Donald Lloyd-Jones MD

Professor, Preventive Medicine & Epidemiology

Director of Framingham Center for Population and Prevention Science, Framingham Heart Study

72 E. Concord Street | (617) 358-9783
Donald Lloyd-Jones
Sections

Preventive Medicine & Epidemiology

Biography

Dr. Lloyd-Jones’ research interests include the study of the mechanisms and life course of cardiovascular health and healthy aging, and cardiovascular disease epidemiology, risk estimation and prevention. Other areas of interest include the use of novel biomarkers and imaging of subclinical atherosclerosis to improve prevention, and the epidemiology and outcomes of hypertension and dyslipidemia. His clinical and teaching interests lie in general cardiology, with a focus on prevention.

He also has been a national leader in public health and clinical approaches to promoting cardiovascular health and preventing cardiovascular diseases across the life course. He served as co-chair of the Risk Assessment Guidelines and a member of the Cholesterol Treatment Guidelines Panel for the 2013 ACC/AHA Guidelines for Cardiovascular Disease Risk Reduction; and was the lead member for risk assessment on the 2018 Cholesterol Guidelines Panel and the 2019 Primary Prevention Guidelines Panel. He has authored over 750 peer-reviewed scientific publications and has been a PI or co-investigator on more than 120 grants (the vast majority from NIH)

Other Positions

Education

MD, Columbia University College of Physicians and Surgeons

MS, Harvard School of Public Health

BA, Swarthmore College

Publications

Published on 8/7/2026

Domanski MJ, Wu CO, Tian X, Shalhoub R, Miao R, Roney PC, Davis SN, Hasan AA, Reis JP, Bae S, Jacobs DR, Lloyd-Jones DM, Fuster V. Diabetes Mellitus, Cumulative Glucose Exposure, and Incident Cardiovascular Disease Risk. JACC Adv. 2026 Aug 07; 5(9):103087. PMID: 42567096.

Published on 8/1/2026

Wang N, DiCorpo DA, Zhang Y, Kleinbrink E, Arnett DK, Barnard J, Blangero J, Bowden DW, Carson AP, Chen YI, Chung MK, Curran JE, Darbar D, Duggirala R, Ellinor PT, Fatkin D, Fornage M, Heard-Costa N, He J, Hou L, Kardia SLR, Kooperberg C, Loos RJF, McManus DD, Mitchell BD, Minster RL, North KE, Psaty BM, Raffield LM, Redline S, Rich SS, Roden D, Rotter JI, Shoemaker MB, Smith JD, Van Wagoner DR, Aguet F, Ardlie K, Bis JC, Brody JA, Cade BE, Clish CB, de Vries PS, Floyd JS, Freedman BI, Gabriel S, Gerzsten RE, Goodarzi MO, Gu C, Guo X, Gupta N, Heckbert SR, Hsu S, Hung YJ, Kalyani RR, Kelly TN, Kinney GL, Li C, Liu S, Liu Y, Lloyd-Jones DM, Manson JE, Mathias RA, Mercader JM, Morrison AC, Naseri T, Onengut S, Palmer ND, Peyser PA, Qi Q, Raghavan S, Reiner AP, Rooney MR, Sevilla-Gonzalez M, Sarnowski C, Smith JD, Smith JA, Spartano NL, Tahir U, Taylor KD, Tobias DK, Tracy RP, Viali S, Wang H, Wood AC, Yanek LR, Zhao W, Zheng Y, Dupuis J, Liu CT, Sladek R, Wessel J, Meigs JB, Manning AK. Colocalization of eQTLs With Type 2 Diabetes and Glycemic Traits Using Whole-Genome Sequences in Diverse Populations From the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program. Diabetes. 2026 Aug 01; 75(8):1477-1491. PMID: 42274313.

Published on 7/1/2026

Bhatt SP, Sun Y, Wang Y, Balte PP, Schwartz JE, Cassano P, Chaves PH, Couper D, Jacobs DR, Kalhan R, Kaplan RC, Lloyd-Jones D, Newman AB, O'Connor GT, Sadatsafavi M, Umans JG, White WB, Yende S, Oelsner EC. Life Expectancy in Chronic Obstructive Pulmonary Disease. JAMA Intern Med. 2026 Jul 01; 186(7):852-860. PMID: 42143630.

Published on 6/22/2026

Blumenthal RS, Morris PB, Gaudino M, Johnson HM, Anderson TS, Bittner VA, Blankstein R, Brewer LC, Cho L, de Ferranti SD, Gianos E, Gluckman TJ, Gradney KF, Isiadinso I, Lloyd-Jones DM, Marrs JC, Martin SS, McLain KH, Mehta LS, Mora S, Mulugeta WM, Natarajan P, Navar AM, Orringer CE, Polonsky TS, Reynolds HR, Saseen JJ, Shapiro MD, Soffer DE, Tynes SA, Villavaso CD, Virani SS, Wilkins JT. Correction to: 2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2026 Jun 23; 153(25):e1447. PMID: 42330109.

Published on 6/15/2026

Goldman N, Allen NB, Pratt B, Ning H, Schneper L, Lloyd-Jones D, Notterman D. Authors Respond to "Racial and ethnic variation in socioeconomic differentials in young adult cardiovascular health". Am J Epidemiol. 2026 Jun 15. PMID: 42294593.

Published on 6/9/2026

Khan SS, Ndumele CE, Bhave N, Blumenthal RS, Coresh J, Huang X, Joseph JJ, Khera A, Ho JE, Lloyd-Jones DM, Low Wang CC, Lu Y, Morris PB, Nasir K, Natarajan P, Rangaswami J, Rodriguez F, Sperling LS, Virani SS, Zhang S. Use of Predicted Risk and Expected Benefit to Guide Decision-Making in Cardiovascular-Kidney-Metabolic Syndrome for the Primary Prevention of Cardiovascular Disease: A Scientific Statement From the American Heart Association and American College of Cardiology. J Am Coll Cardiol. 2026 Jun 09. PMID: 42263012.

Published on 6/9/2026

Khan SS, Bhave N, Blumenthal RS, Coresh J, Huang X, Joseph JJ, Khera A, Ho JE, Lloyd-Jones DM, Low Wang CC, Lu Y, Morris PB, Nasir K, Natarajan P, Rangaswami J, Rodriguez F, Sperling LS, Virani SS, Zhang S, Ndumele CE. Use of Predicted Risk and Expected Benefit to Guide Decision-Making in Cardiovascular-Kidney-Metabolic Syndrome for the Primary Prevention of Cardiovascular Disease: A Scientific Statement From the American Heart Association and American College of Cardiology. Circulation. 2026 Jul 28; 154(4):e159-e180. PMID: 42263147.

Published on 6/1/2026

Khan SS, Ndumele CE, Lloyd-Jones DM. Statin Eligibility According to Atherosclerotic Cardiovascular Disease Risk in the US-Reply. JAMA Cardiol. 2026 Jun 01; 11(6):610-611. PMID: 41920527.

Published on 6/1/2026

Khan SS, Huang X, Coresh J, Shah NS, Lloyd-Jones DM, Echouffo-Tcheugui JB, Matsushita K, Ndumele CE. Racial and Ethnic Differences in Predicted Cardiovascular Disease Risk Using the PREVENT Equations in the US Population. Circ Popul Health Outcomes. 2026 Jun 01; e012102. PMID: 42220236.

Published on 5/28/2026

Biola H, Davis J, Khan SS, Lloyd-Jones D, Pagidipati NJ, McDonald W, Moody M, O'Malley PG. Cardiovascular Risk Factors - Lifestyle Modifications. N Engl J Med. 2026 May 28; 394(20):e44. PMID: 42202317.

View full list of 874 publications.