Jie Zhang PhD
Assistant Professor, Nephrology
650 Albany St | (617) 638-7338Jie.Zhang@bmc.org
jzhang7@bu.edu
Sections
Nephrology
Biography
Jie Zhang, PhD, is an Assistant Professor of Medicine at Boston University Chobanian & Avedisian School of Medicine and a Principal Investigator of Nephrology at Boston Medical Center. Dr. Zhang received her BS degree from Jilin University in China and her PhD degree from the University of South Florida. She joined the faculty of BU/BMC and established her independent research laboratory in 2023. Dr. Zhang’s laboratory employs a combination of classical renal physiology techniques such as micropuncture and microperfusion, as well as cutting-edge molecular biology technologies such as single-cell RNA sequencing and genetically engineered animal models to explore fundamental questions within the field of nephrology. Her research endeavors have been supported by prestigious fellowships and grants, including the American Heart Association Pre-Doctoral Fellowship, the American Society of Nephrology Ben J. Lipps Post-Doctoral Fellowship, the American Society of Nephrology Carl W. Gottschalk Research Scholar Grant, and NIH-NIDDK R01 Grant.
Websites
Education
Physiology, PhD, University of South Florida
Physiology, PhD, University of Mississippi
Biology, BS, Jilin University
Publications
Iglesias M, Wang H, Krause-Hauch M, Ren D, Zoungrana LI, Li Z, Zhang J, Wei J, Yadav N, Patel K, Fatmi MK, Liu R, Lesnefsky EJ, Li J. Sestrin2 Mediates Metformin Rescued the Age-Related Cardiac Dysfunctions of Cardiorenal Syndrome Type 3. Cells. 2023 Mar 08; 12(6). PMID: 36980186.
Published on 1/30/2023Liu R, Juncos LA, Lu Y, Wei J, Zhang J, Wang L, Lai EY, Carlstrom M, Persson AEG. The Role of Macula Densa Nitric Oxide Synthase 1 Beta Splice Variant in Modulating Tubuloglomerular Feedback. Compr Physiol. 2023 Jan 30; 13(1):4215-4229. PMID: 36715280.
Published on 8/1/2022Zhang J, Cai J, Cui Y, Jiang S, Wei J, Kim YC, Chan J, Thalakola A, Le T, Xu L, Wang L, Jiang K, Wang X, Wang H, Cheng F, Buggs J, Koepsell H, Vallon V, Liu R. Corrigendum to Zhang J, Cai J, Cui Y, Jiang S, Wei J, Kim YC, Chan J, Thalakola A, Le T, Xu L, Wang L, Jiang K, Wang X, Wang H, Cheng F, Buggs J, Koepsell H, Vallon V, Liu R. "Role of the macula densa sodium glucose cotransporter type 1-neuronal nitric oxide synthase-tubuloglomerular feedback pathway in diabetic hyperfiltration." Kidney Int. 2022;101:541-550. Kidney Int. 2022 Aug; 102(2):448. PMID: 35870819.
Published on 3/9/2022Chen W, Wang L, Liang P, Mast J, Mathis C, Liu CY, Wei J, Zhang J, Fu L, Juncos LA, Buggs J, Liu R. Reducing ischemic kidney injury through application of a synchronization modulation electric field to maintain Na+/K+-ATPase functions. Sci Transl Med. 2022 Mar 09; 14(635):eabj4906. PMID: 35263146.
Published on 11/26/2021Zhang J, Cai J, Cui Y, Jiang S, Wei J, Kim YC, Chan J, Thalakola A, Le T, Xu L, Wang L, Jiang K, Wang X, Wang H, Cheng F, Buggs J, Koepsell H, Vallon V, Liu R. Role of the macula densa sodium glucose cotransporter type 1-neuronal nitric oxide synthase-tubuloglomerular feedback pathway in diabetic hyperfiltration. Kidney Int. 2022 Mar; 101(3):541-550. PMID: 34843754.
Published on 10/18/2021Zhang J, Wang X, Cui Y, Jiang S, Wei J, Chan J, Thalakola A, Le T, Xu L, Zhao L, Wang L, Jiang K, Cheng F, Patel T, Buggs J, Vallon V, Liu R. Knockout of Macula Densa Neuronal Nitric Oxide Synthase Increases Blood Pressure in db/db Mice. Hypertension. 2021 Dec; 78(6):1760-1770. PMID: 34657443.
Published on 6/14/2021Wei J, Zhang J, Jiang S, Xu L, Qu L, Pang B, Jiang K, Wang L, Intapad S, Buggs J, Cheng F, Mohapatra S, Juncos LA, Osborn JL, Granger JP, Liu R. Macula Densa NOS1ß Modulates Renal Hemodynamics and Blood Pressure during Pregnancy: Role in Gestational Hypertension. J Am Soc Nephrol. 2021 Oct; 32(10):2485-2500. PMID: 34127535.
Published on 10/12/2020Zhang J, Qu L, Wei J, Jiang S, Xu L, Wang L, Cheng F, Jiang K, Buggs J, Liu R. A new mechanism for the sex differences in angiotensin II-induced hypertension: the role of macula densa NOS1ß-mediated tubuloglomerular feedback. Am J Physiol Renal Physiol. 2020 Nov 01; 319(5):F908-F919. PMID: 33044868.
Published on 12/23/2019Zhang J, Zhu J, Wei J, Jiang S, Xu L, Qu L, Yang K, Wang L, Buggs J, Cheng F, Tan X, Liu R. New Mechanism for the Sex Differences in Salt-Sensitive Hypertension: The Role of Macula Densa NOS1ß-Mediated Tubuloglomerular Feedback. Hypertension. 2020 Feb; 75(2):449-457. PMID: 31865794.
Published on 12/16/2019Wei J, Zhu J, Zhang J, Jiang S, Qu L, Wang L, Buggs J, Tan X, Cheng F, Liu R. Aging Impairs Renal Autoregulation in Mice. Hypertension. 2020 Feb; 75(2):405-412. PMID: 31838907.