Andrew Berical MD

Published on 10/15/2026

Zhou H, Terbeck L, Berical A, Brunet M, Lange SM, Anderson JR, Olbrich H, Bracht DC, Wohlgemuth K, Rieck C, Raidt J, Klingauf J, Sutharsan S, Mussaffi H, Prais D, Dunphy V, Homma ST, Guichard P, Hamel V, Hawkins FJ, Omran H, Brown A. In situ structure of the human ciliary transition zone links linker defects to primary ciliary dyskinesia. Science. 2026 Oct 15; 394(6821):eaei5957. PMID: 42721274.

Published on 7/31/2025

Wallman DJ, Homma ST, Finton M, Beermann M, Jacob A, Choksi SP, Pletcher SD, Xu H, Bawa PS, Reiter JF, Horani A, Brody SL, Berical A, Hawkins FJ. A stem cell-based platform for functional analysis of genetic variants in lung disease. bioRxiv. 2025 Jul 31. PMID: 40766356.

Published on 5/1/2025

Berical AC, Kiyokawa H, Beermann ML, Wallman D, Cherfane G, Dunphy V, Pan J, Tilston-Lunel A, Varelas X, Horani A, Brody SL, Kotton DN, Hawkins FJ. Reply to Huang et al.: Sowing Tailored Seeds: Gene-edited Basal Cells for Precision Regulation of Airway Phenotypes. Am J Respir Crit Care Med. 2025 May; 211(5):884. PMID: 39999444.

Published on 1/29/2025

Brody SL, Pan J, Huang T, Xu J, Xu H, Koenitizer JR, Brennan SK, Nanjundappa R, Saba TG, Rumman N, Berical A, Hawkins FJ, Wang X, Zhang R, Mahjoub MR, Horani A, Dutcher SK. Undocking of an extensive ciliary network induces proteostasis and cell fate switching resulting in severe primary ciliary dyskinesia. Sci Transl Med. 2025 Jan 29; 17(783):eadp5173. PMID: 39879322.

Published on 1/1/2025

Berical AC, Kiyokawa H, Beermann ML, Wallman D, Cherfane G, Dunphy V, Pan J, Tilston-Lunel A, Varelas X, Horani A, Brody SL, Kotton DN, Hawkins FJ. Airway Disease Modeling with Gene-Edited Human Basal Cell Transplantation. Am J Respir Crit Care Med. 2025 Jan; 211(1):131-134. PMID: 39514838.

Published on 7/23/2024

Koenitzer JR, Gupta DK, Twan WK, Xu H, Hadas N, Hawkins FJ, Beermann ML, Penny GM, Wamsley NT, Berical A, Major MB, Dutcher SK, Brody SL, Horani A. Transcriptional analysis of primary ciliary dyskinesia airway cells reveals a dedicated cilia glutathione pathway. JCI Insight. 2024 Jul 23; 9(17). PMID: 39042459.

Published on 3/21/2024

Brody SL, Pan J, Huang T, Xu J, Xu H, Koenitizer J, Brennan SK, Nanjundappa R, Saba TG, Berical A, Hawkins FJ, Wang X, Zhang R, Mahjoub MR, Horani A, Dutcher SK. Loss of an extensive ciliary connectome induces proteostasis and cell fate switching in a severe motile ciliopathy. bioRxiv. 2024 Mar 21. PMID: 38562900.

Published on 8/24/2023

Ma L, Thapa BR, Le Suer JA, Tilston-Lünel A, Herriges MJ, Berical A, Beermann ML, Wang F, Bawa PS, Kohn A, Ysasi AB, Kiyokawa H, Matte TM, Randell SH, Varelas X, Hawkins FJ, Kotton DN. Airway stem cell reconstitution by the transplantation of primary or pluripotent stem cell-derived basal cells. Cell Stem Cell. 2023 Sep 07; 30(9):1199-1216.e7. PMID: 37625411.

Published on 7/29/2022

Berical A, Lee RE, Lu J, Beermann ML, Le Suer JA, Mithal A, Thomas D, Ranallo N, Peasley M, Stuffer A, Bukis K, Seymour R, Harrington J, Coote K, Valley H, Hurley K, McNally P, Mostoslavsky G, Mahoney J, Randell SH, Hawkins FJ. A multimodal iPSC platform for cystic fibrosis drug testing. Nat Commun. 2022 Jul 29; 13(1):4270. PMID: 35906215.

Published on 6/14/2022

Berical A, Beermann ML, Suzuki S, LeSuer J, Matte T, Davis B, Kotton D, Hawkins F. Generation of Airway Epithelial Cell Air-Liquid Interface Cultures from Human Pluripotent Stem Cells. J Vis Exp. 2022 Jun 14; (184). PMID: 35781291.