Phillip J. Stone, PhD
Emeritus Professor, Biochemistry & Cell Biology
Biography
Dr. Stone is Emeritus Professor of Biochemistry at Chobanian and Avedisian School of Medicine. He began in 1971 as a postdoc for Marrott Sinex, the Chair of Biochemistry at that time with a second postdoc in Carl Franzblau’s lab beginning in 1973, followed by a Young Investigator Award, NHLBI. Besides his current responsibilities as Assistant Dean of Admissions for the Medical School, he is also the department representative on the Institutional Animal Care and Use Committee. Dr. Stone also teaches in MD512/OH751 (Dental Biochemistry) the myoglobin and hemoglobin section and supervise student presented cases on sickle cell disease in dental medicine. He holds two patents: Measuring Connective Tissue Breakdown Products in Body Fluids. U.S. Patent No. 5,217,903 issued 6/8/93 and Measuring Tissue Breakdown Products in Body Fluids. U.S. Patent No. 5,354,662 issued 10/11/94.
Other Positions
- Assistant Dean, Admissions, Boston University Chobanian & Avedisian School of Medicine
- Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Education
- Temple University, PhD
- University of Pennsylvania, MA
- Swarthmore College, BS
Publications
- Published on 3/3/2017
Seidl SE, Pessolano LG, Bishop CA, Best M, Rich CB, Stone PJ, Schreiber BM. Toll-like receptor 2 activation and serum amyloid A regulate smooth muscle cell extracellular matrix. PLoS One. 2017; 12(3):e0171711. PMID: 28257481.
Read at: PubMed - Published on 9/20/2012
Pessolano LG, Sullivan CP, Seidl SE, Rich CB, Liscum L, Stone PJ, Sipe JD, Schreiber BM. Trafficking of endogenous smooth muscle cell cholesterol: a role for serum amyloid A and interleukin-1ß. Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):2741-50. PMID: 22995521.
Read at: PubMed - Published on 12/15/2011
Isenberg BC, Backman DE, Kinahan ME, Jesudason R, Suki B, Stone PJ, Davis EC, Wong JY. Micropatterned cell sheets with defined cell and extracellular matrix orientation exhibit anisotropic mechanical properties. J Biomech. 2012 Mar 15; 45(5):756-61. PMID: 22177672.
Read at: PubMed - Published on 6/1/2010
Guarnieri F, Spencer JL, Lucey EC, Nugent MA, Stone PJ. A human surfactant peptide-elastase inhibitor construct as a treatment for emphysema. Proc Natl Acad Sci U S A. 2010 Jun 8; 107(23):10661-6. PMID: 20534582.
Read at: PubMed - Published on 10/29/2009
Zhao Y, Chen L, Gao S, Toselli P, Stone P, Li W. The critical role of the cellular thiol homeostasis in cadmium perturbation of the lung extracellular matrix. Toxicology. 2010 Jan 12; 267(1-3):60-9. PMID: 19879314.
Read at: PubMed - Published on 1/14/2009
Ritter MC, Jesudason R, Majumdar A, Stamenovic D, Buczek-Thomas JA, Stone PJ, Nugent MA, Suki B. A zipper network model of the failure mechanics of extracellular matrices. Proc Natl Acad Sci U S A. 2009 Jan 27; 106(4):1081-6. PMID: 19144920.
Read at: PubMed - Published on 1/1/2009
Seidl S, Rich CB, Sullivan CP, Stone PJ, Schreiber BM. Arteriosclerosis Thrombosis and Vascular Biology. Serum Amyloid A Downregulates Elastin and Upregulates Matrix Metalloproteinase-9 Gene Expression in Smooth Muscle Cells. 2009.
- Published on 1/1/2009
Jesudason RE, Allen PG, Parameswaran H, Suki B, Stone PJ. American Thoracic Society 2009 International Conference. Interaction between Elastase Activity and Mechanical Forces in Lung Tissue Strips. San Diego. 2009.
Read at: Custom - Published on 11/9/2007
Black LD, Allen PG, Morris SM, Stone PJ, Suki B. Mechanical and failure properties of extracellular matrix sheets as a function of structural protein composition. Biophys J. 2008 Mar 1; 94(5):1916-29. PMID: 17993498.
Read at: PubMed - Published on 6/27/2007
Gao S, Zhao Y, Kong L, Toselli P, Chou IN, Stone P, Li W. Cloning and characterization of the rat lysyl oxidase gene promoter: identification of core promoter elements and functional nuclear factor I-binding sites. J Biol Chem. 2007 Aug 31; 282(35):25322-37. PMID: 17597074.
Read at: PubMed
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