Richard Goldstein, a GSI Member, has been awarded a Hartwell Foundation Grant

BU Today: For decades, Richard Goldstein has been trying to unlock a genetic puzzle that holds the secret to a more effective vaccine for a pneumonia strain that kills more than a million children a year worldwide. For his work, the BU School of Medicine professor of pediatrics was recently awarded a three-year, $300,000 grant […]

GSI faculty member, Sam Thiagalingam, along with GPGG alumni, Panos Papageorgis, discover pathway responsible for epigenetic memory during breast cancer progression.

GSI faculty member, Sam Thiagalingam and GPGG alumni, Panos Papageorgis, from Boston University School of Medicine (BUSM) have determined how the TGFβ-Smad signaling pathway, is responsible for the “epigenetic memory” that maintains unique patterns of regulatory DNA hypermethylation, causing silencing of critical genes that facilitate breast cancer progression. The findings, which appear online in Cancer […]

GSI faculty participating in a panel discussion at the Boston premiere of I Remember Better When I Paint, an Alzheimer’s disease documentary on the impact of art on patients

GSI faculty member, Robert Green, MD, MPH, BUSM, professor of neurology, genetics and epidemiology participated in a panel discussion following the Boston premiere of  “I Remember Better When I Paint,” an Alzheimer’s disease documentary on January 12th. Click here for more information. http://www.bu.edu/phpbin/news/releases/display.php?id=1994

Mutant CTRC gene has a new way to trigger pancreatitis

GSI faculty member Miklos Sahin-Toth and colleague (Department of Molecular & Cell Biology, GSDM) have demonstrated that misfolding of mutant digestive enzymes also kills acinar cells —those that make and give out digestive enzymes. Click here for details.  Szmola R, Sahin-Toth M. Pancreatitis-associated chymotrypsinogen C (CTRC) mutant elicits endoplasmic reticulum stress in pancreatic acinar cells. […]

BUSM Researchers discover gene therapy to help prevent progression of emphysema

Researchers from Boston University School of Medicine (BUSM) have discovered a new gene therapy that may prevent the progression of emphysema. The study, which appears on-line in the Journal of Clinical Investigation, describes a method to express therapeutic genes in lung tissue for a lifetime after only a single treatment. Click here for details. Wilson […]

Genome Science Institute Announces Research Symposium Award Winners

The Genome Science Institute held its inaugural Research Symposium, an interdisciplinary research symposium that explores genetic and genomic science, in the Boston Medical Campus’ Hiebert Lounge on October 8, 2009. There were 63 abstracts submitted from students, post-doctoral fellows, and faculty from Institutions throughout the Boston area. Prizes were awarded in undergraduate, graduate and postdoctoral […]