Gustavo Mostoslavsky MD, PhD
Professor, Gastroenterology
Professor, Virology, Immunology & Microbiology
670 Albany St | (617) 358-1018gmostosl@bu.edu

Sections
Gastroenterology
Centers
Center for Regenerative Medicine
Pulmonary Center
Evans Center for Interdisciplinary Biomedical Research
Biography
Expertise includes: Stem cells; Induced Pluripotent Stem cells (iPSC); Gene transfer and Gene editing; Lentiviruses; Disease modeling; Intestinal organoids; Neural differentiation; Immune relevant cell differentiation.
Other Positions
Websites
Department of Medicine Faculty
Center for Regenerative Medicine
Education
MD, Universidad Nacional de Tucumán
Cell & Molecular Biology, PhD, The Hebrew University of Jerusalem
Publications
Gojanovich AD, Le NTT, Mercer RCC, Park S, Wu B, Anane A, Vultaggio JS, Mostoslavsky G, Harris DA. Abnormal synaptic architecture in iPSC-derived neurons from a multi-generational family with genetic Creutzfeldt-Jakob disease. Stem Cell Reports. 2024 Oct 08; 19(10):1474-1488. PMID: 39332406.
Published on 11/28/2023Yeung AK, Villacorta-Martin C, Lindstrom-Vautrin J, Belkina AC, Vanuytsel K, Dowrey TW, Ysasi AB, Bawa P, Wang F, Vrbanac V, Mostoslavsky G, Balazs AB, Murphy GJ. De novo hematopoiesis from the fetal lung. Blood Adv. 2023 Nov 28; 7(22):6898-6912. PMID: 37729429.
Published on 11/3/2022Heinze D, Park S, McCracken A, Haratianfar M, Lindstrom J, Villacorta-Martin C, Mithal A, Wang F, Yang MW, Murphy G, Mostoslavsky G. Notch activation during early mesoderm induction modulates emergence of the T/NK cell lineage from human iPSCs. Stem Cell Reports. 2022 Dec 13; 17(12):2610-2628. PMID: 36332629.
Published on 9/8/2022Scoon WA, Mancio-Silva L, Suder EL, Villacorta-Martin C, Lindstrom-Vautrin J, Bernbaum JG, Mazur S, Johnson RF, Olejnik J, Flores EY, Mithal A, Wang F, Hume AJ, Kaserman JE, March-Riera S, Wilson AA, Bhatia SN, Mühlberger E, Mostoslavsky G. Ebola virus infection induces a delayed type I IFN response in bystander cells and the shutdown of key liver genes in human iPSC-derived hepatocytes. Stem Cell Reports. 2022 Oct 11; 17(10):2286-2302. PMID: 36084636.
Published on 7/29/2022Berical A, Lee RE, Lu J, Beermann ML, Le Suer JA, Mithal A, Thomas D, Ranallo N, Peasley M, Stuffer A, Bukis K, Seymour R, Harrington J, Coote K, Valley H, Hurley K, McNally P, Mostoslavsky G, Mahoney J, Randell SH, Hawkins FJ. A multimodal iPSC platform for cystic fibrosis drug testing. Nat Commun. 2022 Jul 29; 13(1):4270. PMID: 35906215.
Published on 3/1/2022Vanuytsel K, Villacorta-Martin C, Lindstrom-Vautrin J, Wang Z, Garcia-Beltran WF, Vrbanac V, Parsons D, Lam EC, Matte TM, Dowrey TW, Kumar SS, Li M, Wang F, Yeung AK, Mostoslavsky G, Dries R, Campbell JD, Belkina AC, Balazs AB, Murphy GJ. Multi-modal profiling of human fetal liver hematopoietic stem cells reveals the molecular signature of engraftment. Nat Commun. 2022 03 01; 13(1):1103. PMID: 35232959.
Published on 1/15/2022Wang Q, Feng L, Zhang H, Gao J, Mao C, Landesman-Bollag E, Mostoslavsky G, Lunderberg JM, Zheng W, Hao S, Gao W. Longitudinal waning of mRNA vaccine-induced neutralizing antibodies against SARS-CoV-2 detected by an LFIA rapid test. Antib Ther. 2022 Jan; 5(1):55-62. PMID: 35146332.
Published on 11/25/2021Casalia ML, Casabona JC, García C, Cavaliere Candedo V, Quintá HR, Farías MI, Gonzalez J, Gonzalez Morón D, Córdoba M, Consalvo D, Mostoslavsky G, Urbano FJ, Pasquini J, Murer MG, Rela L, Kauffman MA, Pitossi FJ. A familiar study on self-limited childhood epilepsy patients using hIPSC-derived neurons shows a bias towards immaturity at the morphological, electrophysiological and gene expression levels. Stem Cell Res Ther. 2021 11 25; 12(1):590. PMID: 34823607.
Published on 11/20/2021Chahla RE, Tomas-Grau RH, Cazorla SI, Ploper D, Vera Pingitore E, López MA, Aznar P, Alcorta ME, Vélez EMDM, Stagnetto A, Ávila CL, Maldonado-Galdeano C, Socias SB, Heinze D, Navarro SA, Llapur CJ, Costa D, Flores I, Edelstein A, Kowdle S, Perandones C, Lee B, Apfelbaum G, Mostoslavsky R, Mostoslavsky G, Perdigón G, Chehín RN. Long-term analysis of antibodies elicited by SPUTNIK V: A prospective cohort study in Tucumán, Argentina. Lancet Reg Health Am. 2022 Feb; 6:100123. PMID: 34841388.
Published on 10/14/2021Tomas-Grau RH, Ploper D, Ávila CL, Vera Pingitore E, Maldonado Galdeano C, Chaves S, Socias SB, Stagnetto A, Navarro SA, Chahla RE, Aguilar López M, Llapur CJ, Aznar P, Alcorta ME, Costas D, Flores I, Heinze D, Apfelbaum G, Mostoslavsky R, Mostoslavsky G, Cazorla SI, Perdigón GDV, Chehín R. Elevated Humoral Immune Response to SARS-CoV-2 at High Altitudes Revealed by an Anti-RBD "In-House" ELISA. Front Med (Lausanne). 2021; 8:720988. PMID: 34722566.
Media Mentions
Published on 9/27/2024
Published on 2/17/2023
BU Researchers Join $100 Million Effort to Fight Future Deadly Pathogens
Published on 2/6/2023
Published on 11/4/2022
Researchers develop novel platform to improve immunotherapy
Published on 9/9/2022
Stem Cell Research Gives New Clues on Ebola Virus Damage to Organs
Published on 9/8/2022
Researchers use stem cells to investigate liver damage from the Ebola virus
Published on 9/8/2022
Researchers harness stem cells to study how Ebola virus infects and damages the liver
Published on 4/14/2021
Stem cell-derived organoids developed to test SARS-CoV-2 drugs on gut
Published on 4/14/2021
Intestinal Organoids Developed to Test New Drugs for COVID-19
Published on 8/20/2018
After a decade of squabbles, BU’s biolab is in business
View full list of 10 media mentions.