Barbara E. Corkey PhD

Professor Emeritus, Endocrinology, Diabetes, Nutrition & Weight Management

Zoltan Kohn Professor, Medicine

650 Albany St | (617) 638-7091
Barbara Corkey
Sections

Endocrinology, Diabetes, Nutrition & Weight Management

Centers

Boston Nutrition Obesity Research Center

Evans Center for Interdisciplinary Biomedical Research

Biography

Dr. Barbara Corkey is Emeritus Professor of Medicine and Biochemistry. Dr. Corkey’s work focuses on the metabolic regulation of signal transduction and energy metabolism in fat cells, β-cells, and human fibroblasts. She and her colleagues have been studying fuel-stimulated insulin secretion by the pancreatic β-cell; fuel partitioning in rat adipocytes; cytokine signaling; and Ca2+ transients in human fibroblasts from patients with inborn errors of fatty acid oxidation and Type 1 diabetes.

Other Positions

Education

PhD, University of Pennsylvania School of Medicine, 1981

Publications

Published on 6/20/2022

Merrins MJ, Corkey BE, Kibbey RG, Prentki M. Metabolic cycles and signals for insulin secretion. Cell Metab. 2022 Jul 05; 34(7):947-968. PMID: 35728586.

Published on 11/12/2021

Schwartz SS, Rachfal AW, Corkey BE. The time is now for new, lower diabetes diagnostic thresholds. Trends Endocrinol Metab. 2022 01; 33(1):4-7. PMID: 34776305.

Published on 10/1/2021

Corkey BE, Deeney JT, Merrins MJ. What Regulates Basal Insulin Secretion and Causes Hyperinsulinemia? Diabetes. 2021 10; 70(10):2174-2182. PMID: 34593535.

Published on 9/27/2021

Istfan N, Hasson B, Apovian C, Meshulam T, Yu L, Anderson W, Corkey BE. Acute carbohydrate overfeeding: a redox model of insulin action and its impact on metabolic dysfunction in humans. Am J Physiol Endocrinol Metab. 2021 11 01; 321(5):E636-E651. PMID: 34569273.

Published on 4/6/2021

Roth J, Ashcroft FM, Wollheim CB, Kieffer TJ, Cherrington AD, Bergman RN, Taylor R, Najjar SM, Pedersen O, Ellingsgaard H, Holst JJ, Nauck MA, Kadowaki T, Czech MP, Corvera S, Saltiel AR, Corkey BE, Atkinson MA. Voices: Insulin and beyond. Cell Metab. 2021 04 06; 33(4):692-699. PMID: 33826910.

Published on 12/3/2020

Veliova M, Ferreira CM, Benador IY, Jones AE, Mahdaviani K, Brownstein AJ, Desousa BR, Acín-Pérez R, Petcherski A, Assali EA, Stiles L, Divakaruni AS, Prentki M, Corkey BE, Liesa M, Oliveira MF, Shirihai OS. Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling. EMBO Rep. 2020 12 03; 21(12):e49634. PMID: 33275313.

Published on 11/3/2020

Corkey BE. Targeting Pyruvate Kinase PEPs Up Insulin Secretion and Improves Glucose Homeostasis. Cell Metab. 2020 11 03; 32(5):693-694. PMID: 33147479.

Published on 10/15/2020

Corkey BE, Deeney JT. The Redox Communication Network as a Regulator of Metabolism. Front Physiol. 2020; 11:567796. PMID: 33178037.

Published on 1/22/2020

Rumala CZ, Liu J, Locasale JW, Corkey BE, Deeney JT, Rameh LE. Exposure of Pancreatic ß-Cells to Excess Glucose Results in Bimodal Activation of mTORC1 and mTOR-Dependent Metabolic Acceleration. iScience. 2020 Feb 21; 23(2):100858. PMID: 32058969.

Published on 12/23/2019

Thomas DD, Stockman MC, Yu L, Meshulam T, McCarthy AC, Ionson A, Burritt N, Deeney J, Cabral H, Corkey B, Istfan N, Apovian CM. Effects of medium chain triglycerides supplementation on insulin sensitivity and beta cell function: A feasibility study. PLoS One. 2019; 14(12):e0226200. PMID: 31869355.

View full list of 257 publications.