Carlos Jesus Acuna-Villaorduna MD

Adjunct Assistant Professor, Infectious Diseases

650 Albany St | (617) 414-5231
caacunav@bu.edu
carlos.acuna-villaorduna@bmc.org

Sections

Infectious Diseases

Biography

Dr. Carlos Acuña-Villaorduña is an infectious disease specialist with interest in tuberculosis, tropical medicine, and mathematical modelling of infectious diseases. After finishing medical school, he worked as a researcher at the “Alexander Von Humboldt Tropical Medicine Institute” in Lima, Peru, the largest tropical medicine in South America, where he successfully collaborated in several research projects in tuberculosis epidemiology and diagnostics. After moving to the United States to complete his medical training, he earned a master degree in epidemiology at the “University of London”. He currently holds an appointment as Assistant Professor of Medicine at Boston University and provide care for patients at the tuberculosis clinic of Boston. Dr. Acuña-Villaorduña is interested in understanding the complex mechanisms leading to tuberculosis transmission in developing countries. His research focuses on investigating the ability of certain mycobacterial strains to survive in the environment and to produce infection and disease.

Websites

Education

Medicine-Internal, MD, Universidad Peruana Cayetano Heredia

Publications

Published on 1/5/2023

Hamada Y, Gupta RK, Quartagno M, Izzard A, Acuna-Villaorduna C, Altet N, Diel R, Dominguez J, Floyd S, Gupta A, Huerga H, Jones-López EC, Kinikar A, Lange C, van Leth F, Liu Q, Lu W, Lu P, Rueda IL, Martinez L, Mbandi SK, Muñoz L, Padilla ES, Paradkar M, Scriba T, Sester M, Shanaube K, Sharma SK, Sloot R, Sotgiu G, Thiruvengadam K, Vashishtha R, Abubakar I, Rangaka MX. Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis. EClinicalMedicine. 2023 Feb; 56:101815. PMID: 36636295.

PubMed

Published on 9/10/2022

Sinha P, Lakshminarayanan SL, Cintron C, Narasimhan PB, Locks LM, Kulatilaka N, Maloomian K, Prakash Babu S, Carwile ME, Liu AF, Horsburgh CR, Acuna-Villaorduna C, Linas BP, Hochberg NS. Nutritional Supplementation Would Be Cost-Effective for Reducing Tuberculosis Incidence and Mortality in India: The Ration Optimization to Impede Tuberculosis (ROTI-TB) Model. Clin Infect Dis. 2022 Sep 10; 75(4):577-585. PMID: 34910141.

PubMed

Published on 9/1/2022

Martinez L, Cords O, Liu Q, Acuna-Villaorduna C, Bonnet M, Fox GJ, Carvalho ACC, Chan PC, Croda J, Hill PC, Lopez-Varela E, Donkor S, Fielding K, Graham SM, Espinal MA, Kampmann B, Reingold A, Huerga H, Villalba JA, Grandjean L, Sotgiu G, Egere U, Singh S, Zhu L, Lienhardt C, Denholm JT, Seddon JA, Whalen CC, García-Basteiro AL, Triasih R, Chen C, Singh J, Huang LM, Sharma S, Hannoun D, Del Corral H, Mandalakas AM, Malone LL, Ling DL, Kritski A, Stein CM, Vashishtha R, Boulahbal F, Fang CT, Boom WH, Netto EM, Lemos AC, Hesseling AC, Kay A, Jones-López EC, Horsburgh CR, Lange C, Andrews JR. Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis. Lancet Glob Health. 2022 Sep; 10(9):e1307-e1316. PMID: 35961354.

PubMed

Published on 2/5/2022

Dhanani M, Goodrich C, Weinberg J, Acuna-Villaorduna C, Barlam TF. Antibiotic therapy completion for injection drug use-associated infective endocarditis at a center with routine addiction medicine consultation: a retrospective cohort study. BMC Infect Dis. 2022 Feb 05; 22(1):128. PMID: 35123439.

PubMed

Published on 9/21/2020

Sinha P, Carwile M, Bhargava A, Cintron C, Acuna-Villaorduna C, Lakshminarayan S, Liu AF, Kulatilaka N, Locks L, Hochberg NS. How much do Indians pay for tuberculosis treatment? A cost analysis. Public Health Action. 2020 Sep 21; 10(3):110-117. PMID: 33134125.

PubMed

Published on 10/31/2019

Fennelly KP, Acuna-Villaorduna C, Jones-Lopez E, Lindsley WG, Milton DK. Microbial Aerosols: New Diagnostic Specimens for Pulmonary Infections. Chest. 2020 03; 157(3):540-546. PMID: 31678308.

PubMed

Published on 4/11/2019

Acuña-Villaorduña C, Ayakaka I, Schmidt-Castellani LG, Mumbowa F, Marques-Rodrigues P, Gaeddert M, White LF, Palaci M, Ellner JJ, Dietze R, Joloba M, Fennelly KP, Jones-López EC. Host Determinants of Infectiousness in Smear-Positive Patients With Pulmonary Tuberculosis. Open Forum Infect Dis. 2019 Jun; 6(6):ofz184. PMID: 31205972.

PubMed

Published on 10/29/2018

Acuña-Villaorduña C, Schmidt-Castellani LG, Marques-Rodrigues P, White LF, Hadad DJ, Gaeddert M, Ellner JJ, Fennelly KP, Palaci M, Dietze R, Jones-López EC. Cough-aerosol cultures of Mycobacterium tuberculosis in the prediction of outcomes after exposure. A household contact study in Brazil. PLoS One. 2018; 13(10):e0206384. PMID: 30372480.

PubMed

Published on 7/13/2018

Geadas C, Acuna-Villaorduna C, Mercier G, Kleinman MB, Horsburgh CR, Ellner JJ, Jacobson KR. FDG-PET/CT activity leads to the diagnosis of unsuspected TB: a retrospective study. BMC Res Notes. 2018 Jul 13; 11(1):464. PMID: 30001743.

PubMed

Published on 1/18/2018

Acuña-Villaorduña C, Jones-López EC, Fregona G, Marques-Rodrigues P, Gaeddert M, Geadas C, Hadad DJ, White LF, Pereira Dutra Molina L, Vinhas S, Ribeiro-Rodrigues R, Salgame P, Palaci M, Alland D, Ellner JJ, Dietze R. Intensity of exposure to pulmonary tuberculosis determines risk of tuberculosis infection and disease. Eur Respir J. 2018 01; 51(1). PMID: 29348181.

PubMed

View full list of 22 publications.