Elaine M. Hylek MD

Professor, General Internal Medicine

801 Massachusetts Ave | (617) 414-3743
Elaine Hylek

General Internal Medicine


Evans Center for Interdisciplinary Biomedical Research


Expertise includes: Arterial Thrombosis; Venous Thrombosis; Atrial Fibrillation; Safety and Effectiveness of Antithrombotic Therapy.


MD, University of Pittsburgh School of Medicine, 1988

MPH, Harvard School of Public Health, 1993

Health Administration/Education, MS, University of Pittsburgh, 1984

Medical Technologist, BS, Pennsylvania State University, 1978


Published on 2/27/2023

Go AS, Al-Khatib SM, Desvigne-Nickens P, Bansal N, Bushnell CD, Fang MC, Freeman JV, Gage BF, Hanke T, Hylek EM, Lopes RD, Noseworthy PA, Reddy VY, Singer DE, Thomas KL, True Hills M, Turakhia MP, Zieman SJ, Cooper LS, Benjamin EJ. Research Opportunities in Stroke Prevention for Atrial Fibrillation: A Report From a National Heart, Lung, and Blood Institute Virtual Workshop. Stroke. 2023 Mar; 54(3):e75-e85. PMID: 36848427.

Published on 12/1/2022

Hylek EM. Catheter-Directed Treatment of Submassive Pulmonary Embolism-A Cautious Step Closer? JAMA Cardiol. 2022 Dec 01; 7(12):1197-1198. PMID: 36260318.

Published on 9/19/2022

Al-Khatib SM, Wojdyla DM, Granger CB, Wallentin L, Garcia DA, Hijazi Z, Held C, Alexander JH, Vinereanu D, Flaker GC, Hylek EM, Lopes RD. Duration of Anticoagulation Interruption Before Invasive Procedures and Outcomes in Patients With Atrial Fibrillation: Insights From the ARISTOTLE Trial. Circulation. 2022 Sep 20; 146(12):958-960. PMID: 36121911.

Published on 1/5/2022

Carnicelli AP, Hong H, Connolly SJ, Eikelboom J, Giugliano RP, Morrow DA, Patel MR, Wallentin L, Alexander JH, Cecilia Bahit M, Benz AP, Bohula EA, Chao TF, Dyal L, Ezekowitz M, A A Fox K, Gencer B, Halperin JL, Hijazi Z, Hohnloser SH, Hua K, Hylek E, Toda Kato E, Kuder J, Lopes RD, Mahaffey KW, Oldgren J, Piccini JP, Ruff CT, Steffel J, Wojdyla D, Granger CB. Direct Oral Anticoagulants Versus Warfarin in Patients With Atrial Fibrillation: Patient-Level Network Meta-Analyses of Randomized Clinical Trials With Interaction Testing by Age and Sex. Circulation. 2022 01 25; 145(4):242-255. PMID: 34985309.

Published on 11/15/2021

Weitz JI, Strony J, Ageno W, Gailani D, Hylek EM, Lassen MR, Mahaffey KW, Notani RS, Roberts R, Segers A, Raskob GE. Milvexian for the Prevention of Venous Thromboembolism. N Engl J Med. 2021 12 02; 385(23):2161-2172. PMID: 34780683.

Published on 10/21/2021

Rasmussen PV, Hylek E. Persistence with treatment in atrial fibrillation: still a pressing issue in the era of direct oral anticoagulants. Eur Heart J. 2021 10 21; 42(40):4138-4140. PMID: 34347053.

Published on 7/1/2021

Albers GW, Bernstein R, Brachmann J, Camm AJ, Fromm P, Goto S, Granger CB, Hohnloser SH, Hylek E, Krieger D, Passman R, Pines JM, Kowey P. Reexamination of the Embolic Stroke of Undetermined Source Concept. Stroke. 2021 08; 52(8):2715-2722. PMID: 34192898.

Published on 3/1/2021

Pol T, Hijazi Z, Lindbäck J, Alexander JH, Bahit MC, De Caterina R, Eikelboom JW, Ezekowitz MD, Gersh BJ, Granger CB, Hylek EM, Lopes R, Siegbahn A, Wallentin L. Evaluation of the prognostic value of GDF-15, ABC-AF-bleeding score and ABC-AF-death score in patients with atrial fibrillation across different geographical areas. Open Heart. 2021 03; 8(1). PMID: 33741689.

Published on 9/15/2020

Hylek EM. The importance of adherence and persistence in the elderly atrial fibrillation patient. Eur Heart J Suppl. 2020 Sep; 22(Suppl I):I38-I42. PMID: 33088233.

Published on 9/1/2020

Hijazi Z, Oldgren J, Lindbäck J, Alexander JH, Alings M, De Caterina R, Eikelboom JW, Ezekowitz MD, Held C, Huber K, Hylek EM, Granger CB, Lopes RD, Vinereanu D, Siegbahn A, Wallentin L. Evaluation of the Age, Biomarkers, and Clinical History-Bleeding Risk Score in Patients With Atrial Fibrillation With Combined Aspirin and Anticoagulation Therapy Enrolled in the ARISTOTLE and RE-LY Trials. JAMA Netw Open. 2020 09 01; 3(9):e2015943. PMID: 32936298.

View full list of 275 publications.