Ivana Delalle, MD, PhD

Professor, Pathology & Laboratory Medicine

Ivana Delalle


Dr. Delalle is a Professor of Pathology and Laboratory Medicine at the Warren Alpert School of Medicine at Brown University. She is a Director of Neuropathology Service at Lifespan Academic Medical Center. Dr. Delalle attended the Zagreb University School of Medicine, Zagreb, Croatia, where she received her MD in 1988 and, in 1992, her PhD in the Developmental Neuroanatomy Laboratory headed by Professor Ivica Kostovic, a pioneer in the understanding of transient layers in the developing human cortex. Dr. Delalle subsequently joined Developmental Neurobiology Laboratory headed by Professor Verne Caviness at Massachusetts General Hospital (MGH) in Boston where she elucidated the expression of cell cycle regulators in relation to the cortical development. After completing her Research Fellowship in Neurology at Harvard Medical School in 1997, Dr. Delalle pursued further postgraduate training as a resident in Anatomic Pathology and Neuropathology in the Department of Pathology at MGH. She became board certified by the American Board of Pathology in Anatomic Pathology and Neuropathology in 2001. Before joining Lifespan Academic Medical Center and Brown University, Dr. Delalle worked in the teaching hospitals of Harvard Medical School and Chobanian and Avedisian School of Medicine as a scientist investigating neurodegenerative and neuropsychiatric diseases, as a neuropathologist with expertise in neurooncology in the clinical arena, and as a teacher and mentor committed to the education of medical students, residents, and neuropathology fellows.

Other Positions

  • Associate Professor, Neurology, Boston University Chobanian & Avedisian School of Medicine
  • Professor, Pathology & Laboratory Medicine, Brown University
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University


  • University of Zagreb, MD
  • University of Zagreb, PhD


  • Published on 3/25/2024

    Kaurani L, Islam MR, Heilbronner U, Krüger DM, Zhou J, Methi A, Strauss J, Pradhan R, Schröder S, Burkhardt S, Schuetz AL, Pena T, Erlebach L, Bühler A, Budde M, Senner F, Kohshour MO, Schulte EC, Schmauß M, Reininghaus EZ, Juckel G, Kronenberg-Versteeg D, Delalle I, Odoardi F, Flügel A, Schulze TG, Falkai P, Sananbenesi F, Fischer A. Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice. EMBO J. 2024 Apr; 43(8):1420-1444. PMID: 38528182.

    Read at: PubMed
  • Published on 2/26/2024

    Alexander A, Alvarez VE, Huber BR, Alosco ML, Mez J, Tripodis Y, Nicks R, Katz DI, Dwyer B, Daneshvar DH, Martin B, Palmisano J, Goldstein LE, Crary JF, Nowinski C, Cantu RC, Kowall NW, Stern RA, Delalle I, McKee AC, Stein TD. Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE. Acta Neuropathol. 2024 Feb 26; 147(1):45. PMID: 38407651.

    Read at: PubMed
  • Published on 2/22/2023

    Castro-Hernández R, Berulava T, Metelova M, Epple R, Peña Centeno T, Richter J, Kaurani L, Pradhan R, Sakib MS, Burkhardt S, Ninov M, Bohnsack KE, Bohnsack MT, Delalle I, Fischer A. Conserved reduction of m6A RNA modifications during aging and neurodegeneration is linked to changes in synaptic transcripts. Proc Natl Acad Sci U S A. 2023 Feb 28; 120(9):e2204933120. PMID: 36812208.

    Read at: PubMed
  • Published on 11/16/2022

    Tubre T, Hacking S, Alexander A, Brickman A, Delalle I, Elinzano H, Donahue JE. Prostate-Specific Membrane Antigen Expression in Meningioma: A Promising Theranostic Target. J Neuropathol Exp Neurol. 2022 Nov 16; 81(12):1008-1017. PMID: 36179256.

    Read at: PubMed
  • Published on 10/27/2022

    Oraki Kohshour M, Papiol S, Delalle I, Rossner MJ, Schulze TG. Extracellular vesicle approach to major psychiatric disorders. Eur Arch Psychiatry Clin Neurosci. 2023 Sep; 273(6):1279-1293. PMID: 36302978.

    Read at: PubMed
  • Published on 7/29/2022

    Schulze TG, Delalle I. Engineered extracellular vesicles and their promising therapeutic potential in neuropsychiatric disorders. Eur Neuropsychopharmacol. 2022 Oct; 63:14-16. PMID: 35914375.

    Read at: PubMed
  • Published on 4/1/2021

    Delalle I. MicroRNAs as Candidates for Bipolar Disorder Biomarkers. Psychiatr Danub. 2021 Spring-Summer; 33(Suppl 4):451-455. PMID: 34718264.

    Read at: PubMed
  • Published on 2/1/2021

    Kanach C, Blusztajn JK, Fischer A, Delalle I. MicroRNAs as Candidate Biomarkers for Alzheimer's Disease. Noncoding RNA. 2021 Feb 01; 7(1). PMID: 33535543.

    Read at: PubMed
  • Published on 7/28/2020

    Anderson KE, Bellio TA, Aniskovich E, Adams SL, Blusztajn JK, Delalle I. The Expression of Activin Receptor-Like Kinase 1 (ACVRL1/ALK1) in Hippocampal Arterioles Declines During Progression of Alzheimer's Disease. Cereb Cortex Commun. 2020; 1(1):tgaa031. PMID: 32974611.

    Read at: PubMed
  • Published on 10/7/2019

    Jain G, Stuendl A, Rao P, Berulava T, Pena Centeno T, Kaurani L, Burkhardt S, Delalle I, Kornhuber J, Hüll M, Maier W, Peters O, Esselmann H, Schulte C, Deuschle C, Synofzik M, Wiltfang J, Mollenhauer B, Maetzler W, Schneider A, Fischer A. A combined miRNA-piRNA signature to detect Alzheimer's disease. Transl Psychiatry. 2019 10 07; 9(1):250. PMID: 31591382.

    Read at: PubMed

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