William Edward Boden, MD

Professor, Medicine

William Boden
150 South Huntington Avenue


I am ABIM board-certified in both Internal Medicine and the subspecialty of Cardiovascular Disease. Since 1979, I have held university appointments at Brown University, Wayne State University, Tufts New England Medical Center, Boston University, the University of Connecticut, State University of New York in Buffalo, and Albany Medical College. For the past 27 consecutive years, I have held leadership roles as either a Chief of cardiology or Chief of Medicine at both federal VA facilities and in the academic private sector, all of which have had strong affiliations with their respective academic health centers. In 2016, I re-joined the VA Boston MAVERIC Center as the Scientific Director, Clinical Trials Network, for the VA New England Healthcare System, and as the Research Lead Physician, for VISN 1.

I have extensive prior experience in clinical trials and comparative effectiveness research, and have served in a leadership capacity in several important national and international clinical trials, including as Study Chair for VA CSP-funded VANQWISH and COURAGE Trials, as Study Co-Chair of the NIH-funded AIM-HIGH Trial, and as a national co-PI for the NIH-funded ISCHEMIA Trial. My principal research interests include studies in stable ischemic heart disease, post-MI secondary prevention, acute coronary syndromes, and preventive cardiology.

Other Positions

  • Lecturer in Medicine, Harvard Medical School
  • Physician Research Lead & Scientific Director, Clinical Trials Network, MAVERIC Center, VA Boston Healthcare System


  • State University of New York at Brockport, MD
  • Le Moyne College, BS


  • Published on 9/21/2023

    Weintraub WS, Boden WE. Can we measurably improve the prediction of recurrent coronary artery disease events? Eur Heart J. 2023 Sep 21; 44(36):3466-3468. PMID: 37738645.

    Read at: PubMed
  • Published on 9/19/2023

    Barili F, Anselmi A, Boden WE, Sousa Uva M, Parolari A. Concerns Regarding the Report of 3-Year Outcomes of the Evolut Low Risk Trial. J Am Coll Cardiol. 2023 Sep 19; 82(12):e101. PMID: 37704317.

    Read at: PubMed
  • Published on 7/25/2023

    Mavromatis K, Jones PG, Ali ZA, Stone GW, Rhodes GM, Bangalore S, O'Brien S, Genereux P, Horst J, Dressler O, Goodman S, Alexander K, Mathew A, Chen J, Bhargava B, Uxa A, Boden WE, Mark DB, Reynolds HR, Maron DJ, Hochman JS, Spertus JA. Complete Revascularization and Angina-Related Health Status in the ISCHEMIA Trial. J Am Coll Cardiol. 2023 Jul 25; 82(4):295-313. PMID: 37468185.

    Read at: PubMed
  • Published on 7/17/2023

    Stone GW, Ali ZA, O'Brien SM, Rhodes G, Genereux P, Bangalore S, Mavromatis K, Horst J, Dressler O, Poh KK, Nath RK, Moorthy N, Witkowski A, Dwivedi SK, Bockeria O, Chen J, Smanio PEP, Picard MH, Chaitman BR, Berman DS, Shaw LJ, Boden WE, White HD, Fremes SE, Rosenberg Y, Reynolds HR, Spertus JA, Hochman JS, Maron DJ. Impact of Complete Revascularization in the ISCHEMIA Trial. J Am Coll Cardiol. 2023 Sep 19; 82(12):1175-1188. PMID: 37462593.

    Read at: PubMed
  • Published on 7/3/2023

    Aggarwal R, Chiu N, Libby P, Boden WE, Bhatt DL. Low-Density Lipoprotein Cholesterol Levels in Adults With Coronary Artery Disease in the US, January 2015 to March 2020. JAMA. 2023 Jul 03; 330(1):80-82. PMID: 37395777.

    Read at: PubMed
  • Published on 6/16/2023

    Lincoff AM, Bhasin S, Flevaris P, Mitchell LM, Basaria S, Boden WE, Cunningham GR, Granger CB, Khera M, Thompson IM, Wang Q, Wolski K, Davey D, Kalahasti V, Khan N, Miller MG, Snabes MC, Chan A, Dubcenco E, Li X, Yi T, Huang B, Pencina KM, Travison TG, Nissen SE. Cardiovascular Safety of Testosterone-Replacement Therapy. N Engl J Med. 2023 Jul 13; 389(2):107-117. PMID: 37326322.

    Read at: PubMed
  • Published on 5/14/2023

    Boden WE, Kaski JC, Berry C. Reprising Heberden's description of angina pectoris after 250 years. Eur Heart J. 2023 May 14; 44(19):1684-1686. PMID: 36515090.

    Read at: PubMed
  • Published on 5/2/2023

    Nguyen DD, Spertus JA, Alexander KP, Newman JD, Dodson JA, Jones PG, Stevens SR, O'Brien SM, Gamma R, Perna GP, Garg P, Vitola JV, Chow BJW, Vertes A, White HD, Smanio PEP, Senior R, Held C, Li J, Boden WE, Mark DB, Reynolds HR, Bangalore S, Chan PS, Stone GW, Arnold SV, Maron DJ, Hochman JS. Health Status and Clinical Outcomes in Older Adults With Chronic Coronary Disease: The ISCHEMIA Trial. J Am Coll Cardiol. 2023 May 02; 81(17):1697-1709. PMID: 37100486.

    Read at: PubMed
  • Published on 4/2/2023

    Ostrominski JW, Boden WE. Defining the optimal approach to revascularization in chronic coronary syndrome patients with diabetes and multivessel disease: Is our equipoise evidence-based? Int J Cardiol Heart Vasc. 2023 Jun; 46:101200. PMID: 37255859.

    Read at: PubMed
  • Published on 3/9/2023

    Liga R, Colli A, Taggart DP, Boden WE, De Caterina R. Myocardial Revascularization in Patients With Ischemic Cardiomyopathy: For Whom and How. J Am Heart Assoc. 2023 Mar 21; 12(6):e026943. PMID: 36892041.

    Read at: PubMed

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