Sophie E. Claudel, MD

Clinical Instructor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Sophie Claudel is a nephrology fellow and early-career investigator at Boston Medical Center and the Boston University Chobanian & Avedisian School of Medicine, where she studies the intersection of chronic kidney disease, obesity, and cardiovascular disease. She earned her MD from the Wake Forest University School of Medicine and completed a clinical research fellowship at the National Institutes of Health. Dr. Claudel came to Boston Medical Center for internal medicine residency and chief residency through the NIH R38-funded Promoting Research in Medical Residency (PRIMER) pathway, and remained for nephrology fellowship in the clinical-research track.

Dr. Claudel’s current work investigates cardiovascular-kidney-metabolic syndrome using open databases (NHANES, UK Biobank), the Kidney Precision Medicine Project, and established longitudinal cohorts (CRIC, FHS, MESA, CARDIA). Her long-term goal is to integrate clinical epidemiology with physiologic studies in human participants to uncover shared disease mechanisms and, ultimately, inform strategies for treatment and prevention.

Dr. Claudel is also a member of the CURE Consortium, a multinational research group investigating the causes of chronic kidney disease of unknown etiology (CKDu) in Central America and India. The Renal Science Core, specifically, focuses on measuring novel kidney biomarkers and assessing longitudinal kidney function trajectories.

Publications

  • Published 9/23/2026

    Verma A, Schmidt IM, Claudel SE, Waikar SS. Prediction Utility of Urinary Albumin-Creatinine vs Protein-Creatinine Ratios in Chronic Kidney Disease. JAMA. 2026 Sep 23. PMID: 42776523.

    Read at: PubMed

  • Published 9/17/2026

    Bakhshi B, Lin H, Sultana N, Healey E, Queen H, Gao G, Claudel SE, Minetti ET, Mitchell GF, Murabito JM, Lloyd-Jones DM, Cheney MC, Steenkamp DW, Nayor M, Xanthakis V, Walker ME, Spartano NL. Beyond Traditional Glycemic Measures: CGM Glycemic Profiles Reveal Associations With Cardiometabolic Risk in Individuals Without Diabetes. Diabetes Care. 2026 Sep 17. PMID: 42752803.

    Read at: PubMed

  • Published 7/9/2026

    Claudel SE, Verma A. Trends and Prevalence of Chronic Kidney Disease in the United States. N Engl J Med. 2026 Jul 09; 395(2):201-203. PMID: 42418783.

    Read at: PubMed

  • Published 7/3/2026

    Claudel SE, Verma A. Trends in Prevalence of Diabetes, Pre-Diabetes, and Cardiometabolic Risk Factor Control Among U.S. Adults, 2013-2023. Diabetes Obes Metab. 2026 Sep; 28(9):8581-8594. PMID: 42396720.

    Read at: PubMed

  • Published 6/4/2026

    Rosan SH, Verma A, Claudel SE, Srivastava A, Palsson R, Stillman IE, Henderson J, Waikar SS, Schmidt IM. Associations of serum uric acid levels with podocyte injury and kidney histopathologic lesions. J Nephrol. 2026 Jun 04; 39(1):215-217. PMID: 41921046.

    Read at: PubMed

Other Positions

  • Resident Physician, Nephrology
    Boston Medical Center