BU Spatial Biology Core

The Boston University Spatial Biology Core (SBC) is an in-house core facility providing access to and full-service data acquisition using:

  • 10x Genomics Visium CytAssist for spatial transcriptomics assays.
  • Standard BioTools Imaging Mass Cytometry Systems using metal-tagged antibodies or probes to detect 40+ markers (protein/RNA) within tissue samples at subcellular resolution.

In addition to these technologies, we also offer consultations to help users with preparing spatial assays, executing studies, and processing and analyzing data.

Services and Instrument Use Rates

Service Rates

Service Category Service Service Description Unit Internal* Rates External Academic Rates External+ Non-Academic Rates
Imaging Ab Conjugation/Validation (marker) Work up for utilization of antibodies in proteomic and transcriptomic workflows Per marker $139.00 $227.00 $247.00
Imaging mIF (per sample) Staining & imaging for transcriptomic workflows or validation for proteomic workflows Per sample $61.00 $100,00 $109.00
Imaging H&E (per sample) Staining & imaging for transcriptomic and proteomic workflows Per sample $11.00 $18.00 $20.00
Proteomics Ab Panel staining (per sample) Staining for proteomic workflows Per sample $289.00 $473.00 $514.00
Transcriptomics RNA QC (per sample) RNA isolation & QC for transcriptomic workflows Per sample $37.00 $60.00 $66.00
Training/Consulting Consultation/Analysis Service Hands-on training, consultation and/or analysis with a staff member Per hour $56.00 $92.00 $100.00

Instrument Use Rates

Service Category Instruments Instrument Description User Internal* Rates External Academic Rates External+ Non-Academic Rates
Proteomics Standard BioTools Image Mass Cytometer Imaging Mass Cytometry – 40+ Protein /RNA in situ imaging Assisted $166 per hour $271 per hour $295 per hour
Unassisted $133 per hour $216 per hour $235 per hour
Transcriptomics 10X Visium CytAssist Visium Whole Transcriptome Spatial Transcriptomics (Standard, HD, 3′ Assays) Assisted $589 per run $963 per run $1048 per run
Unassisted $195 per run $319 per run $347 per run

* Internal Rates: (Principal Investigators within Boston University)
+ External Rates: (Principal Investigators outside Boston University)

Preparing for Using the Spatial Biology Core

Workflow

Please submit a consultation request. Following a consultation session, BU users should log in to the iLab system (pending- SBC will reach out to schedule) to schedule equipment time or services.

Hours

  • The Core is open 24/7 for trained users working independently.
  • Training is available weekdays from 9 a.m. to 5 p.m. by appointment (please request several days in advance).
  • Each lab can book an instrument for a maximum of 12 hours per day.

Acknowledgments

We appreciate acknowledgment of the BU Spatial Biology Core in publications that include data acquired using Core equipment or assistance from Core personnel.

Letters of Support

We are happy to provide letters of support for grants. Please email us at spatial@bu.edu. If given ample time, we can also review imaging sections and provide preliminary data.

Contact

Sarah Mazzilli
Core Director
Phone: (617) 358-7269
Email: mazzilli@bu.edu

Location

Evans Building (E)
72 E. Concord Street, E641
Boston, MA 02118

View BU Medical Campus MAPS

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