Sushrut S. Waikar, MD
Norman G. Levinsky Professor, Medicine
Biography
Sushrut S. Waikar, MD, MPH received a BA in English and Neuroscience at Amherst College, his MD at Yale, and an MPH at Harvard. He is the Norman G. Levinsky Professor of Medicine at Chobanian and Avedisian School of Medicine and Chief of Nephrology at Boston Medical Center. Dr. Waikar’s research interests and active projects include epidemiologic, translational, and interventional studies to address novel and clinically important questions in nephrology. Current areas of investigation include optimal diagnostic testing in acute kidney injury and chronic kidney disease; biomarkers of kidney pathology and kidney fibrosis; the identification of relevant targets for interventional trials in kidney disease; and randomized controlled trials. He is a Principal Investigator of several NIH grants including the Kidney Precision Medicine Project (U01 DK133092), Multi-omics and Chronic Kidney Disease: Correlation with Histology (R01 DK108803), Discovery Science Collaborative for CKDu (U01 DK130060), NAD Augmentation to Treat Diabetic Kidney Disease: A Randomized Controlled Trial (U01AG076789) andThe Boston University Kidney and Medical Engineering Program (BU-KIDMEP, R25 DK128858).
Other Positions
- Section Chief, Nephrology, Medicine, Boston University Chobanian & Avedisian School of Medicine
Education
- Yale University, MD
- Harvard School of Public Health, MPH
- Amherst College, BA
Publications
- Published on 10/1/2023
Buckley L, Palsson R, Waikar SS. Linking Kidney Vessel Scarring to Cardiovascular Risk-Reply. JAMA Cardiol. 2023 Oct 01; 8(10):1000. PMID: 37672259.
Read at: PubMed - Published on 9/20/2023
Zhu K, Mukherjee K, Wei C, Hayek SS, Collins A, Gu C, Corapi K, Altintas MM, Wang Y, Waikar SS, Bianco AC, Koch A, Tacke F, Reiser J, Sever S. The D2D3 form of uPAR acts as an immunotoxin and may cause diabetes and kidney disease. Sci Transl Med. 2023 Sep 20; 15(714):eabq6492. PMID: 37729431.
Read at: PubMed - Published on 8/24/2023
Sharma K, Zhang G, Hansen J, Bjornstad P, Lee HJ, Menon R, Hejazi L, Liu JJ, Franzone A, Looker HC, Choi BY, Fernandez R, Venkatachalam MA, Kugathasan L, Sridhar VS, Natarajan L, Zhang J, Sharma VS, Kwan B, Waikar SS, Himmelfarb J, Tuttle KR, Kestenbaum B, Fuhrer T, Feldman H, de Boer IH, Tucci FC, Sedor J, Heerspink HL, Schaub J, Otto EA, Hodgin JB, Kretzler M, Anderton CR, Alexandrov T, Cherney D, Lim SC, Nelson RG, Gelfond J, Iyengar R. Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients. J Clin Invest. 2023 Aug 24. PMID: 37616058.
Read at: PubMed - Published on 8/3/2023
Ferkowicz MJ, Verma A, Barwinska D, Ferreira RM, Henderson JM, Kirkpatrick M, Silva PS, Steenkamp DW, Phillips CL, Waikar SS, Sutton TA. Molecular Signatures of Glomerular Neovascularization in a Patient with Diabetic Kidney Disease. Clin J Am Soc Nephrol. 2023 Aug 03. PMID: 37533147.
Read at: PubMed - Published on 8/3/2023
Vasquez-Rios G, Katz R, Levitan EB, Cushman M, Parikh CR, Kimmel PL, Bonventre JV, Waikar SS, Schrauben SJ, Greenberg JH, Sarnak MJ, Ix JH, Shlipak MG, Gutierrez OM. Urinary Biomarkers of Kidney Tubule Health and Mortality in Persons with CKD and Diabetes Mellitus. Kidney360. 2023 Sep 01; 4(9):e1257-e1264. PMID: 37533144.
Read at: PubMed - Published on 8/1/2023
Rizzolo K, Gonzalez Jauregui R, Barrientos I, Teakell J, Camacho C, Chonchol M, Waikar SS, Cervantes L. Barriers and Facilitators to Home Dialysis Among Latinx Patients with Kidney Disease. JAMA Netw Open. 2023 Aug 01; 6(8):e2328944. PMID: 37581885.
Read at: PubMed - Published on 7/19/2023
Lake BB, Menon R, Winfree S, Hu Q, Ferreira RM, Kalhor K, Barwinska D, Otto EA, Ferkowicz M, Diep D, Plongthongkum N, Knoten A, Urata S, Mariani LH, Naik AS, Eddy S, Zhang B, Wu Y, Salamon D, Williams JC, Wang X, Balderrama KS, Hoover PJ, Murray E, Marshall JL, Noel T, Vijayan A, Hartman A, Chen F, Waikar SS, Rosas SE, Wilson FP, Palevsky PM, Kiryluk K, Sedor JR, Toto RD, Parikh CR, Kim EH, Satija R, Greka A, Macosko EZ, Kharchenko PV, Gaut JP, Hodgin JB, Eadon MT, Dagher PC, El-Achkar TM, Zhang K, Kretzler M, Jain S. An atlas of healthy and injured cell states and niches in the human kidney. Nature. 2023 Jul; 619(7970):585-594. PMID: 37468583.
Read at: PubMed - Published on 6/14/2023
Menon R, Otto EA, Barisoni L, Ferreira RM, Limonte CP, Godfrey B, Eichinger F, Nair V, Naik AS, Subramanian L, D'Agati V, Henderson JM, Herlitz L, Kiryluk K, Moledina DG, Moeckel GW, Palevsky PM, Parikh CR, Randhawa P, Rosas SE, Rosenberg AZ, Stillman I, Toto R, Torrealba J, Vazquez MA, Waikar S, Alpers CE, Nelson RG, Eadon MT, Kretzler M, Hodgin JB. Defining the molecular correlate of arteriolar hyalinosis in kidney disease progression by integration of single cell transcriptomic analysis and pathology scoring. medRxiv. 2023 Jun 14. PMID: 37398386.
Read at: PubMed - Published on 6/12/2023
Jiang K, Greenberg JH, Abraham A, Xu Y, Schelling JR, Feldman HI, Schrauben SJ, Waikar SS, Shlipak MG, Wettersten N, Coca SG, Vasan RS, Gutierrez OM, Ix JH, Warady BA, Kimmel PL, Bonventre JV, Parikh CR, Mitsnefes MM, Denburg MR, Furth S. Associations of Biomarkers of Kidney Tubule Health, Injury, and Inflammation with Left Ventricular Hypertrophy in Children with CKD. Kidney360. 2023 Aug 01; 4(8):1039-1047. PMID: 37303083.
Read at: PubMed - Published on 6/4/2023
Sharma K, Zhang G, Hansen J, Bjornstad P, Lee HJ, Menon R, Hejazi L, Liu JJ, Franzone A, Looker HC, Choi BY, Fernandez R, Venkatachalam MA, Kugathasan L, Sridhar VS, Natarajan L, Zhang J, Sharma V, Kwan B, Waikar S, Himmelfarb J, Tuttle K, Kestenbaum B, Fuhrer T, Feldman H, de Boer IH, Tucci FC, Sedor J, Heerspink HL, Schaub J, Otto E, Hodgin JB, Kretzler M, Anderton C, Alexandrov T, Cherney D, Lim SC, Nelson RG, Gelfond J, Iyengar R. Role of endogenous adenine in kidney failure and mortality with diabetes. medRxiv. 2023 Jun 04. PMID: 37398187.
Read at: PubMed
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