Gustavo Mostoslavsky MD, PhD

Published on 3/23/2026

Hayes KM, Boldt K, Schnorr PJ, Bawa P, Abyazi ML, Ware MS, Gyimesi G, James M, Ko HM, Cunningham-Rundles C, Mizgerd JP, Mostoslavsky G, Kotton DN, Maglione PJ. Heterozygous NFKB1 variant causes inflammatory dysregulation shaped by broader genetic context in common variable immunodeficiency. JCI Insight. 2026 Mar 23; 11(6). PMID: 41869721.

Published on 11/24/2025

Flores EY, Hume AJ, Olejnik J, Mithal A, D'Amico A, Yang M, Bawa P, Wang F, O'Connell AK, Tseng A, Crossland NA, Mostoslavsky G, Mühlberger E. Filovirus infection disrupts epithelial barrier function and ion transport in human iPSC-derived gut organoids. PLoS Pathog. 2025 Nov; 21(11):e1013698. PMID: 41284734.

Published on 10/6/2025

Skeete C, Sgambettera G, Gojanovich AD, He X, Bryant D, Yang M, Banerjee S, Quiñones-Molina AA, Akiyama H, Mostoslavsky G, Henderson AJ, Gummuluru S. Mu opioid receptor activation in microglia enhances HIV-1 infection and HIV-infection-induced inflammatory responses. Front Immunol. 2025; 16:1628872. PMID: 41122167.

Published on 9/8/2025

Jalloh S, Hughes IK, Akiyama H, Gojanovich AD, Quiñones-Molina AA, Yang M, Henderson AJ, Mostoslavsky G, Gummuluru S. Expression of intron-containing HIV-1 RNA induces NLRP1 inflammasome activation in myeloid cells. PLoS Biol. 2025 Sep; 23(9):e3003320. PMID: 40920844.

Published on 5/15/2025

Flores EY, Mithal A, Bawa P, Wang F, D'Amico A, O'Connell AK, Gertje HP, Tseng AE, Crossland NA, Alekseyev Y, Mostoslavsky G. Human-induced Pluripotent Stem Cell-derived Gut Organoids Recapitulate Regional Specific Genetic Programs and a Role for cAMP in Lineage Specification. Cell Mol Gastroenterol Hepatol. 2025; 19(9):101534. PMID: 40381917.

Published on 9/26/2024

Gojanovich AD, Le NTT, Mercer RCC, Park S, Wu B, Anane A, Vultaggio JS, Mostoslavsky G, Harris DA. Abnormal synaptic architecture in iPSC-derived neurons from a multi-generational family with genetic Creutzfeldt-Jakob disease. Stem Cell Reports. 2024 Oct 08; 19(10):1474-1488. PMID: 39332406.

Published on 11/28/2023

Yeung AK, Villacorta-Martin C, Lindstrom-Vautrin J, Belkina AC, Vanuytsel K, Dowrey TW, Ysasi AB, Bawa P, Wang F, Vrbanac V, Mostoslavsky G, Balazs AB, Murphy GJ. De novo hematopoiesis from the fetal lung. Blood Adv. 2023 Nov 28; 7(22):6898-6912. PMID: 37729429.

Published on 11/3/2022

Heinze D, Park S, McCracken A, Haratianfar M, Lindstrom J, Villacorta-Martin C, Mithal A, Wang F, Yang MW, Murphy G, Mostoslavsky G. Notch activation during early mesoderm induction modulates emergence of the T/NK cell lineage from human iPSCs. Stem Cell Reports. 2022 Dec 13; 17(12):2610-2628. PMID: 36332629.

Published on 9/8/2022

Scoon WA, Mancio-Silva L, Suder EL, Villacorta-Martin C, Lindstrom-Vautrin J, Bernbaum JG, Mazur S, Johnson RF, Olejnik J, Flores EY, Mithal A, Wang F, Hume AJ, Kaserman JE, March-Riera S, Wilson AA, Bhatia SN, Mühlberger E, Mostoslavsky G. Ebola virus infection induces a delayed type I IFN response in bystander cells and the shutdown of key liver genes in human iPSC-derived hepatocytes. Stem Cell Reports. 2022 Oct 11; 17(10):2286-2302. PMID: 36084636.

Published on 7/29/2022

Berical A, Lee RE, Lu J, Beermann ML, Le Suer JA, Mithal A, Thomas D, Ranallo N, Peasley M, Stuffer A, Bukis K, Seymour R, Harrington J, Coote K, Valley H, Hurley K, McNally P, Mostoslavsky G, Mahoney J, Randell SH, Hawkins FJ. A multimodal iPSC platform for cystic fibrosis drug testing. Nat Commun. 2022 Jul 29; 13(1):4270. PMID: 35906215.