David T. Felson MD, MPH

Professor, Rheumatology

Professor, Epidemiology

650 Albany St | (617) 638-5180
David Felson



Arthritis & Autoimmune Diseases Research Center

Framingham Heart Study

Boston Nutrition Obesity Research Center

Evans Center for Interdisciplinary Biomedical Research


Dr. David Felson's research interests include: understanding how to prevent osteoarthritis and treat osteoarthritis. In osteoarthritis, Dr. Felson’s interests include studying whether treatments for rheumatic diseases are effective and particularly in osteoarthritis, identifying biomechanical risk factors for disease and testing biomechanical treatments and characterizing MRI features of normal knees and knees with pain. He also studies outcome measurement in rheumatic disease and has focused in this work on rheumatoid arthritis trials.

Other Positions


Medicine, MD, Johns Hopkins University, 1978

Public Health, MPH, Boston University School of Public Health, 1984

History/Biochemistry, AB, Harvard College, 1971


Published on 9/1/2022

Jafarzadeh SR, Neogi T, White DK, Felson DT. The Relationship of Pain Reduction With Prevention of Knee Replacement Under Dynamic Intervention Strategies. Arthritis Rheumatol. 2022 Oct; 74(10):1668-1675. PMID: 35726122.

Published on 7/19/2022

Zertuche JP, Rabasa G, Lichtenstein AH, Matthan NR, Nevitt M, Torner J, Lewis CE, Dai Z, Misra D, Felson D. Alkylresorcinol, a biomarker for whole grain intake, and its association with osteoarthritis: the MOST study. Osteoarthritis Cartilage. 2022 Oct; 30(10):1337-1343. PMID: 35863678.

Published on 7/14/2022

Kim JS, Borges S, Clauw DJ, Conaghan PG, Felson DT, Fleming TR, Glaser R, Hart E, Hochberg M, Kim Y, Kraus VB, Lapteva L, Li X, Majumdar S, McAlindon TE, Mobasheri A, Neogi T, Roemer FW, Rothwell R, Shibuya R, Siegel J, Simon LS, Spindler KP, Nikolov NP. FDA/Arthritis Foundation osteoarthritis drug development workshop recap: Assessment of long-term benefit. Semin Arthritis Rheum. 2022 Oct; 56:152070. PMID: 35870222.

Published on 6/11/2022

Carlesso LC, Jafarzadeh SR, Stokes A, Felson DT, Wang N, Frey-Law L, Lewis CE, Nevitt M, Neogi T. Depressive symptoms and multi-joint pain partially mediate the relationship between obesity and opioid use in people with knee osteoarthritis. Osteoarthritis Cartilage. 2022 Sep; 30(9):1263-1269. PMID: 35700904.

Published on 6/1/2022

Felson D, Feathers V, Naik C, Solomon DH, Weinblatt ME, Shadick N. Meaning of patient global assessment when joint counts are low in rheumatoid arthritis. RMD Open. 2022 Jun; 8(2). PMID: 35738804.

Published on 4/7/2022

Liu M, Huang Y, Zhang H, Aitken D, Nevitt MC, Rockel JS, Pelletier JP, Lewis CE, Torner J, Rampersaud YR, Perruccio AV, Mahomed NN, Furey A, Randell EW, Rahman P, Sun G, Martel-Pelletier J, Kapoor M, Jones G, Felson D, Qi D, Zhai G. Restricting Branched-Chain Amino Acids within a High-Fat Diet Prevents Obesity. Metabolites. 2022 Apr 07; 12(4). PMID: 35448521.

Published on 3/18/2022

Murphy MT, Wang N, Felson DT, Nevitt MC, Lewis CE, Frey-Law L, Guermazi A, Segal NA. Association between hamstring coactivation during isokinetic quadriceps strength testing and knee cartilage worsening over 24 months. Osteoarthritis Cartilage. 2022 Jun; 30(6):823-831. PMID: 35307535.

Published on 3/10/2022

Gates LS, Perry TA, Golightly YM, Nelson AE, Callahan LF, Felson D, Nevitt M, Jones G, Cooper C, Batt ME, Sanchez-Santos MT, Arden NK. Recreational Physical Activity and Risk of Incident Knee Osteoarthritis: An International Meta-Analysis of Individual Participant-Level Data. Arthritis Rheumatol. 2022 04; 74(4):612-622. PMID: 34730279.

Published on 3/4/2022

Liew JW, Peloquin C, Tedeschi SK, Felson DT, Zhang Y, Choi HK, Terkeltaub R, Neogi T. Proton-Pump Inhibitors and Risk of Calcium Pyrophosphate Deposition in a Population-Based Study. Arthritis Care Res (Hoboken). 2022 Mar 04. PMID: 35245410.

Published on 2/22/2022

Roemer FW, Felson DT, Stefanik JJ, Rabasa G, Wang N, Crema MD, Neogi T, Nevitt MC, Torner J, Lewis CE, Peloquin C, Guermazi A. Heterogeneity of cartilage damage in Kellgren and Lawrence grade 2 and 3 knees: the MOST study. Osteoarthritis Cartilage. 2022 May; 30(5):714-723. PMID: 35202808.

View full list of 969 publications.