Jacob Joseph MD
Adjunct Associate Professor, Cardiovascular Medicine
72 E. Concord Street | (617) 638-5300jacob.joseph@va.gov
jajoseph@bu.edu
Sections
Cardiovascular Medicine
Centers
Evans Center for Interdisciplinary Biomedical Research
Biography
Dr. Jacob Joseph is a cardiologist in West Roxbury, Massachusetts and is affiliated with multiple hospitals in the area, including Boston Medical Center and Brigham and Women's Hospital. He received his medical degree from University of Kerala Medical College and has been in practice for more than 20 years.
Education
MD, University of Kerala (UoK)
MBBS, University of Kerala (UoK)
Publications
Rasooly D, Giambartolomei C, Peloso GM, Dashti H, Ferolito BR, Golden D, Horimoto ARVR, Pietzner M, Farber-Eger EH, Wells QS, Bini G, Proietti G, Tartaglia GG, Kosik NM, Wilson PWF, Phillips LS, Munroe PB, Petersen SE, Cho K, Gaziano JM, Leach AR, Whittaker J, Langenberg C, Aung N, Sun YV, Pereira AC, Casas JP, Joseph J. Large-scale multi-omics identifies drug targets for heart failure with reduced and preserved ejection fraction. Nat Cardiovasc Res. 2025 Feb 06. PMID: 39915329.
Published on 2/5/2025Li Y, Nguyen XT, Treu T, Wang DD, Ho YL, Houghton SC, Charest B, Li R, Posner D, Pyatt M, Rahafrooz M, Raghavan S, Gagnon DR, Whitbourne SB, Gaziano JM, Djousse L, Joseph J, Wilson PWF, Cho K. Association of Life's Essential 8 With Incident Heart Failure and Its Prognosis. J Card Fail. 2025 Mar; 31(3):598-602. PMID: 39920917.
Published on 7/9/2024Kurgansky KE, Parker R, Djousse L, Gagnon DR, Joseph J. Spironolactone Reduces the Risk of Death in Veterans With Heart Failure With Preserved Ejection Fraction. J Am Heart Assoc. 2024 Jul 16; 13(14):e032231. PMID: 38979805.
Published on 10/19/2023Yuyun MF, Joseph J, Erqou SA, Kinlay S, Echouffo-Tcheugui JB, Peralta AO, Hoffmeister PS, Boden WE, Yarmohammadi H, Martin DT, Singh JP. Persistence of significant secondary mitral regurgitation post-cardiac resynchronization therapy and survival: a systematic review and meta-analysis : Mitral regurgitation and mortality post-CRT. Heart Fail Rev. 2024 Jan; 29(1):165-178. PMID: 37855988.
Published on 12/14/2022Joseph J, Liu C, Hui Q, Aragam K, Wang Z, Charest B, Huffman JE, Keaton JM, Edwards TL, Demissie S, Djousse L, Casas JP, Gaziano JM, Cho K, Wilson PWF, Phillips LS, O'Donnell CJ, Sun YV. Genetic architecture of heart failure with preserved versus reduced ejection fraction. Nat Commun. 2022 Dec 14; 13(1):7753. PMID: 36517512.
Published on 12/12/2022Huang S, Cai T, Weber BN, He Z, Dahal KP, Hong C, Hou J, Seyok T, Cagan A, DiCarli MF, Joseph J, Kim SC, Solomon DH, Cai T, Liao KP. Association Between Inflammation, Incident Heart Failure, and Heart Failure Subtypes in Patients With Rheumatoid Arthritis. Arthritis Care Res (Hoboken). 2023 May; 75(5):1036-1045. PMID: 34623035.
Published on 11/5/2022Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM. Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk. N Engl J Med. 2022 Nov 24; 387(21):1923-1934. PMID: 36342113.
Published on 10/31/2022Gaziano L, Sun L, Arnold M, Bell S, Cho K, Kaptoge SK, Song RJ, Burgess S, Posner DC, Mosconi K, Robinson-Cohen C, Mason AM, Bolton TR, Tao R, Allara E, Schubert P, Chen L, Staley JR, Staplin N, Altay S, Amiano P, Arndt V, Ärnlöv J, Barr ELM, Björkelund C, Boer JMA, Brenner H, Casiglia E, Chiodini P, Cooper JA, Coresh J, Cushman M, Dankner R, Davidson KW, de Jongh RT, Donfrancesco C, Engström G, Freisling H, de la Cámara AG, Gudnason V, Hankey GJ, Hansson PO, Heath AK, Hoorn EJ, Imano H, Jassal SK, Kaaks R, Katzke V, Kauhanen J, Kiechl S, Koenig W, Kronmal RA, Kyrø C, Lawlor DA, Ljungberg B, MacDonald C, Masala G, Meisinger C, Melander O, Moreno Iribas C, Ninomiya T, Nitsch D, Nordestgaard BG, Onland-Moret C, Palmieri L, Petrova D, Garcia JRQ, Rosengren A, Sacerdote C, Sakurai M, Santiuste C, Schulze MB, Sieri S, Sundström J, Tikhonoff V, Tjønneland A, Tong T, Tumino R, Tzoulaki I, van der Schouw YT, Monique Verschuren WM, Völzke H, Wallace RB, Wannamethee SG, Weiderpass E, Willeit P, Woodward M, Yamagishi K, Zamora-Ros R, Akwo EA, Pyarajan S, Gagnon DR, Tsao PS, Muralidhar S, Edwards TL, Damrauer SM, Joseph J, Pennells L, Wilson PWF, Harrison S, Gaziano TA, Inouye M, Baigent C, Casas JP, Langenberg C, Wareham N, Riboli E, Gaziano JM, Danesh J, Hung AM, Butterworth AS, Wood AM, Di Angelantonio E. Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses. Circulation. 2022 Nov 15; 146(20):1507-1517. PMID: 36314129.
Published on 9/30/2022Rucker D, Joseph J. Defining the Phenotypes for Heart Failure With Preserved Ejection Fraction. Curr Heart Fail Rep. 2022 Dec; 19(6):445-457. PMID: 36178663.
Published on 2/3/2022Peloso GM, Tcheandjieu C, McGeary JE, Posner DC, Ho YL, Zhou JJ, Hilliard AT, Joseph J, O'Donnell CJ, Efird JT, Crawford DC, Wu WC, Arjomandi M, Sun YV, Assimes TL, Huffman JE. Genetic Loci Associated With COVID-19 Positivity and Hospitalization in White, Black, and Hispanic Veterans of the VA Million Veteran Program. Front Genet. 2021; 12:777076. PMID: 35222515.