Finn Hawkins MBBCh

Assistant Professor, Pulmonary, Allergy, Sleep & Critical Care Medicine

Graduate Faculty (Primary Mentor of Grad Students)

72 E. Concord Street | (617) 638-4860
Finn Hawkins
Sections

Pulmonary, Allergy, Sleep & Critical Care Medicine

Centers

Center for Regenerative Medicine

Pulmonary Center

Evans Center for Interdisciplinary Biomedical Research

Biography

Dr. Hawkins is a Principal Investigator (P.I.) in the Center for Regenerative Medicine and The Pulmonary Center. His research focus is studying human lung development and disease using human induced pluripotent stem cells (iPSCs). Dr. Hawkins is currently using iPSC technology to study airway biology with a focus on Cystic Fibrosis.

Education

MBBCh, National University of Ireland, 1998

Publications

Published on 7/20/2021

Suzuki S, Hawkins FJ, Barillà C, Beermann ML, Kotton DN, Davis BR. Differentiation of human pluripotent stem cells into functional airway basal stem cells. STAR Protoc. 2021 Sep 17; 2(3):100683. PMID: 34355203.

Published on 6/29/2021

Smyth R, Sloan JM, Burks E, Hawkins F. Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates. Respirol Case Rep. 2021 Aug; 9(8):e00806. PMID: 34221408.

Published on 10/23/2020

Hawkins FJ, Suzuki S, Beermann ML, Barillà C, Wang R, Villacorta-Martin C, Berical A, Jean JC, Le Suer J, Matte T, Simone-Roach C, Tang Y, Schlaeger TM, Crane AM, Matthias N, Huang SXL, Randell SH, Wu J, Spence JR, Carraro G, Stripp BR, Rab A, Sorsher EJ, Horani A, Brody SL, Davis BR, Kotton DN. Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2021 01 07; 28(1):79-95.e8. PMID: 33098807.

Published on 9/18/2020

Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Lindstrom-Vautrin J, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. Cell Stem Cell. 2020 12 03; 27(6):962-973.e7. PMID: 32979316.

Published on 9/8/2020

King NE, Suzuki S, Barillà C, Hawkins FJ, Randell SH, Reynolds SD, Stripp BR, Davis BR. Correction of Airway Stem Cells: Genome Editing Approaches for the Treatment of Cystic Fibrosis. Hum Gene Ther. 2020 09; 31(17-18):956-972. PMID: 32741223.

Published on 6/30/2020

Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. bioRxiv. 2020 Jun 30. PMID: 32637964.

Published on 6/4/2020

Abo KM, Ma L, Matte T, Huang J, Alysandratos KD, Werder RB, Mithal A, Beermann ML, Lindstrom-Vautrin J, Mostoslavsky G, Ikonomou L, Kotton DN, Hawkins F, Wilson A, Villacorta-Martin C. Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors. bioRxiv. 2020 Jun 04. PMID: 32577635.

Published on 4/25/2020

Wang R, McCauley KB, Kotton DN, Hawkins F. Differentiation of human airway-organoids from induced pluripotent stem cells (iPSCs). Methods Cell Biol. 2020; 159:95-114. PMID: 32586451.

Published on 2/6/2020

De Santi C, Fernández Fernández E, Gaul R, Vencken S, Glasgow A, Oglesby IK, Hurley K, Hawkins F, Mitash N, Mu F, Raoof R, Henshall DC, Cutrona MB, Simpson JC, Harvey BJ, Linnane B, McNally P, Cryan SA, MacLoughlin R, Swiatecka-Urban A, Greene CM. Precise Targeting of miRNA Sites Restores CFTR Activity in CF Bronchial Epithelial Cells. Mol Ther. 2020 04 08; 28(4):1190-1199. PMID: 32059764.

Published on 1/10/2020

Mithal A, Capilla A, Heinze D, Berical A, Villacorta-Martin C, Vedaie M, Jacob A, Abo K, Szymaniak A, Peasley M, Stuffer A, Mahoney J, Kotton DN, Hawkins F, Mostoslavsky G. Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells. Nat Commun. 2020 01 10; 11(1):215. PMID: 31924806.

View full list of 28 publications.