Finn Hawkins MBBCh
Associate Professor, Pulmonary, Allergy, Sleep & Critical Care Medicine
Graduate Faculty (Primary Mentor of Grad Students)
72 E. Concord Street | (617) 638-4860finn.hawkins@bmc.org
hawk@bu.edu
Sections
Pulmonary, Allergy, Sleep & Critical Care Medicine
Centers
Center for Regenerative Medicine
Pulmonary Center
Evans Center for Interdisciplinary Biomedical Research
Biography
Dr. Hawkins is a Principal Investigator (P.I.) in the Center for Regenerative Medicine and The Pulmonary Center. His research focus is studying human lung development and disease using human induced pluripotent stem cells (iPSCs). Dr. Hawkins is currently using iPSC technology to study airway biology with a focus on Cystic Fibrosis.
Education
MBBCh, National University of Ireland
Publications
Kohn A, Herriges MJ, Basak P, Ma L, Thapa BR, Kotton DN, Hawkins FJ. Targeted pre-conditioning and cell transplantation in the murine lower respiratory tract. bioRxiv. 2024 Nov 13. PMID: 39605510.
Published on 11/8/2024Berical AC, Kiyokawa H, Beermann ML, Wallman D, Cherfane G, Dunphy V, Pan J, Tilston-Lunel A, Varelas X, Horani A, Brody SL, Kotton DN, Hawkins FJ. Airway Disease Modeling with Gene-edited Human Basal Cell Transplantation. Am J Respir Crit Care Med. 2024 Nov 08. PMID: 39514838.
Published on 11/5/2024Ma L, Thapa BR, Le Suer JA, Tilston-Lünel A, Herriges MJ, Wang F, Bawa PS, Varelas X, Hawkins FJ, Kotton DN. Life-long functional regeneration of in vivo airway epithelium by the engraftment of airway basal stem cells. Nat Protoc. 2024 Nov 05. PMID: 39501108.
Published on 7/23/2024Koenitzer JR, Gupta DK, Twan WK, Xu H, Hadas N, Hawkins FJ, Beermann ML, Penny GM, Wamsley NT, Berical A, Major MB, Dutcher SK, Brody SL, Horani A. Transcriptional analysis of primary ciliary dyskinesia airway cells reveals a dedicated cilia glutathione pathway. JCI Insight. 2024 Jul 23; 9(17). PMID: 39042459.
Published on 3/21/2024Brody SL, Pan J, Huang T, Xu J, Xu H, Koenitizer J, Brennan SK, Nanjundappa R, Saba TG, Berical A, Hawkins FJ, Wang X, Zhang R, Mahjoub MR, Horani A, Dutcher SK. Loss of an extensive ciliary connectome induces proteostasis and cell fate switching in a severe motile ciliopathy. bioRxiv. 2024 Mar 21. PMID: 38562900.
Published on 3/14/2024Dagher R, Moldobaeva A, Gubbins E, Clark S, Madel Alfajaro M, Wilen CB, Hawkins F, Qu X, Chien Chiang C, Li Y, Clarke L, Ikeda Y, Brown C, Kolbeck R, Ma Q, Rojas M, Koff JL, Ghaedi M. Human iPSC-Based Model of COPD to Investigate Disease Mechanisms, Predict SARS-COV-2 Outcome, and Test Preventive Immunotherapy. Stem Cells. 2024 Mar 14; 42(3):230-250. PMID: 38183264.
Published on 1/1/2024Shankar DA, Hawkins F, Alysandratos KD, Wilson KC, Walkey AJ, Bosch NA, Law AC. Uptake of Antifibrotics for Patients with Idiopathic Pulmonary Fibrosis: 2016-2022. Ann Am Thorac Soc. 2024 Jan; 21(1):170-173. PMID: 37879035.
Published on 12/27/2023Lee RE, Mascenik TM, Major SC, Galiger JR, Bulik-Sullivan E, Siesser PF, Lewis CA, Bear JE, Le Suer JA, Hawkins FJ, Pickles RJ, Randell SH. Viral airway injury promotes cell engraftment in an in vitro model of cystic fibrosis cell therapy. Am J Physiol Lung Cell Mol Physiol. 2024 Mar 01; 326(3):L226-L238. PMID: 38150545.
Published on 10/20/2023Miura A, Sarmah H, Tanaka J, Hwang Y, Sawada A, Shimamura Y, Otoshi T, Kondo Y, Fang Y, Shimizu D, Ninish Z, Suer JL, Dubois NC, Davis J, Toyooka S, Wu J, Que J, Hawkins FJ, Lin CS, Mori M. Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generation of the whole lung. Elife. 2023 Oct 20; 12. PMID: 37861292.
Published on 8/24/2023Ma L, Thapa BR, Le Suer JA, Tilston-Lünel A, Herriges MJ, Berical A, Beermann ML, Wang F, Bawa PS, Kohn A, Ysasi AB, Kiyokawa H, Matte TM, Randell SH, Varelas X, Hawkins FJ, Kotton DN. Airway stem cell reconstitution by the transplantation of primary or pluripotent stem cell-derived basal cells. Cell Stem Cell. 2023 Sep 07; 30(9):1199-1216.e7. PMID: 37625411.
Media Mentions
Published on 8/22/2024
2024 Ignition Awards Aim to Bring BU Science and Tech to Market
Published on 8/31/2023
BU Researchers See Future Where Lung Disease Is Treatable, and Damaged Lungs Are Regenerated
Published on 10/27/2020
Human Airway Basal Stem Cells Created from Patients’ Cells
Published on 10/26/2020
Patient-specific airway stem cells developed to model lung diseases
Published on 9/8/2020
What Sets Off Deadly Levels of Lung Inflammation in Some COVID-19 Patients?
Published on 7/2/2019
Chasing a Cure for Lung Disease With Stem Cells: A Conversation With Finn Hawkins
View full list of 6 media mentions.