BUSM Researchers discover gene therapy to help prevent progression of emphysema
Researchers from Boston University School of Medicine (BUSM) have discovered a new gene therapy that may prevent the progression of emphysema. The study, which appears on-line in the Journal of Clinical Investigation, describes a method to express therapeutic genes in lung tissue for a lifetime after only a single treatment. Click here for details. Wilson AA, Murphy GJ, Hamakawa H, Kwok LW, Srinivasan S, Hovav AH, Mulligan RC, Amar S, Suki B, Kotton DN. Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages. J ClinInvest. 2010 Jan;120(1):379-89. doi: 10.1172/JCI36666. Epub 2009 Dec 21. PubMed PMID: 20038801; PubMed Central PMCID: PMC2798672.