Xueping Fan, MD, PhD

Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Expertise includes: Protein biochemistry; Signaling pathway study; Cell biology; Molecular genetics; Molecular nephrology; Neuroscience; and Pharmacology.

Publications

  • Published 2/25/2025

    Kumar S, Fan X, Pattam H, Yan K, Liaw EJ, Ji J, Zaltz E, Song P, Jiang Y, Nishizaki Y, Higashi Y, Cai CL, Lu W. ZEB2 signaling is essential for ureteral smooth muscle cell differentiation and maintenance. bioRxiv. 2025 Feb 25. PMID: 40060690.

    Read at: PubMed

  • Published 1/16/2025

    Hayashi N, Kumar S, Trivin-Avillach C, Fan X, Stoddard SV, Akai R, Fujimoto K, Iwawaki T, Yokoyama H, Furuichi K, Beck LH. Characterization of FAM114A1: a novel podocyte cytoskeleton-associated protein upregulated in glomerular injury. Am J Physiol Renal Physiol. 2025 Feb 01; 328(2):F289-F299. PMID: 39819080.

    Read at: PubMed

  • Published 3/24/2020

    Pisarek-Horowitz A, Fan X, Kumar S, Rasouly HM, Sharma R, Chen H, Coser K, Bluette CT, Hirenallur-Shanthappa D, Anderson SR, Yang H, Beck LH, Bonegio RG, Henderson JM, Berasi SP, Salant DJ, Lu W. Loss of Roundabout Guidance Receptor 2 (Robo2) in Podocytes Protects Adult Mice from Glomerular Injury by Maintaining Podocyte Foot Process Structure. Am J Pathol. 2020 04; 190(4):799-816. PMID: 32220420.

    Read at: PubMed

  • Published 11/17/2016

    Fan X, Yang H, Kumar S, Tumelty KE, Pisarek-Horowitz A, Rasouly HM, Sharma R, Chan S, Tyminski E, Shamashkin M, Belghasem M, Henderson JM, Coyle AJ, Salant DJ, Berasi SP, Lu W. SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion. JCI Insight. 2016 11 17; 1(19):e86934. PMID: 27882344.

    Read at: PubMed

  • Published 7/12/2012

    Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W. Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Rep. 2012 Jul 26; 2(1):52-61. PMID: 22840396.

    Read at: PubMed

Education

  • Zhejiang University, MD
  • McGill University, PhD
  • McGill University, MSc