Chunlei Zheng PhD
Voluntary Assistant Professor, General Internal Medicine
801 Massachusetts Ave | (216) 482-5101chunleiz@bu.edu
Sections
General Internal Medicine
Biography
Chunlei Zheng is an Assistant Professor of Medicine at Chobanian and Avedisian School of Medicine. He is also a Health Science Specialist at VA Boston Healthcare System. Dr. Zheng completed his PhD in Biophysics at Chinese Academy of Sciences. After graduation, he moved to Cleveland Clinic, where he received a postdoctoral fellowship from American Heart Association to study the protein trafficking in human diseases. Before joining Boston University, Dr. Zheng is a research scientist at Case Western Reserve University, where he received intensive biomedical informatics training.
With solid background in biology and medicine and expertise in genomics, computer science, and statistics, Dr. Zheng has great passion for data-driven biomedical discovery. In particular, he has great interest on developing/applying computational algorithm, machine learning and statistical modeling into large-scale biomedical data to facilitate disease understanding and drug discovery. Currently, his research focuses on using artificial intelligence (AI) on Alzheimer’s Disease and Cancer.
Education
PhD, Chinese Academy of Sciences, 2007
Biology, BS, Shaanxi Normal University, 1997
Publications
Placido D, Yuan B, Hjaltelin JX, Zheng C, Haue AD, Chmura PJ, Yuan C, Kim J, Umeton R, Antell G, Chowdhury A, Franz A, Brais L, Andrews E, Marks DS, Regev A, Ayandeh S, Brophy MT, Do NV, Kraft P, Wolpin BM, Rosenthal MH, Fillmore NR, Brunak S, Sander C. A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories. Nat Med. 2023 May; 29(5):1113-1122. PMID: 37156936.
Published on 1/19/2022Li LL, Zheng C, La J, Do NV, Monach PA, Strymish JM, Fillmore NR, Branch-Elliman W. Impact of prior SARS-CoV-2 infection on incidence of hospitalization and adverse events following mRNA SARS-CoV-2 vaccination: A nationwide, retrospective cohort study. Vaccine. 2022 02 16; 40(8):1082-1089. PMID: 35078665.
Published on 1/11/2022Fillmore NR, La J, Zheng C, Doron S, Do NV, Monach PA, Branch-Elliman W. The COVID-19 hospitalization metric in the pre- and postvaccination eras as a measure of pandemic severity: A retrospective, nationwide cohort study. Infect Control Hosp Epidemiol. 2022 Dec; 43(12):1767-1772. PMID: 35012694.
Published on 9/27/2021Zheng C, Fillmore NR, Ramos-Cejudo J, Brophy M, Osorio R, Gurney ME, Qiu WQ, Au R, Perry G, Dubreuil M, Chen SG, Qi X, Davis PB, Do N, Xu R. Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans. Alzheimers Dement. 2022 Jun; 18(6):1248-1259. PMID: 34569707.
Published on 5/20/2021Zheng C, Xu R. Molecular subtyping of Alzheimer's disease with consensus non-negative matrix factorization. PLoS One. 2021; 16(5):e0250278. PMID: 34014928.
Published on 1/25/2021Wang Q, Li Y, Zheng C, Xu R. DenseCNN: A Densely Connected CNN Model for Alzheimer's Disease Classification Based on Hippocampus MRI Data. AMIA Annu Symp Proc. 2020; 2020:1277-1286. PMID: 33936504.
Published on 1/11/2021Zhou M, Wang Q, Zheng C, John Rush A, Volkow ND, Xu R. Drug repurposing for opioid use disorders: integration of computational prediction, clinical corroboration, and mechanism of action analyses. Mol Psychiatry. 2021 09; 26(9):5286-5296. PMID: 33432189.
Published on 7/21/2020Zheng C, Berger NA, Li L, Xu R. Epigenetic age acceleration and clinical outcomes in gliomas. PLoS One. 2020; 15(7):e0236045. PMID: 32692766.
Published on 7/1/2020Zhou M, Zheng C, Xu R. Combining phenome-driven drug-target interaction prediction with patients' electronic health records-based clinical corroboration toward drug discovery. Bioinformatics. 2020 07 01; 36(Suppl_1):i436-i444. PMID: 32657406.
Published on 5/8/2020Zheng C, Xu R. Predicting cancer origins with a DNA methylation-based deep neural network model. PLoS One. 2020; 15(5):e0226461. PMID: 32384093.