Rachel Epstein, MD, MScE

Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Rachel L. Epstein, MD, MScE, is a clinician-scientist working to utilize large data sets and decision modelling to inform policy and program design to improve care for individuals with Hepatitis C, HIV, and substance use, with a particular focus on pregnant women and youth.

Dr. Epstein completed combined residency training in internal medicine-pediatrics at Brown University, and worked in primary care through the Providence Community Health Centers and the Hasbro Adolescent Center before fellowship. She completed a combined adult and pediatric infectious diseases fellowship at Boston Medical Center and a T32 post-doctoral research fellowship through the Boston University Clinical HIV/AIDS Research Training Program (BU-CHART). She is an Assistant Professor in the BUSM Department of Medicine, Section of Infectious Diseases, and Department of Pediatrics, Section of Infectious Diseases and sees adult and pediatric patients living with or at risk for Hepatitis C virus, HIV, and other infectious diseases. She also serves as the Med-Peds faculty specific advisor lead for BUSM students.

Dr. Epstein's current and recent work includes projects analyzing the effects of Medicaid HCV treatment restrictions on care cascade outcome achievement, HIV prevention and medication adherence, and comparing the cost-effectiveness of HCV and OUD screening, evaluation, and treatment interventions in women of reproductive age, children, and the general population. She currently or previously works/worked with data through OCHIN, TriNetX, the BMC Datawarehouse and COVID-19 Repository, Marketscan, and the Massachusetts Public Health Datawarehouse.

Publications

  • Published 2/11/2026

    Campbell JI, Brooks MB, Dankovchik J, Giebultowicz S, Falkenstein A, Angier H, Horsburgh CR, Tschampl CA, Haberer JE, Bressler J, Epstein RL, Jenkins HE, Jacobson K. Uncovering household tuberculosis infection testing and care patterns using a novel bioinformatics linkage strategy. Clin Infect Dis. 2026 Feb 11. PMID: 41668263.

    Read at: PubMed

  • Published 11/19/2025

    van Santen DK, Chalouni M, Berenguer J, Jarrin I, Miro JM, Klein MB, Young J, Torgersen J, Rentsch CT, Gill MJ, Epstein RL, Nunes D, Surial B, Rauch A, Touloumi G, Papadopoulos A, Wittkop L, Gilbert C, Leleux O, van der Valk M, Boyd A, Monforte AD, Puoti M, Zangerle R, Gisinger M, Logan RW, Rein S, Hernán MA, Lodi S. Risk of hepatocellular carcinoma after direct-acting antiviral treatment for hepatitis C virus infection in people with HIV. Clin Infect Dis. 2025 Nov 19. PMID: 41253696.

    Read at: PubMed

  • Published 5/1/2025

    Curtis MR, Munroe S, Biondi BE, Ciaranello AL, Linas BP, Epstein RL. Disparities in Linkage to Care Among Children With Hepatitis C Virus in the United States. Pediatrics. 2025 May 01; 155(5). PMID: 40246302.

    Read at: PubMed

  • Published 4/15/2025

    Singh RP, Biondi B, Gordon SH, Linas BP, Epstein RL. Hepatitis C Virus Screening in Pregnant and Nonpregnant Women After Universal Screening Guidelines. JAMA. 2025 Apr 15; 333(15):1356-1358. PMID: 39992633.

    Read at: PubMed

  • Published 2/24/2025

    Epstein RL, Munroe S, Taylor LE, Duryea PR, Buzzee B, Pramanick T, Feld JJ, Baptiste D, Carroll M, Castera L, Sterling RK, Thomas A, Chan PA, Linas BP. Clinical- and Cost-Effectiveness of Liver Disease Staging in Hepatitis C Virus Infection: A Microsimulation Study. Clin Infect Dis. 2025 Feb 24; 80(2):300-313. PMID: 39535186.

    Read at: PubMed

View All 32 Publications:   View Full Profile in BUMC

Other Positions

  • Assistant Professor, Pediatrics
    Boston University Chobanian & Avedisian School of Medicine

Websites

Education

  • Thomas Jefferson University, MD
  • Boston University School of Public Health, MSc
  • Wesleyan University, MA
  • Wesleyan University, BA

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