Gareth J Morgan PhD

Research Assistant Professor, Hematology & Medical Oncology

Member, Genome Science Institute

72 E. Concord Street | (617) 358-4750
Gareth Morgan
Sections

Hematology & Medical Oncology

Centers

BU-BMC Cancer Center

Amyloidosis Center

Biography

Gareth Morgan, PhD is a Research Assistant Professor at the Chobanian and Avedisian School of Medicine. His research focuses on the molecular mechanisms of AL amyloidosis with the aim of developing new treatments for this disease.

Other Positions

Education

Biochemistry, PhD, University of Sheffield

Biochemistry, BS, Imperial College London

Publications

Published on 3/1/2024

Wong S, West ME, Morgan GJ. Kinetic evidence for multiple aggregation pathways in antibody light chain variable domains. Protein Sci. 2024 Mar; 33(3):e4871. PMID: 38100259.

Published on 1/8/2024

Chen X, Varma G, Davies F, Morgan G. Approach to High-Risk Multiple Myeloma. Hematol Oncol Clin North Am. 2024 Apr; 38(2):497-510. PMID: 38195306.

Published on 8/28/2023

Wong S, West ME, Morgan GJ. Kinetic evidence for multiple aggregation pathways in antibody light chain variable domains. bioRxiv. 2023 Aug 28. PMID: 37693524.

Published on 6/6/2023

Yan NL, Morgan GJ, Petrassi HM, Wilson IA, Kelly JW. Pharmacological stabilization of the native state of full-length immunoglobulin light chains to treat light chain amyloidosis. Curr Opin Chem Biol. 2023 Aug; 75:102319. PMID: 37279624.

Published on 4/18/2023

Nau A, Shen Y, Sanchorawala V, Prokaeva T, Morgan GJ. Complete variable domain sequences of monoclonal antibody light chains identified from untargeted RNA sequencing data. Front Immunol. 2023; 14:1167235. PMID: 37143670.

Published on 1/19/2022

Yan NL, Nair R, Chu A, Wilson IA, Johnson KA, Morgan GJ, Kelly JW. Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site. Bioorg Med Chem Lett. 2022 03 15; 60:128571. PMID: 35065233.

Published on 10/30/2021

Morgan GJ. Transient disorder along pathways to amyloid. Biophys Chem. 2022 02; 281:106711. PMID: 34839162.

Published on 10/5/2021

Morgan GJ, Buxbaum JN, Kelly JW. Light Chain Stabilization: A Therapeutic Approach to Ameliorate AL Amyloidosis. Hemato. 2021 Dec; 2(4):645-659. PMID: 35757512.

Published on 6/11/2021

Morgan GJ. Barriers to Small Molecule Drug Discovery for Systemic Amyloidosis. Molecules. 2021 Jun 11; 26(12). PMID: 34208058.

Published on 5/3/2021

Yan NL, Santos-Martins D, Nair R, Chu A, Wilson IA, Johnson KA, Forli S, Morgan GJ, Petrassi HM, Kelly JW. Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design. J Med Chem. 2021 05 13; 64(9):6273-6299. PMID: 33939422.

View full list of 29 publications.