Elaine M. Hylek MD

Published on 4/22/2026

Parker WAE, Nelson TA, Lee J, Judge HM, Ajjan RA, Westerbergh J, Siegbahn A, Christersson C, Alexander JH, Lopes RD, Granger CB, Hylek EM, Wallentin L, Storey RF. Pre-treatment lysis time of plasma-derived fibrin clots and bleeding in patients on oral anticoagulants for atrial fibrillation in the ARISTOTLE trial. Eur Heart J. 2026 Apr 22; 47(16):1949-1960. PMID: 40444814.

Published on 2/25/2026

Piccini JP, Russo AM, Peacock J, Passman RS, Hills MT, Mittal S, Hylek EM, Hong MF, McCearley SS, Frankel DS, Kloosterman EM, Stanelle EJ, Lande JD, Rosen S, Kanwar R, Neisen KB, Richmond D, Crocker L, Lakkireddy DR. Impact of atrial fibrillation burden on quality of life and prediction of health care utilization: Primary results from the DEFINE AFib study. Heart Rhythm. 2026 Feb 25. PMID: 41759867.

Published on 2/2/2026

Reddy VY, Hylek E, Camm AJ, Halperin JL, Diener HC, Thaler D, Schmidt B, Hara H, Huisman MV, Price MJ, Lakkireddy D, Gage R, Zhao H, Jensen TP, Quintana M, Windecker S. Left Atrial Appendage Occlusion Versus NOACs in patients With Atrial Fibrillation: Rationale and Design of the CATALYST Trial. Am Heart J. 2026 Jun; 296:107367. PMID: 41638386.

Published on 12/19/2024

Jason MJ, Marzec LN, Piccini JP, Shrader P, Pieper KS, Blanco RG, Fonarow GC, Gersh BJ, Ho PM, Hylek E, Kowey PR, Mahaffey KW, Steinberg BA, Peterson ED, Allen LA. Stroke-bleeding risk score pairings within individuals in the outcomes registry for better informed treatment of atrial fibrillation (ORBIT-AF) registry. Int J Cardiol. 2025 Feb 15; 421:132912. PMID: 39708904.

Published on 10/24/2024

Piccini JP, Stanelle EJ, Johnson CC, Hylek EM, Kanwar R, Lakkireddy DR, Mittal S, Peacock J, Russo AM, Soderlund D, Hills MT, Passman RS. Performance of Atrial Fibrillation Burden Trends for Stroke Risk Stratification. Circ Arrhythm Electrophysiol. 2024 Nov; 17(11):e012394. PMID: 39445430.

Published on 10/24/2024

Peacock J, Stanelle EJ, Johnson LC, Hylek EM, Kanwar R, Lakkireddy DR, Mittal S, Passman RS, Russo AM, Soderlund D, Hills MT, Piccini JP. Using Atrial Fibrillation Burden Trends and Machine Learning to Predict Near-Term Risk of Cardiovascular Hospitalization. Circ Arrhythm Electrophysiol. 2024 Nov; 17(11):e012991. PMID: 39445440.

Published on 10/5/2024

Lakkireddy DR, Russo AM, Hylek EM, Mittal S, Peacock J, Hills MT, Stanelle EJ, Lande JD, Franco NC, Johnson LC, Kanwar R, Passman RS, Piccini JP. Use of continuous cardiac monitoring to assess the influence of atrial fibrillation burden and patterns on patient symptoms and healthcare utilization: The DEFINE AFib study. Heart Rhythm O2. 2024 Dec; 5(12):951-956. PMID: 39803627.

Published on 8/18/2023

Lim TW, Camm AJ, Virdone S, Singer DE, Bassand JP, Fonarow GC, Fox KAA, Ezekowitz M, Gersh BJ, Kayani G, Hylek EM, Kakkar AK, Mahaffey KW, Pieper KS, Peterson ED, Piccini JP. Predictors of intracranial hemorrhage in patients with atrial fibrillation treated with oral anticoagulants: Insights from the GARFIELD-AF and ORBIT-AF registries. Clin Cardiol. 2023 Nov; 46(11):1398-1407. PMID: 37596725.

Published on 2/27/2023

Go AS, Al-Khatib SM, Desvigne-Nickens P, Bansal N, Bushnell CD, Fang MC, Freeman JV, Gage BF, Hanke T, Hylek EM, Lopes RD, Noseworthy PA, Reddy VY, Singer DE, Thomas KL, True Hills M, Turakhia MP, Zieman SJ, Cooper LS, Benjamin EJ. Research Opportunities in Stroke Prevention for Atrial Fibrillation: A Report From a National Heart, Lung, and Blood Institute Virtual Workshop. Stroke. 2023 Mar; 54(3):e75-e85. PMID: 36848427.

Published on 12/1/2022

Hylek EM. Catheter-Directed Treatment of Submassive Pulmonary Embolism-A Cautious Step Closer? JAMA Cardiol. 2022 Dec 01; 7(12):1197-1198. PMID: 36260318.