, Chen J, Cho MH, Coresh J, Cox NJ, de Vries PS, DeMeo DL, Fardo DW, Fornage M, Guo X, Hall ME, Heard-Costa N, Hidalgo B, Irvin MR, Johnson AD, Jorgenson E, Kenny EE, Kessler MD, Levy D, Li Y, Lima JAC, Liu Y, Locke AE, Loos RJF, Machiela MJ, Mathias RA, Mitchell BD, Murabito JM, Mychaleckyj JC, North KE, Orchard P, Parker SCJ, Pershad Y, Peyser PA, Pratte KA, Psaty BM, Raffield LM, Redline S, Rich SS, Rotter JI, Shah SJ, Smith JA, Smith AP, Smith A, Taub MA, Tiwari HK, Tracy R, Tuftin B, Bick AG, Sankaran VG, Reiner AP, Scheet P, Auer PL. Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood. Am J Hum Genet. 2025 Feb 06; 112(2):276-290. PMID: 39809269.

Published on 12/31/2024

Rong J, Pathiravasan CH, Zhang Y, Faro JM, Wang X, Schramm E, Borrelli B, Benjamin EJ, Liu C, Murabito JM. Baseline Smartphone App Survey Return in the Electronic Framingham Heart Study Offspring and Omni 1 Study: eCohort Study. JMIR Aging. 2024 Dec 31; 7:e64636. PMID: 39740111.

Published on 12/6/2024

Liu C, Joehanes R, Ma J, Xie J, Yang J, Wang M, Huan T, Hwang SJ, Wen J, Sun Q, Cumhur DY, Heard-Costa NL, Orchard P, Carson AP, Raffield LM, Reiner A, Li Y, O'Connor G, Murabito JM, Munson P, Levy D. Integrating Whole Genome and Transcriptome Sequencing to Characterize the Genetic Architecture of Isoform Variation and its Implications for Health and Disease. medRxiv. 2024 Dec 06. PMID: 39677465.

Published on 11/22/2024

Chen J, Murabito JM, Lunetta KL. ONDSA: a testing framework based on Gaussian graphical models for differential and similarity analysis of multiple omics networks. Brief Bioinform. 2024 Nov 22; 26(1). PMID: 39581869.

Published on 11/20/2024

Carbonneau M, Li Y, Qu Y, Zheng Y, Wood AC, Wang M, Liu C, Huan T, Joehanes R, Guo X, Yao J, Taylor KD, Tracy RP, Peter D, Liu Y, Johnson WC, Post WS, Blackwell T, Rotter JI, Rich SS, Redline S, Fornage M, Wang J, Ning H, Hou L, Lloyd-Jones D, Ferrier K, Min YI, Carson AP, Raffield LM, Teumer A, Grabe HJ, Völzke H, Nauck M, Dörr M, Domingo-Relloso A, Fretts A, Tellez-Plaza M, Cole S, Navas-Acien A, Wang M, Murabito JM, Heard-Costa NL, Prescott B, Xanthakis V, Mozaffarian D, Levy D, Ma J. DNA Methylation Signatures of Cardiovascular Health Provide Insights into Diseases. medRxiv. 2024 Nov 20. PMID: 39606375.

Published on 11/11/2024

Ramirez MF, Pan AS, Parekh JK, Owunna N, Courchesne P, Larson MG, Levy D, Murabito JM, Ho JE, Lau ES. Sex Differences in Protein Biomarkers and Measures of Fat Distribution. J Am Heart Assoc. 2024 Nov 19; 13(22):e000223. PMID: 39526334.

Published on 11/1/2024

Yao S, Boudreau RM, Galvin A, Murabito JM, Honig LS, Perls TT, Christensen K, Newman AB. All-Cause Mortality and Cause-Specific Death in U.S. Long-Lived Siblings: Data From the Long Life Family Study. J Gerontol A Biol Sci Med Sci. 2024 Nov 01; 79(11). PMID: 39086360.

Published on 10/3/2024

Hawkes G, Beaumont RN, Li Z, Mandla R, Li X, Albert CM, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Boerwinkle E, Brody JA, Carson AP, Chami N, Chen YI, Chung MK, Curran JE, Darbar D, Ellinor PT, Fornage M, Gordeuk VR, Guo X, He J, Hwu CM, Kalyani RR, Kaplan R, Kardia SLR, Kooperberg C, Loos RJF, Lubitz SA, Minster RL, Naseri T, Viali S, Mitchell BD, Murabito JM, Palmer ND, Psaty BM, Redline S, Shoemaker MB, Silverman EK, Telen MJ, Weiss ST, Yanek LR, Zhou H, Liu CT, North KE, Justice AE, Locke JM, Owens N, Murray A, Patel K, Frayling TM, Wright CF, Wood AR, Lin X, Manning A, Weedon MN. Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height. Nat Commun. 2024 Oct 03; 15(1):8549. PMID: 39362880.

Published on 9/16/2024

Chen J, Ragab AAY, Doyle MF, Alosco ML, Fang Y, Mez J, Satizabal CL, Qiu WQ, Murabito JM, Lunetta KL. Inflammatory protein associations with brain MRI measures: Framingham Offspring Cohort. Alzheimers Dement. 2024 Nov; 20(11):7465-7478. PMID: 39282876.

Published on 9/11/2024

Spartano NL, Sultana N, Lin H, Cheng H, Lu S, Fei D, Murabito JM, Walker ME, Wolpert HA, Steenkamp DW. Defining continuous glucose monitor time in range in a large community-based cohort without diabetes. J Clin Endocrinol Metab. 2024 Sep 11. PMID: 39257191.

View full list of 299 publications.