Donald Lloyd-Jones MD

Professor, Preventive Medicine & Epidemiology

Director of Framingham Center for Population and Prevention Science, Framingham Heart Study

72 E. Concord Street | (617) 358-9783
Donald Lloyd-Jones
Sections

Preventive Medicine & Epidemiology

Biography

Dr. Lloyd-Jones’ research interests include the study of the mechanisms and life course of cardiovascular health and healthy aging, and cardiovascular disease epidemiology, risk estimation and prevention. Other areas of interest include the use of novel biomarkers and imaging of subclinical atherosclerosis to improve prevention, and the epidemiology and outcomes of hypertension and dyslipidemia. His clinical and teaching interests lie in general cardiology, with a focus on prevention.

He also has been a national leader in public health and clinical approaches to promoting cardiovascular health and preventing cardiovascular diseases across the life course. He served as co-chair of the Risk Assessment Guidelines and a member of the Cholesterol Treatment Guidelines Panel for the 2013 ACC/AHA Guidelines for Cardiovascular Disease Risk Reduction; and was the lead member for risk assessment on the 2018 Cholesterol Guidelines Panel and the 2019 Primary Prevention Guidelines Panel. He has authored over 750 peer-reviewed scientific publications and has been a PI or co-investigator on more than 120 grants (the vast majority from NIH)

Other Positions

Education

MD, Columbia University College of Physicians and Surgeons

MS, Harvard School of Public Health

BA, Swarthmore College

Publications

Published on 4/28/2026

Greenland P, Lloyd-Jones DM. Lipid Lowering in 2026: Still Asking When, in Whom, and How. JAMA. 2026 Apr 28; 335(16):1391-1392. PMID: 41903217.

Published on 4/16/2026

Xanthakis V, Prescott B, Ning H, Krishnan V, Lloyd-Jones DM. Relating Cumulative Life's Essential 8 Score With Cardiovascular Disease and Death: The Framingham Heart Study. JACC Adv. 2026 Apr 16; 5(5):102706. PMID: 41996786.

Published on 4/1/2026

Krishnan V, Huang X, McGowan C, Shah NS, Qureshi F, Minkovitz CS, Kershaw KN, Freedman AA, Miller GE, Lloyd-Jones DM, Khan SS. Neighborhood Indices, Income, and Cardiovascular-Kidney-Metabolic Syndrome at the Census Tract Level. JAMA Netw Open. 2026 Apr 01; 9(4):e266019. PMID: 41954933.

Published on 3/31/2026

Gao T, Zheng Y, Joyce BT, Liu L, Liu L, Kiefe C, Forrester S, Gordon-Larsen P, Liu C, Lloyd-Jones D, Zhang K, Hou L. Developing a novel index for neighborhood social determinants of cardiovascular diseases in the CARDIA study. Nat Commun. 2026 Mar 31. PMID: 41917033.

Published on 3/5/2026

Goldman N, Allen NB, Pratt B, Ning H, Schneper L, Lloyd-Jones D, Notterman D. Racial and ethnic variation in socioeconomic differentials in young adult cardiovascular health. Am J Epidemiol. 2026 Mar 05; 195(3):800-806. PMID: 40331753.

Published on 2/27/2026

Ahn JH, Kim H, Kim HC, Lee H, Lee YH, Lloyd-Jones DM, Jung SJ. Association between cardiovascular health measured by Life's Essential 8 and depressive symptoms. Epidemiol Health. 2026; 48:e2026013. PMID: 41856049.

Published on 2/26/2026

Claudel SE, Lloyd-Jones DM, Waikar SS, Verma A. Prevalence of Albuminuria Across Cardiovascular-Kidney-Metabolic Phenotypes in the United States. Diabetes Obes Metab. 2026 Feb 26. PMID: 41749339.

Published on 2/17/2026

Hernandez AV, Diaz-Arocutipa C, Valenzuela G, Feigin V, Banda S, Barboza JJ, Mayta-Tovalino F, Virú Loza MA, Persell S, Wafford E, Lloyd-Jones DM, Mead GE. Risk scoring for the primary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2026 Feb 17; 2(2):CD016333. PMID: 41700601.

Published on 2/12/2026

Davis DN, Gajjar P, Xanthakis V, Lloyd-Jones D, Nayor M. Refined Heart Failure Stages Incorporating Cardiorespiratory Fitness Are Differentially Associated With Heart Failure Risk in the Community. J Am Heart Assoc. 2026 Feb 17; 15(4):e045791. PMID: 41676947.

Published on 1/28/2026

Freedman AA, Colangelo LA, Ning H, Borrowman JD, Lewis CE, Schreiner PJ, Khan SS, Lloyd-Jones DM. Sex Differences in Age of Onset of Premature Cardiovascular Disease and Subtypes: The Coronary Artery Risk Development in Young Adults Study. J Am Heart Assoc. 2026 Feb 03; 15(3):e044922. PMID: 41605575.

View full list of 834 publications.