Anica Law MD, MS, ATSF

Assistant Professor, Pulmonary, Allergy, Sleep & Critical Care Medicine

72 East Concord Street | (617) 358-2800
Anica Law
Sections

Pulmonary, Allergy, Sleep & Critical Care Medicine

Biography

Dr. Law is a Pulmonary and Critical Care physician, clinical epidemiologist, and health services researcher with a focus on understanding determinants of outcomes after critical illness. An unprecedented number of patients now survive the intensive care unit (ICU) but suffer severe organ dysfunction, requiring forms of long-term organ support, such as mechanical ventilation or artificial nutrition. Using both granular clinical and national claims databases, and leveraging natural experiments where feasible (e.g., policy changes), the goal of her research is to better inform decision-making during critical illness and the optimal delivery of care after acute critical illness.

She has published > 70 original studies in high-impact journals including JAMA, JAMA Internal Medicine, JAMA Network Open, AJRCCM, and Annals of Internal Medicine. Her work has been included in the Top Papers” in the ATS Clinical Year in Review (2023, 2024), and covered by media outlets such as NPR, U.S. News & World Report, and the Associated Press. Her NIA-funded F32 and NHLBI-funded K23 characterized national practices and outcomes for patients receiving long-term feeding and breathing tubes during critical illness. These studies demonstrated (1) poor patient-centered outcomes after receipt of feeding/breathing tubes and (2) unexpected declines in incidence of prolonged mechanical ventilation with increases in palliative care and hospice among Medicare beneficiaries—trends that diverged from earlier projections. She also showed that Medicare payment reforms substantially reduced access to long-term acute care hospitals (LTACHs), leading to increased use of do-not-resuscitate orders and lower costs to Medicare, highlighting how policy shifts influence upstream care decisions and post-acute resource use. She now helms an R01, "Quantifying Uncertainty to Inform Time-Limited Trials of Invasive Mechanical Ventilation" (scored in the 1st percentile at NIH/NHLBI), which seeks to improve patient and family engagement in early prognostication for mechanically ventilated patients.

Education

MD, University of Pennsylvania School of Medicine

MS, Harvard School of Public Health

Biology, AB, Harvard College

Publications

Published on 6/1/2026

Law AC, Bosch NA, Song Y, Tale AP, Nelson J, Wadhera RK, Barnato AE, Walkey AJ. Improved agreement between in-hospital and time-delimited mortality by including hospice discharges. Ann Am Thorac Soc. 2026 Jun 01; 23(6):998-1000. PMID: 41849433.

Published on 5/1/2026

Law AC, Bosch NA, Song Y, Tale AP, Nelson J, Wadhera RK, Barnato AE, Walkey AJ. Trends in discharge to hospice after critical illness among US Medicare beneficiaries, 2011-2023. Ann Am Thorac Soc. 2026 May 01; 23(5):815-818. PMID: 41705500.

Published on 4/1/2026

Bhuiya S, Teja B, Law AC, Gershengorn H, Iwashyna TJ, Vail E, Walkey AJ, Wunsch H, Bosch NA. Vasoactive regimens and outcomes in patients with septic shock: an observational cohort study. Ann Am Thorac Soc. 2026 Apr 01; 23(4):662-665. PMID: 41915563.

Published on 3/1/2026

Shi Z, Bosch NA, Heckman EJ, Gershengorn HB, Shankar DA, Law AC. Validation of a charge-based algorithm for identifying days receiving invasive mechanical ventilation. Ann Am Thorac Soc. 2026 Mar 01; 23(3):464-467. PMID: 41842742.

Published on 2/23/2026

Law AC, Kruser JM. Measuring Uncertainty to Inform Time-Limited Trials: Do We Know What We Don't Know? Crit Care Med. 2026 Apr 01; 54(4):1013-1016. PMID: 41729054.

Published on 2/4/2026

Berube M, Bortman JM, Law AC, Bosch NA. Haemoglobin threshold-based blood transfusion practices in patients following hip fracture surgery: a multicentre retrospective study. Hip Int. 2026 Feb 04; 11207000251409092. PMID: 41636050.

Published on 2/1/2026

Li B, Gershengorn HB, Vail EA, Wunsch H, Walkey AJ, Law AC, Ko D, Ayalon N, Kearney CM, Bosch NA. Inotrope selection in mixed cardiogenic shock with sepsis: a comparative analysis between milrinone and dobutamine. Ann Am Thorac Soc. 2026 Feb 01; 23(2):252-260. PMID: 40960311.

Published on 1/26/2026

Feeney ME, Canova AE, Law AC, Walkey AJ, Bosch NA. Guideline-Concordant Sedative and Analgesia Use in Critically Ill Patients Receiving Sustained Neuromuscular Blockade. Crit Care Explor. 2026 Feb 01; 8(2):e1370. PMID: 41586742.

Published on 12/12/2025

Shankar DA, Bosch NA, Jafarzadeh SR, Drainoni ML, Wiener RS, Wilson KC, Hawkins FJ, Alysandratos KD, Walkey AJ, Law AC. Association of Pulse Dose Corticosteroids With Outcomes Among Patients With Acute Exacerbations of Idiopathic Pulmonary Fibrosis. CHEST Pulm. 2025 Dec; 3(4). PMID: 41503513.

Published on 10/27/2025

Shen BH, Shankar DA, Bosch NA, Walkey AJ, Piazza G, Klings ES, Law AC. Contemporary reperfusion therapies in patients with intermediate- and high-risk pulmonary embolism. Thromb Res. 2025 Dec; 256:109523. PMID: 41175547.

View full list of 92 publications.