Jeffrey H. Samet MD, MA, MPH

Professor, General Internal Medicine

Professor, Community Health Sciences

801 Massachusetts Ave | (617) 414-7444
Jeffrey Samet
Sections

General Internal Medicine

Centers

Clinical Addiction Research and Education Unit

Evans Center for Interdisciplinary Biomedical Research

Biography

My research has focused on alcohol and drug use, HIV infection and primary medical care with the following specific projects: linkage of alcohol and drug use treatment and primary medical care; addressing alcohol and drug use issues in the primary care setting; the impact of alcohol and drug use in HIV-infected persons; HIV prevention and treatment in Russian substance users; and establishing medical care for HIV-infected persons.

Education

Medicine, MD, Baylor College of Medicine

Epidemiology, MPH, Boston University

Chemistry, MA, Brandeis University

BA, Brandeis University

Publications

Published on 6/3/2026

Truong V, Kekibiina A, Muyindike WR, Gnatienko N, Tsui JI, Emenyonu NI, Cheng DM, Hahn JA, Allison O, Bullard MJ, Lunze K, Samet JH. Gabapentin to achieve HIV viral load suppression in people with risky drinking in Mbarara, Uganda: study protocol for a randomized, double-blinded, placebo-controlled trial (GRAIL). Trials. 2026 Jun 03. PMID: 42237416.

Published on 5/28/2026

Rossi SL, Cheng DM, Sereda Y, Truong V, Carroll JJ, Kiriazova T, Lodi S, Michals A, Raj A, Krupitsky E, Lioznov D, Samet JH, Lunze K. COVID-19 pandemic-related stress and substance use behaviors among people with HIV - a mixed method analysis. PLoS One. 2026; 21(5):e0349567. PMID: 42207818.

Published on 4/30/2026

Chhatwal J, Sahinkoc M, Chen Q, Dowd W, Xiao J, Zarkin GA, Aldridge A, Barocas JA, Cerdá M, Fareed N, Frazier LA, Hyder A, Keyes KM, Knott CE, LaRochelle M, Linas BP, Oga E, Roberts SM, Samet JH, Schackman BR, Seiber EE, Starbird LE, Villani J, Knudsen AB, Barbosa C. Cost-effectiveness of community-based interventions for reducing opioid overdose and non-overdose deaths: simulation modeling of HEALing Communities Study. Lancet Reg Health Am. 2026 Jul; 59:101480. PMID: 42099551.

Published on 4/18/2026

Weinstein ZM, Jadovich E, Drainoni ML, LaRochelle M, Yan S, Lee J, Bettano A, Beers D, Walley AY, Samet JH. Implementation of addiction consult services and bridge clinics in the HEALing communities study in Massachusetts. Drug Alcohol Depend. 2026 Jul 01; 284:113165. PMID: 42033894.

Published on 1/18/2026

Rich ZC, Tindle HA, Cheng DM, Stein MD, Gnatienko N, Bendiks S, Forman L, Patts GJ, Krupitsky E, Freiberg MS, Samet JH. Assessing the impact of nicotinic partial agonists compared to NRT on opioid and cigarette use: A secondary analysis investigating treatment outcomes for co-occurring nicotine and opioid use. J Subst Use Addict Treat. 2026 May; 184:209904. PMID: 41558587.

Published on 11/24/2025

Bradley KA, Hyun N, Idu A, Yu O, Bobb JF, Wartko PD, Weinstein Z, Matthews AG, McCormack J, Lee AK, Samet JH. Differences in benefits of office based opioid treatment: Secondary analyses across sub-groups in the PROUD randomized controlled implementation trial. Addiction. 2026 Mar; 121(3):629-642. PMID: 41287180.

Published on 11/21/2025

Rao AV, Ghare SS, Gautam V, Hoffman KL, Petrosino J, So-Armah K, Samet JH, Patts GJ, Cheng DM, Blokhina E, Krupitsky EM, Lioznov D, Zvartau E, McClain CJ, Tindle H, Freiberg MS, Barve SS. Sex differences in beneficial and pathogenic bacteria in People With HIV (PWH) with a history of heavy alcohol drinking. Front Microbiol. 2025; 16:1632949. PMID: 41356481.

Published on 10/15/2025

Truong V, Kekibiina A, Muyindike W, Gnatienko N, Tsui JI, Emenyonu NI, Cheng DM, Hahn J, Allison O, Bullard MJ, Lunze K, Samet JH. Gabapentin to achieve HIV viral load suppression in people with risky drinking in Mbarara, Uganda: study protocol for a randomized, double-blinded, placebo-controlled trial (GRAIL). Res Sq. 2025 Oct 15. PMID: 41282191.

Published on 10/11/2025

El-Bassel N, Samet JH, Cheng DM, Freisthler B, John Winhusen T, Walsh SL. Response to the Editor: Re: registration and multiple outcome testing in the HEALing Communities Study by Dennis M. Gorman and Ben G. Fitzpatrick. Int J Drug Policy. 2025 Nov; 145:105029. PMID: 41077014.

Published on 9/26/2025

Katz R, Fisher T, Singer-Clark T, Soares Iii W, Carpenter J, Schuessler N, Stadler H, Sahovey A, McAlearney AS, Samet JH, Chatterjee A. Creation of a telehealth addiction consultation service at a rural hospital: a case study. Addict Sci Clin Pract. 2025 Sep 26; 20(1):76. PMID: 41013782.

View full list of 503 publications.