Donald Lloyd-Jones MD

Professor, Preventive Medicine & Epidemiology

Director of Framingham Center for Population and Prevention Science, Framingham Heart Study

72 E. Concord Street | (617) 358-9783
Donald Lloyd-Jones
Sections

Preventive Medicine & Epidemiology

Biography

Dr. Lloyd-Jones’ research interests include the study of the mechanisms and life course of cardiovascular health and healthy aging, and cardiovascular disease epidemiology, risk estimation and prevention. Other areas of interest include the use of novel biomarkers and imaging of subclinical atherosclerosis to improve prevention, and the epidemiology and outcomes of hypertension and dyslipidemia. His clinical and teaching interests lie in general cardiology, with a focus on prevention.

He also has been a national leader in public health and clinical approaches to promoting cardiovascular health and preventing cardiovascular diseases across the life course. He served as co-chair of the Risk Assessment Guidelines and a member of the Cholesterol Treatment Guidelines Panel for the 2013 ACC/AHA Guidelines for Cardiovascular Disease Risk Reduction; and was the lead member for risk assessment on the 2018 Cholesterol Guidelines Panel and the 2019 Primary Prevention Guidelines Panel. He has authored over 750 peer-reviewed scientific publications and has been a PI or co-investigator on more than 120 grants (the vast majority from NIH)

Other Positions

Education

MD, Columbia University College of Physicians and Surgeons

Epidemiology, SM/ScM, Harvard School of Public Health

History, BA, Swarthmore College

Publications

Published on 9/17/2026

Bakhshi B, Lin H, Sultana N, Healey E, Queen H, Gao G, Claudel SE, Minetti ET, Mitchell GF, Murabito JM, Lloyd-Jones DM, Cheney MC, Steenkamp DW, Nayor M, Xanthakis V, Walker ME, Spartano NL. Beyond Traditional Glycemic Measures: CGM Glycemic Profiles Reveal Associations With Cardiometabolic Risk in Individuals Without Diabetes. Diabetes Care. 2026 Sep 17. PMID: 42752803.

Published on 9/15/2026

Huang X, Petito LC, Guan W, Yee LM, Haas DM, Mercer BM, Parry S, Saade GR, Silver RM, Qiao Y, Huang X, Simhan HN, Reddy UM, Chung J, Greenland P, Lloyd-Jones DM, Grobman WA, Khan SS. Plasma Proteomic Mediators of the Association Between Early-Pregnancy Psychosocial Stress and Cardiovascular Health 2 to 7 Years After Delivery: The nuMoM2b-HHS Study. medRxiv. 2026 Sep 15. PMID: 42780155.

Published on 8/20/2026

Krishnan V, Ning H, Notterman DA, Goldman N, Khan SS, Shah NS, Allen NB, Lloyd-Jones DM. Association Between Cardiovascular-Kidney-Metabolic Health and Early Arterial Injury in Young Adults in the United States: The Future of Families-Cardiovascular Health Among Young Adults Study. Circ Popul Health Outcomes. 2026 Sep; 19(9):e013042. PMID: 42619589.

Published on 8/7/2026

Domanski MJ, Wu CO, Tian X, Shalhoub R, Miao R, Roney PC, Davis SN, Hasan AA, Reis JP, Bae S, Jacobs DR, Lloyd-Jones DM, Fuster V. Diabetes Mellitus, Cumulative Glucose Exposure, and Incident Cardiovascular Disease Risk. JACC Adv. 2026 Sep; 5(9):103087. PMID: 42567096.

Published on 8/5/2026

Khan SS, Sang Y, Huang X, Petito LC, Hong C, Pencina MJ, Ballew SH, Grams ME, Ndumele CE, Lloyd-Jones DM, Grobman WA, Coresh J. External Validation of the PREVENT Equations in a National Sample of US Adults. Circ Popul Health Outcomes. 2026 Sep; 19(9):e012988. PMID: 42554063.

Published on 8/5/2026

Goldman N, Allen NB, Pratt B, Ning H, Schneper L, Lloyd-Jones D, Notterman D. Authors' response to "Racial and Ethnic Variation in Socioeconomic Differentials in Young Adult Cardiovascular Health". Am J Epidemiol. 2026 Aug 05; 195(8):2323-2324. PMID: 42294593.

Published on 8/1/2026

Wang N, DiCorpo DA, Zhang Y, Kleinbrink E, Arnett DK, Barnard J, Blangero J, Bowden DW, Carson AP, Chen YI, Chung MK, Curran JE, Darbar D, Duggirala R, Ellinor PT, Fatkin D, Fornage M, Heard-Costa N, He J, Hou L, Kardia SLR, Kooperberg C, Loos RJF, McManus DD, Mitchell BD, Minster RL, North KE, Psaty BM, Raffield LM, Redline S, Rich SS, Roden D, Rotter JI, Shoemaker MB, Smith JD, Van Wagoner DR, Aguet F, Ardlie K, Bis JC, Brody JA, Cade BE, Clish CB, de Vries PS, Floyd JS, Freedman BI, Gabriel S, Gerzsten RE, Goodarzi MO, Gu C, Guo X, Gupta N, Heckbert SR, Hsu S, Hung YJ, Kalyani RR, Kelly TN, Kinney GL, Li C, Liu S, Liu Y, Lloyd-Jones DM, Manson JE, Mathias RA, Mercader JM, Morrison AC, Naseri T, Onengut S, Palmer ND, Peyser PA, Qi Q, Raghavan S, Reiner AP, Rooney MR, Sevilla-Gonzalez M, Sarnowski C, Smith JD, Smith JA, Spartano NL, Tahir U, Taylor KD, Tobias DK, Tracy RP, Viali S, Wang H, Wood AC, Yanek LR, Zhao W, Zheng Y, Dupuis J, Liu CT, Sladek R, Wessel J, Meigs JB, Manning AK. Colocalization of eQTLs With Type 2 Diabetes and Glycemic Traits Using Whole-Genome Sequences in Diverse Populations From the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program. Diabetes. 2026 Aug 01; 75(8):1477-1491. PMID: 42274313.

Published on 7/31/2026

Zhang Y, Schaefer EJ, Ikezaki H, Diffenderfer MR, Lloyd-Jones DM, Hoogeveen RC, Ballantyne CM, DeFilippis AP, Guan W, Tsai MY, Liu CT. Comprehensive Evaluation of Atherosclerotic Cardiovascular Disease Risk Predictors Across the Pooled Cohort Equations, Predicting Risk of Cardiovascular Disease Events, and an Expanded Model. J Am Heart Assoc. 2026 Aug 04; 15(15):e049726. PMID: 42535551.

Published on 7/27/2026

Lloyd-Jones DM. Cardiovascular-Kidney-Metabolic Syndrome: A Historic Perspective. Circulation. 2026 Jul 28; 154(4):416-419. PMID: 42507780.

Published on 7/25/2026

Gold ME, Chandrasekhar S, Kulshreshtha A, Britt M, Guynn N, Gold DA, Jain V, Razavi AC, Vatsa N, Yadalam AK, Bennett J, McLean P, Dodson S, Vaccarino V, Quyyumi AA, Lah J, Levey A, Benson R, Lloyd-Jones DM, Sperling LS. Life's Essential 8: Essential for Brain and Cognitive Health. J Am Heart Assoc. 2026 Aug 04; 15(15):e039048. PMID: 42500864.

View full list of 882 publications.