Jayandra J. Himali, PhD

Adjunct Associate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Jayandra Jung Himali, PhD, serves as an adjunct Associate Professor of Neurology and Biostatistics at Boston University Schools of Medicine and of Public Health, and a Center Faculty Member of the Framingham Heart Study (FHS). He has been engaged in collaborative public health research and teaching for over a decade. As a senior Biostatistician at the Neurology core of FHS, his research efforts are focused on the interrelated areas of: (1) the epidemiology of dementia and Alzheimer’s disease (AD) and relating traditional and novel biomarkers to the risk of dementia and AD; (2) the epidemiology of stroke and vascular cognitive impairment; (3) understanding vascular contributions to cognitive impairment and dementia including AD; and (4) investigating the role of modifiable lifestyle factors: sleep, diet and physical activity on the incidence of dementia, cognitive decline and MRI-defined brain aging. His research is also focused on outcome assessment in Epilepsy, Parkinson’s disease, and neuropathology. He has received the Nepal Bidhya Bhusan Class ‘A’ Medal from the government of Nepal for highest academic achievement in doctoral studies.

Publications

  • Published 5/1/2026

    Young VM, Wiedner C, Baril AA, Pase MP, Ruiz A, Salardini A, Frei CR, Kautz T, Bernal R, Yiallourou S, Cribb L, Beiser A, Teixeira AL, Himali JJ, Seshadri S. Non-linear associations between sleep duration and plasma p-tau181 in the Framingham Heart Study. Alzheimers Dement. 2026 May; 22(5):e71499. PMID: 42156936.

    Read at: PubMed

  • Published 4/2/2026

    Giorgio K, Stephen JJ, Mansolf M, Peterson EA, Gross AL, Briceño EM, Levine DA, Helmer C, Debette S, Soumaré A, Ikram MA, Wolters FJ, Seshadri S, Satizabal CL, Himali JJ, Launer LJ, Li D, Mbangdadji D, Lloyd-Jones DM, Sorond FA, Zhao L, Lopez OL, Judd SE, Hughes TM, Guðnason V, Aiello AE, Fohner A, Singh-Manoux A, Sabayan B, Pankow JS, de Vries PS, Yaffe K, Beiser A, Dehghan A, Zmora R, Scholtens D, Lutsey PL, Allen NB, MacLehose R, Sedaghat S. Risk factors for early-onset and late-onset dementia: a prospective cohort study. Lancet Healthy Longev. 2026 Mar; 7(3):100831. PMID: 41936382.

    Read at: PubMed

  • Published 3/19/2026

    Palatsides EL, Himali D, Cribb L, Peloso GM, Ryan J, Yang Q, Decarli CS, Beiser AS, Seshadri S, Cavuoto MG, Yiallourou S, Baril AA, Himali JJ, Pase MP. Association of an Aquaporin-4 Haplotype With Cognition, Brain Volume, and Dementia Risk in Community-Dwelling Individuals Without Dementia. Neurology. 2026 Apr 14; 106(7):e214773. PMID: 41855452.

    Read at: PubMed

  • Published 3/9/2026

    Liou JJ, Santini T, Li J, Gireud-Goss M, Kautz TF, Parker-Garza J, Guerrero JC, Patel V, Adeyemi OF, de Erausquin GA, Garbarino VR, Habes M, Himali JJ, Karmonik C, Snitz BE, Mettenburg JM, Wu M, Aizenstein HJ, Marsland AL, Gianaros PJ, Bowtell R, Mougin O, Gowland PA, Katshu MZ, Vahidy FS, Girard TD, Jacobs HIL, Hosseini AA, Seshadri S, Ibrahim TS. Examining neuroimaging biomarkers, plasma biomarkers and cognitive functions in patients with recovered COVID-19 infection: a multicentre study using 7T MRI. Brain Commun. 2026; 8(2):fcag045. PMID: 41809434.

    Read at: PubMed

  • Published 3/5/2026

    Honnorat N, Wang D, Ho NH, Martinez D, Brandigampala SR, Heckbert SR, Bahrami M, Himali JJ, DeCarli C, Beiser A, Hughes TM, Seshadri S, Habes M. Derivation of machine learning brain aging biomarkers for a set of forty thousand functional connectomes. Brain Res Bull. 2026 Apr; 237:111815. PMID: 41794271.

    Read at: PubMed

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Other Positions

  • Investigator
    Framingham Heart Study

Websites

Education

  • Boston University School of Public Health, PhD
  • Tribhuvan University, MSc
  • Tribhuvan University, BSc

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