John H. Connor, PhD

Associate Professor, Virology, Immunology & Microbiology

John Connor
617.358.9155
620 Albany Street

Biography

My laboratory studies the virus-host interaction. We take a variety of approaches from genetic to systems biology to biochemistry and molecular biology. We are studying how viruses take over the cellular protein synthesis apparatus, how cells effectively fight virus infection, and how the host responds to infection with viruses that cause hemorrhagic fever.

Other Positions

  • Faculty, National Emerging Infectious Disease Lab, Boston University
  • Member, Genome Science Institute, Boston University
  • Member, Bioinformatics Graduate Program, Boston University
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Education

  • Duke University, PhD
  • Swarthmore College, BA

Publications

  • Published on 6/8/2023

    Woolsey C, Strampe J, Fenton KA, Agans KN, Martinez J, Borisevich V, Dobias NS, Deer DJ, Geisbert JB, Cross RW, Connor JH, Geisbert TW. A recombinant vesicular stomatitis virus-based vaccine provides postexposure protection against Bundibugyo ebolavirus infection. J Infect Dis. 2023 Jun 08. PMID: 37290053.

    Read at: PubMed
  • Published on 5/12/2023

    Tseng AE, Carossino M, Gertje HP, O'Connell AK, Gummuluru S, Kolachalama VB, Balasuriya UBR, Connor JH, Bennett RS, Liu DX, Hensley LE, Crossland NA. Hepatic proinflammatory myeloid phenotypes are a hallmark of Ebola virus Kikwit pathogenesis in rhesus monkeys. Vet Pathol. 2023 Jul; 60(4):473-487. PMID: 37170900.

    Read at: PubMed
  • Published on 5/5/2023

    Carmola LR, Turcinovic J, Draper G, Webner D, Putukian M, Silvers-Granelli H, Bombin A, Connor BA, Angelo KM, Kozarsky P, Libman M, Huits R, Hamer DH, Fairley JK, Connor JH, Piantadosi A, Bourque DL. Genomic Epidemiology of a Severe Acute Respiratory Syndrome Coronavirus 2 Outbreak in a US Major League Soccer Club: Was It Travel Related? Open Forum Infect Dis. 2023 Jun; 10(6):ofad235. PMID: 37323423.

    Read at: PubMed
  • Published on 4/10/2023

    Chen DY, Turcinovic J, Feng S, Kenney DJ, Chin CV, Choudhary MC, Conway HL, Semaan M, Close BJ, Tavares AH, Seitz S, Khan N, Kapell S, Crossland NA, Li JZ, Douam F, Baker SC, Connor JH, Saeed M. Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus. iScience. 2023 May 19; 26(5):106634. PMID: 37095858.

    Read at: PubMed
  • Published on 2/8/2023

    Bouton TC, Atarere J, Turcinovic J, Seitz S, Sher-Jan C, Gilbert M, White L, Zhou Z, Hossain MM, Overbeck V, Doucette-Stamm L, Platt J, Landsberg HE, Hamer DH, Klapperich C, Jacobson KR, Connor JH. Viral Dynamics of Omicron and Delta Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants With Implications for Timing of Release from Isolation: A Longitudinal Cohort Study. Clin Infect Dis. 2023 Feb 08; 76(3):e227-e233. PMID: 35737948.

    Read at: PubMed
  • Published on 2/8/2023

    Petros BA, Turcinovic J, Welch NL, White LF, Kolaczyk ED, Bauer MR, Cleary M, Dobbins ST, Doucette-Stamm L, Gore M, Nair P, Nguyen TG, Rose S, Taylor BP, Tsang D, Wendlandt E, Hope M, Platt JT, Jacobson KR, Bouton T, Yune S, Auclair JR, Landaverde L, Klapperich CM, Hamer DH, Hanage WP, MacInnis BL, Sabeti PC, Connor JH, Springer M. Early Introduction and Rise of the Omicron Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variant in Highly Vaccinated University Populations. Clin Infect Dis. 2023 Feb 08; 76(3):e400-e408. PMID: 35616119.

    Read at: PubMed
  • Published on 1/11/2023

    Chen DY, Chin CV, Kenney D, Tavares AH, Khan N, Conway HL, Liu G, Choudhary MC, Gertje HP, O'Connell AK, Adams S, Kotton DN, Herrmann A, Ensser A, Connor JH, Bosmann M, Li JZ, Gack MU, Baker SC, Kirchdoerfer RN, Kataria Y, Crossland NA, Douam F, Saeed M. Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation. Nature. 2023 Mar; 615(7950):143-150. PMID: 36630998.

    Read at: PubMed
  • Published on 1/10/2023

    Chen DY, Kenney D, Chin CV, Tavares AH, Khan N, Conway HL, Liu G, Choudhary MC, Gertje HP, O'Connell AK, Kotton DN, Herrmann A, Ensser A, Connor JH, Bosmann M, Li JZ, Gack MU, Baker SC, Kirchdoerfer RN, Kataria Y, Crossland NA, Douam F, Saeed M. Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron. bioRxiv. 2023 Jan 10. PMID: 36263066.

    Read at: PubMed
  • Published on 1/6/2023

    Seymour E, Ünlü MS, Connor JH. A high-throughput single-particle imaging platform for antibody characterization and a novel competition assay for therapeutic antibodies. Sci Rep. 2023 Jan 06; 13(1):306. PMID: 36609657.

    Read at: PubMed
  • Published on 12/23/2022

    Boytz R, Seitz S, Gaudiano E, Patten JJ, Keiser PT, Connor JH, Sharpe AH, Davey RA. Inactivation of Ebola Virus and SARS-CoV-2 in Cell Culture Supernatants and Cell Pellets by Gamma Irradiation. Viruses. 2022 Dec 23; 15(1). PMID: 36680083.

    Read at: PubMed

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