Aruna Pradhan MD
Adjunct Assistant Professor, Cardiovascular Medicine
72 E. Concord Street
An associate epidemiologist, cardiologist, and Assistant Professor of Medicine at Harvard Medical School, Dr. Pradhan joined CIRT in 2005. She has joint appointments in the Division of Preventive Medicine at the Brigham and Women’s Hospital and Cardiovascular Medicine Division at the Veteran’s Administration Hospital, West Roxbury Campus. Her research interests span the related areas of inflammation, diabetes, and peripheral artery disease. Her early work demonstrated a strong link between subclinical inflammation and the development of diabetes. She continued this line of research as the Principal Investigator of the LANCET clinical trial which studied insulin therapy as a strategy to reduce inflammation among patients with diabetes during the initial stage of this disease. Other research activities pertain to the role of adipokines and other biologic markers having combined metabolic and inflammatory functions in the pathogenesis of diabetes and its vascular complications. As a recipient of a career development award from the National Heart, Lung, and Blood Institute to study risk factors for peripheral artery disease, Dr. Pradhan is also keenly interested in evaluating risk factors and underlying mechanisms that distinguish individuals at high risk for future coronary artery disease as compared to lower extremity artery disease. Dr. Pradhan is also a recipient of NIH funding to evaluate mechanisms of statin-associated diabetes in the JUPITER trial.
Dr. Pradhan completed her cardiovascular medicine fellowship at the Brigham and Women’s Hospital and continues her clinical activities as an echocardiographer and clinical cardiologist at the VA Boston Healthcare System, West Roxbury Campus.
MD, Georgetown University School of Medicine, 1996
Epidemiology, MSc, Harvard School of Public Health, 2001
International Health, MPH, Johns Hopkins University School of Public Health, 1995
Chemistry, BS, Georgetown University, 1990
Malick WA, Waksman O, Do R, Koenig W, Pradhan AD, Stroes ESG, Rosenson RS. Clinical Trial Design for Triglyceride-Rich Lipoprotein-Lowering Therapies: JACC Focus Seminar 3/3. J Am Coll Cardiol. 2023 Apr 25; 81(16):1646-1658. PMID: 37076219.Published on 3/6/2023
Ridker PM, Bhatt DL, Pradhan AD, Glynn RJ, MacFadyen JG, Nissen SE. Inflammation and cholesterol as predictors of cardiovascular events among patients receiving statin therapy: a collaborative analysis of three randomised trials. Lancet. 2023 Apr 15; 401(10384):1293-1301. PMID: 36893777.Published on 12/21/2022
Taqueti VR, Shah AM, Everett BM, Pradhan AD, Piazza G, Bibbo C, Hainer J, Morgan V, Carolina do A H de Souza A, Skali H, Blankstein R, Dorbala S, Goldhaber SZ, Le May MR, Chow BJW, deKemp RA, Hage FG, Beanlands RS, Libby P, Glynn RJ, Solomon SD, Ridker PM, Di Carli MF. Coronary Flow Reserve, Inflammation, and Myocardial Strain: The CIRT-CFR Trial. JACC Basic Transl Sci. 2023 Feb; 8(2):141-151. PMID: 36908662.Published on 6/18/2022
Bartoli-Leonard F, Turner ME, Zimmer J, Chapurlat R, Pham T, Aikawa M, Pradhan AD, Szulc P, Aikawa E. Elevated lipoprotein(a) as a predictor for coronary events in older men. J Lipid Res. 2022 Aug; 63(8):100242. PMID: 35724702.Published on 7/21/2021
Pradhan AD. Time to commence or time out for colchicine in secondary prevention of cardiovascular disease? Eur Heart J. 2021 07 21; 42(28):2776-2779. PMID: 33824963.Published on 6/18/2021
Levin MG, Zuber V, Walker VM, Klarin D, Lynch J, Malik R, Aday AW, Bottolo L, Pradhan AD, Dichgans M, Chang KM, Rader DJ, Tsao PS, Voight BF, Gill D, Burgess S, Damrauer SM. Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease. Circulation. 2021 08 03; 144(5):353-364. PMID: 34139859.Published on 5/27/2021
Aday AW, Duran EK, Van Denburgh M, Kim E, Christen WG, Manson JE, Ridker PM, Pradhan AD. Homocysteine Is Associated With Future Venous Thromboembolism in 2 Prospective Cohorts of Women. Arterioscler Thromb Vasc Biol. 2021 07; 41(7):2215-2224. PMID: 34039021.Published on 1/8/2021
Duran EK, Pradhan AD. Triglyceride-Rich Lipoprotein Remnants and Cardiovascular Disease. Clin Chem. 2021 01 08; 67(1):183-196. PMID: 33409533.Published on 5/5/2020
Duran EK, Aday AW, Cook NR, Buring JE, Ridker PM, Pradhan AD. Triglyceride-Rich Lipoprotein Cholesterol, Small Dense LDL Cholesterol, and Incident Cardiovascular Disease. J Am Coll Cardiol. 2020 05 05; 75(17):2122-2135. PMID: 32354380.Published on 4/13/2020
Pradhan AD, Aday AW, Beckman JA. The Big MAC Attack on Peripheral Artery Disease. Circulation. 2020 04 14; 141(15):1211-1213. PMID: 32282252.