David Richard Pimentel MD
Assistant Professor, Cardiovascular Medicine
650 Albany St | (617) 638-8146david.pimental@bmc.org
davidpim@bu.edu
Sections
Cardiovascular Medicine
Centers
Whitaker Cardiovascular Institute
Evans Center for Interdisciplinary Biomedical Research
Biography
Expertise includes: Oxidative modification; Exosomal communication.
Education
MD, University of Maryland School of Medicine
BA, University of Maryland
Publications
El Adili F, Moyo KM, Vo H, Kissin B, Yang J, Dinc MT, Browning J, Pimentel D, Fitzgibbons T, Slavin S, Qin F, Trojanowska M, Bujor AM. Down-Regulated Fli1 in Scleroderma Myeloid Cells Contributes to Cardiac Fibrosis Via a Galectin-3/mTOR Dependent Pathway. Arthritis Rheumatol. 2026 Sep 01. PMID: 42681974.
Published on 8/18/2026Yoo TK, Kaufman C, Pimentel DR, Hu TY, Rodriguez S, Franco P, Awtry EH, Pande AN, Gopal DM, Ayalon N. Direct Visualization of Acute Left Atrial Pressure Elevation During Atrioventricular Nodal Re-Entrant Tachycardia. JACC Case Rep. 2026 Oct 14; 31(41):109879. PMID: 42606396.
Published on 12/31/2025Valero-Muñoz M, Saw EL, Pimentel DR, Gower AC, Srinivasa S, Zanni MV, Toribio M, Grinspoon SK, Sam F. Molecular insights in HIV-associated cardiac dysfunction. Commun Med (Lond). 2025 Dec 31; 6(1):87. PMID: 41476135.
Published on 10/22/2025Baka T, Moore J, Qin F, Yurista SR, Zhang A, He H, Chambers JM, Croteau D, Goel RK, Smith H, Wang MC, Chen CS, Hobai IA, Rombaldova M, Kuda O, Tardiff JC, Balschi JA, Pimentel DR, Seidman CE, Seidman JG, Emili A, Colucci WS, Luptak I. Empagliflozin enhances metabolic efficiency and improves left ventricular hypertrophy in a hypertrophic cardiomyopathy mouse model. Eur Heart J. 2025 Oct 22; 46(40):4105-4119. PMID: 40396194.
Published on 5/8/2025Valero-Muñoz M, Saw EL, Cooper H, Pimentel DR, Sam F. White Adipose Tissue in Obesity-Associated HFpEF: Insights From Mice and Humans. JACC Basic Transl Sci. 2025 Aug; 10(8):101262. PMID: 40338771.
Published on 4/9/2025Chambers JM, Croteau D, Pimentel DR, Gower AC, Panagia M, Baka T, Qin F, Luptak I, Colucci WS. SGLT2 inhibitor upregulates myocardial genes for oxidative phosphorylation and fatty acid metabolism in Gaq-mice. J Mol Cell Cardiol Plus. 2025 Jun; 12:100296. PMID: 40291834.
Published on 6/13/2023Rucker DM, Siddiqi OK, Pimentel DR, Luptak I. Hemodynamic testing to guide vasodilator therapy in cardiac amyloidosis. J Cardiol Cases. 2023 Sep; 28(3):105-108. PMID: 37671260.
Published on 1/31/2023Croteau D, Baka T, Young S, He H, Chambers JM, Qin F, Panagia M, Pimentel DR, Balschi JA, Colucci WS, Luptak I. SGLT2 inhibitor ertugliflozin decreases elevated intracellular sodium, and improves energetics and contractile function in diabetic cardiomyopathy. Biomed Pharmacother. 2023 Apr; 160:114310. PMID: 36731341.
Published on 7/28/2021Mustafa Rizvi SH, Shao D, Tsukahara Y, Pimentel DR, Weisbrod RM, Hamburg NM, McComb ME, Matsui R, Bachschmid MM. Oxidized GAPDH transfers S-glutathionylation to a nuclear protein Sirtuin-1 leading to apoptosis. Free Radic Biol Med. 2021 10; 174:73-83. PMID: 34332079.
Published on 6/25/2021Croteau D, Luptak I, Chambers JM, Hobai I, Panagia M, Pimentel DR, Siwik DA, Qin F, Colucci WS. Effects of Sodium-Glucose Linked Transporter 2 Inhibition With Ertugliflozin on Mitochondrial Function, Energetics, and Metabolic Gene Expression in the Presence and Absence of Diabetes Mellitus in Mice. J Am Heart Assoc. 2021 07 06; 10(13):e019995. PMID: 34169737.