David Richard Pimentel MD

Assistant Professor, Cardiovascular Medicine

650 Albany St | (617) 638-8146
DP
Sections

Cardiovascular Medicine

Centers

Whitaker Cardiovascular Institute

Evans Center for Interdisciplinary Biomedical Research

Biography

Expertise includes: Oxidative modification; Exosomal communication.

Education

MD, University of Maryland School of Medicine

BA, University of Maryland

Publications

Published on 9/1/2026

El Adili F, Moyo KM, Vo H, Kissin B, Yang J, Dinc MT, Browning J, Pimentel D, Fitzgibbons T, Slavin S, Qin F, Trojanowska M, Bujor AM. Down-Regulated Fli1 in Scleroderma Myeloid Cells Contributes to Cardiac Fibrosis Via a Galectin-3/mTOR Dependent Pathway. Arthritis Rheumatol. 2026 Sep 01. PMID: 42681974.

Published on 8/18/2026

Yoo TK, Kaufman C, Pimentel DR, Hu TY, Rodriguez S, Franco P, Awtry EH, Pande AN, Gopal DM, Ayalon N. Direct Visualization of Acute Left Atrial Pressure Elevation During Atrioventricular Nodal Re-Entrant Tachycardia. JACC Case Rep. 2026 Oct 14; 31(41):109879. PMID: 42606396.

Published on 12/31/2025

Valero-Muñoz M, Saw EL, Pimentel DR, Gower AC, Srinivasa S, Zanni MV, Toribio M, Grinspoon SK, Sam F. Molecular insights in HIV-associated cardiac dysfunction. Commun Med (Lond). 2025 Dec 31; 6(1):87. PMID: 41476135.

Published on 10/22/2025

Baka T, Moore J, Qin F, Yurista SR, Zhang A, He H, Chambers JM, Croteau D, Goel RK, Smith H, Wang MC, Chen CS, Hobai IA, Rombaldova M, Kuda O, Tardiff JC, Balschi JA, Pimentel DR, Seidman CE, Seidman JG, Emili A, Colucci WS, Luptak I. Empagliflozin enhances metabolic efficiency and improves left ventricular hypertrophy in a hypertrophic cardiomyopathy mouse model. Eur Heart J. 2025 Oct 22; 46(40):4105-4119. PMID: 40396194.

Published on 5/8/2025

Valero-Muñoz M, Saw EL, Cooper H, Pimentel DR, Sam F. White Adipose Tissue in Obesity-Associated HFpEF: Insights From Mice and Humans. JACC Basic Transl Sci. 2025 Aug; 10(8):101262. PMID: 40338771.

Published on 4/9/2025

Chambers JM, Croteau D, Pimentel DR, Gower AC, Panagia M, Baka T, Qin F, Luptak I, Colucci WS. SGLT2 inhibitor upregulates myocardial genes for oxidative phosphorylation and fatty acid metabolism in Gaq-mice. J Mol Cell Cardiol Plus. 2025 Jun; 12:100296. PMID: 40291834.

Published on 6/13/2023

Rucker DM, Siddiqi OK, Pimentel DR, Luptak I. Hemodynamic testing to guide vasodilator therapy in cardiac amyloidosis. J Cardiol Cases. 2023 Sep; 28(3):105-108. PMID: 37671260.

Published on 1/31/2023

Croteau D, Baka T, Young S, He H, Chambers JM, Qin F, Panagia M, Pimentel DR, Balschi JA, Colucci WS, Luptak I. SGLT2 inhibitor ertugliflozin decreases elevated intracellular sodium, and improves energetics and contractile function in diabetic cardiomyopathy. Biomed Pharmacother. 2023 Apr; 160:114310. PMID: 36731341.

Published on 7/28/2021

Mustafa Rizvi SH, Shao D, Tsukahara Y, Pimentel DR, Weisbrod RM, Hamburg NM, McComb ME, Matsui R, Bachschmid MM. Oxidized GAPDH transfers S-glutathionylation to a nuclear protein Sirtuin-1 leading to apoptosis. Free Radic Biol Med. 2021 10; 174:73-83. PMID: 34332079.

Published on 6/25/2021

Croteau D, Luptak I, Chambers JM, Hobai I, Panagia M, Pimentel DR, Siwik DA, Qin F, Colucci WS. Effects of Sodium-Glucose Linked Transporter 2 Inhibition With Ertugliflozin on Mitochondrial Function, Energetics, and Metabolic Gene Expression in the Presence and Absence of Diabetes Mellitus in Mice. J Am Heart Assoc. 2021 07 06; 10(13):e019995. PMID: 34169737.

View full list of 75 publications.