Gareth J. Morgan PhD
Research Assistant Professor, Hematology & Medical Oncology
Member, Genome Science Institute
72 E. Concord Street | (617) 358-4750gjmorgan@bu.edu
Sections
Hematology & Medical Oncology
Centers
BU-BMC Cancer Center
Amyloidosis Center
Biography
Gareth Morgan, PhD is a Research Assistant Professor at the Chobanian and Avedisian School of Medicine. His research focuses on the molecular mechanisms of AL amyloidosis with the aim of developing new treatments for this disease.
Other Positions
Education
Biochemistry, PhD, University of Sheffield
Biochemistry, BS, Imperial College London
Publications
Morgan GJ. How a stabilizing modification leads to misfolding disease. Structure. 2026 Aug 06; 34(8):1105-1107. PMID: 42561920.
Published on 8/5/2026Salazar Adum JP, Morgan GJ, Stefanescu Schmidt AC. A Paradox of Choice: Personalizing Transcatheter Pulmonary Valve Replacement. JACC Case Rep. 2026 Aug 05; 31(31):109317. PMID: 42559994.
Published on 6/29/2026Peterle D, Yan NL, Klimtchuk ES, Srinivasu BY, Brusic V, Rhoades D, Wales TE, Gursky O, Kelly JW, Engen JR, Morgan GJ. Small Molecule Stabilization of Diverse Amyloidogenic Immunoglobulin Light Chains Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry. J Mol Biol. 2026 Oct 01; 438(19):169917. PMID: 42372939.
Published on 1/8/2026Peterle D, Yan NL, Klimtchuk ES, Wales TE, Gursky O, Kelly JW, Engen JR, Morgan GJ. Small molecule stabilization of diverse amyloidogenic immunoglobulin light chains revealed by hydrogen-deuterium exchange mass spectrometry. bioRxiv. 2026 Jan 08. PMID: 41542593.
Published on 11/14/2025Bassett PT, Nguyen BA, Singh V, Garrett PT, Moresco JJ, Eddy J, Afrin S, Pekala M, Lopez C, Evers BM, Ahmed Y, Grodin JL, Roth LR, Kaur G, Chung S, Morgan GJ, Yates JR, Saelices L. Polymorphic IGLV6-57 AL amyloid fibrils and features of a shared folding pathway. bioRxiv. 2025 Nov 14. PMID: 41292724.
Published on 8/1/2025Morgan GJ, Prokaeva T. Clone-specific residue changes at multiple positions are associated with amyloid formation by antibody light chains. Front Immunol. 2025; 16:1622207. PMID: 40861476.
Published on 3/25/2025Edwards CV, Ferri GM, Villegas-Galaviz J, Ghosh S, Singh Bawa P, Wang F, Klimtchuk E, Ajayi TB, Morgan GJ, Prokaeva T, Staron A, Ruberg FL, Sanchorawala V, Giadone RM, Murphy GJ. Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition. Amyloid. 2025 Jun; 32(2):179-192. PMID: 40134188.
Published on 12/6/2024Morgan GJ, Nau AN, Wong S, Spencer BH, Shen Y, Hua A, Bullard MJ, Sanchorawala V, Prokaeva T. An updated AL-base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis. Amyloid. 2025 Jun; 32(2):129-138. PMID: 39641756.
Published on 11/16/2024Morgan GJ, Yung Z, Spencer BH, Sanchorawala V, Prokaeva T. Predicting Structural Consequences of Antibody Light Chain N-Glycosylation in AL Amyloidosis. Pharmaceuticals (Basel). 2024 Nov 16; 17(11). PMID: 39598451.
Published on 10/28/2024Klimtchuk ES, Prokaeva T, Spencer BH, Wong S, Ghosh S, Urdaneta A, Morgan G, Wales TE, Gursky O. Conformational Differences in the Light Chain Constant Domain of Immunoglobulin G and Free Light Chain May Influence Proteolysis in AL Amyloidosis. J Mol Biol. 2024 Dec 01; 436(23):168837. PMID: 39490919.
Media Mentions
Published on 4/25/2023
Amyloidosis: Beyond Alzheimer’s and Parkinson’s
Published on 4/16/2023
Alzheimer’s-Like Diseases Can Affect the Body — Scientists Are Working to Find Out Why
Published on 4/5/2023
Amyloidosis: Beyond Alzheimer’s and Parkinson’s
View full list of 3 media mentions.