Discovery of the Month: Dec 2018

“Retinoic Acid Signaling is Essential for Airway Smooth Muscle Homeostasis”

Felicia Chen, Fengzhi Shao, Anne Hinds, Sean Yao, Sumati Ram-Mohan, Timothy A. Norman, Ramaswamy Krishnan, and Alan Fine

Team led by Dr. Felicia Chen of the BU Pulmonary Center demonstrates that “Retinoic Acid signaling maintains airway smooth muscle homeostasis by preventing excessive activation of the TGF-β pathway. We conclude that tonic RA signaling is critical for postnatal airway health.”

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Presented by Dr. Chen at Grand Rounds, December 14, 2018

This is the first installment in the Dept of Medicine series, Discovery of the Month. Recent projects are recognized and featured during a special monthly grand rounds for significant findings and publications.

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