Alice K. Jacobs MD

Professor, Cardiovascular Medicine

88 E. Newton St | (617) 638-8707
Alice Jacobs

Cardiovascular Medicine


Whitaker Cardiovascular Institute

Evans Center for Interdisciplinary Biomedical Research


Alice K. Jacobs, MD, FACC, FAHA, MSCAI is a Professor of Medicine at Chobanian and Avedisian School of Medicine and served as the Director of the Cardiac Catheterization Laboratories and Interventional Cardiology for 20 years until 2011. She is currently Vice Chair for Clinical Affairs in the Department of Medicine at Boston University Medical Center and maintains an active clinical practice. Dr. Jacobs has led the American Heart Association’s Mission: Lifeline, a community-based, national initiative to develop systems of care for ST-segment elevation myocardial infarction (STEMI) patients and to increase the number of patients with timely access to primary percutaneous coronary intervention. Mission: Lifeline has now expanded to include Out-of-Hospital Cardiac Arrest and Stroke systems of care. Dr. Jacobs served as president of the American Heart Association in 2004-05 and as president of the Association of University Cardiologists in 2011. She is a past chair of the ACC/AHA Task Force on Practice Guidelines. During her tenure, the guidelines process and methodology evolved to include formal systematic evidence reviews, inclusion of patient representatives and lay members on guideline committees, incorporation of an Evidence Grading Tool, and further enhancements to the Class of Recommendation/Level of Evidence schema. Dr. Jacobs is a prior member of CMS MEDCAC and the IOM Committee on Social Security Cardiovascular Disability. Currently, she is the immediate past-chair of the American Board of Internal Medicine Interventional Cardiology Self-Assessment Test Committee, a member of NHLBI Cardiothoracic Surgical Network Protocol Review Committee and a member of the New York State Cardiac Advisory Committee. Her major research interest is in coronary revascularization strategies and sex-based difference in ischemic heart disease.

Expertise includes: Interventional Cardiology; Coronary revascularization; Sex-based differences in cardiovascular disease.


Medicine, MD, Saint Louis University, 1975

Biology, BA, State University of New York at Buffalo, 1971


Published on 5/22/2022

Hannan EL, Zhong Y, Ling FSK, LeMay M, Jacobs AK, King SB, Berger PB, Venditti FJ, Walford G, Tamis-Holland J. Relation of Operator Volume and Access Site to Short-Term Mortality in Radial Versus Femoral Access for Primary Percutaneous Coronary Intervention. Am J Cardiol. 2022 Aug 01; 176:30-36. PMID: 35613952.

Published on 5/11/2022

Hannan EL, Zhong Y, Reddy P, Jacobs AK, Ling FSK, King Iii SB, Berger PB, Venditti FJ, Walford G, Tamis-Holland J. Percutaneous Coronary Intervention With and Without Intravascular Ultrasound for Patients With Complex Lesions: Utilization, Mortality, and Target Vessel Revascularization. Circ Cardiovasc Interv. 2022 Jun; 15(6):e011687. PMID: 35543139.

Published on 3/22/2022

Ibrahim M, Fattouh M, Jacobs A. Management of Recurrent Pregnancy-Related Pericarditis. Case Rep Cardiol. 2022; 2022:5791307. PMID: 35360184.

Published on 3/15/2022

Huang Z, Rockhold FW, Jones WS, Hernandez AF, McCall D, DeMets DL, Hochman JS, Gersh BJ, Campos H, Jacobs AK, Yancy CW. The challenges of data safety monitoring for a pragmatic study: Lessons from the ADAPTABLE study. Contemp Clin Trials. 2022 Apr; 115:106732. PMID: 35301133.

Published on 10/13/2021

Jacobs AK, Ali MJ, Best PJ, Bieniarz MC, Bufalino VJ, French WJ, Henry TD, Hollowell L, Jauch EC, Kurz MC, Levy M, Patel P, Spier T, Stone RH, Tataris KL, Thomas RJ, Zègre-Hemsey JK. Systems of Care for ST-Segment-Elevation Myocardial Infarction: A Policy Statement From the American Heart Association. Circulation. 2021 11 16; 144(20):e310-e327. PMID: 34641735.

Published on 10/2/2021

Hannan EL, Wu Y, Cozzens K, Friedrich M, Walford G, Ling FSK, Venditti FJ, Jacobs AK, Tamis-Holland J, Berger PB, King SB. The Association of Socioeconomic Factors With Percutaneous Coronary Intervention Outcomes. Can J Cardiol. 2022 01; 38(1):13-22. PMID: 34610383.

Published on 3/28/2021

Hannan EL, Wu YF, Cozzens K, Tamis-Holland J, Ling FSK, Jacobs AK, Venditti FJ, Berger PB, Walford G, King Iii SB. Hybrid coronary revascularization vs. percutaneous coronary interventions for multivessel coronary artery disease. J Geriatr Cardiol. 2021 Mar 28; 18(3):159-167. PMID: 33907545.

Published on 12/8/2020

Hannan EL, Wu Y, Cozzens K, Friedrich M, Tamis-Holland J, Jacobs AK, Ling FSK, King SB, Venditti FJ, Walford G, Berger PB, Kirtane AJ, Kamran M. Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction Before and During COVID in New York. Am J Cardiol. 2021 03 01; 142:25-34. PMID: 33301770.

Published on 11/7/2020

Shahandeh N, Dai X, Jaski B, Dave R, Jacobs A, Denktas A, Levine G, Markovic D, Smith SC, Press MC. Mortality differences among patients with in-hospital ST-elevation myocardial infarction. Clin Cardiol. 2020 Dec; 43(12):1555-1561. PMID: 33159461.

Published on 7/1/2020

Mendirichaga R, Jacobs AK. Sex Differences in Ischemic Heart Disease-the Paradox Persists. JAMA Cardiol. 2020 07 01; 5(7):754-756. PMID: 32227138.

View full list of 411 publications.