John V. Wylie, MD, FACC

Adjunct Associate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Areas of research interest include atrial fibrillation ablation and integration of imaging techniques into electrophysiology procedures. He has previously performed extensive collaboration between
electrophysiology and cardiac magnetic resonance imaging. This involved a number of ongoing research projects in cardiac imaging for electrophysiology procedures.

From 2005-2007, he managed a large database of patients undergoing atrial fibrillation ablation designed to evaluate outcomes of this procedure, and subsequently served as the Principal Investigator and supervised fellows in management of this database from 2007-2008.

He has served as a site Principal Investigator in a number of multicenter trials, including the Attain-Success trial, from 2010-2012, the ACUITY trial, from January, 2016 –
present, and the GLORIA-AF trial, from February, 2015 – present. His primary research interests are in ablation and diagnostic techniques in clinical electrophysiology, specifically atrial flutter and atrial fibrillation.

Publications

  • Published 7/14/2025

    Dina A, Demchuk K, Koulouridis I, Dutta R, Jetty V, Bhattacharya A, Zorin D, Astsaturov A, Hagenah K, Elgabry I, Ebersol K, Goldman A, Natan S, Wylie JV, Orlov MV. Procedural Outcomes and Conduction System Capture Pattern Maintenance With the Tendril STS™ 2088TC Lead and CPS Locator™ 3D Delivery System: A Comparative Analysis With Lumenless Lead System. J Cardiovasc Electrophysiol. 2025 Sep; 36(9):2296-2303. PMID: 40654184.

    Read at: PubMed

  • Published 12/5/2024

    Nadeem B, Sedrakyan S, Fatima A, Baig MMA, Ahmed A, Sherwani MRK, Wylie J. Outcomes of concurrent and delayed leadless pacemaker implantation following extraction of infected cardiovascular implantable electronic device. J Interv Card Electrophysiol. 2025 Oct; 68(7):1523-1529. PMID: 39633137.

    Read at: PubMed

  • Published 4/11/2024

    Dutta R, Ryan JG, Hurley S, Wylie J. A targeted educational intervention increases oral anticoagulation rates in high-risk atrial fibrillation patients. Heart Rhythm O2. 2024 May; 5(5):294-300. PMID: 38840762.

    Read at: PubMed

  • Published 11/17/2023

    Wylie JV, Demchuk K, Koulouridis I, Jetty V, Dutta R, Bhattacharya A, Zorin D, Astsaturov A, Goldman A, Natan S, Orlov MV. Right-sided approach for left bundle branch area pacing is feasible and successful. Heart Rhythm. 2024 Mar; 21(3):352-354. PMID: 37979899.

    Read at: PubMed

  • Published 10/20/2022

    Dutta R, Hurley S, Atkins D, Weinstein J, Wylie J. High rates of oral anticoagulation in atrial fibrillation patients observed in a large multi-specialty health system in the Northeast. J Interv Card Electrophysiol. 2023 Aug; 66(5):1119-1124. PMID: 36264386.

    Read at: PubMed

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Websites

Education

  • Harvard Medical School, MD
  • Harvard College, AB

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