Farzad Mortazavi, PhD

Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Mortazavi received his B.A. in psychology from the University of South Florida, M.S at Central Michigan University, and his Ph.D. at Northeastern University in Experimental Psychology and Behavioral Neuroscience. As a postdoctoral fellow, he was a Michel J. Fox Foundation Fellow in the Department of Neurology at UCLA where his studies focused on molecular and neuroanatomical changes in neurodegenerative disorders. He is currently an Assistant Professor in the Department of Anatomy and Neurobiology and his primary research is focused on 3D farzad_2reconstruction of white-matter pathways and cortical columns using Confocal Microscopy, 2-photon Microscopy and statistical physics for analysis of these types of big data. He also collaborates with Drs. Moss, Rosene, Killiany, and Moore in the Laboratory for Cognitive Neurobiology. The laboratory focuses on the effects of normal aging on structure and function of cerebral cortex and cortical ischemia in a non-human primate model.

Dr. Mortazavi teaches the statistics course in the department of Anatomy and Neurobiology and has been training students in immunohistochemistry, cell counts and image analysis among other techniques. He is actively involved in the Forensic Anthropology program where he teaches Experimental Design and Analysis for Forensic Anthropologists.

Publications

  • Published 9/30/2024

    Cheng CH, Guan Y, Chiplunkar VP, Mortazavi F, Medalla ML, Sullivan K, O'Callaghan JP, Koo BB, Kelly KA, Michalovicz LT. Nerve agent exposure and physiological stress alter brain microstructure and immune profiles after inflammatory challenge in a long-term rat model of Gulf War Illness. Brain Behav Immun Health. 2024 Dec; 42:100878. PMID: 39430882.

    Read at: PubMed

  • Published 5/16/2024

    Vitantonio AT, Dimovasili C, Mortazavi F, Vaughan KL, Mattison JA, Rosene DL. Long-term calorie restriction reduces oxidative DNA damage to oligodendroglia and promotes homeostatic microglia in the aging monkey brain. Neurobiol Aging. 2024 Sep; 141:1-13. PMID: 38788462.

    Read at: PubMed

  • Published 11/22/2023

    DeVries SA, Conner B, Dimovasili C, Moore TL, Medalla M, Mortazavi F, Rosene DL. Immune proteins C1q and CD47 may contribute to aberrant microglia-mediated synapse loss in the aging monkey brain that is associated with cognitive impairment. Geroscience. 2024 Apr; 46(2):2503-2519. PMID: 37989825.

    Read at: PubMed

  • Published 12/22/2022

    Taylor EN, Huang N, Lin S, Mortazavi F, Wedeen VJ, Siamwala JH, Gilbert RJ, Hamilton JA. Lipid and smooth muscle architectural pathology in the rabbit atherosclerotic vessel wall using Q-space cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2022 Dec 22; 24(1):74. PMID: 36544161.

    Read at: PubMed

  • Published 8/5/2022

    Dimovasili C, Fair AE, Garza IR, Batterman KV, Mortazavi F, Moore TL, Rosene DL. Aging compromises oligodendrocyte precursor cell maturation and efficient remyelination in the monkey brain. Geroscience. 2023 Feb; 45(1):249-264. PMID: 35930094.

    Read at: PubMed

View All 36 Publications:   View Full Profile in BUMC

Other Positions

  • Graduate Faculty (Primary Mentor of Grad Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Websites

Education

  • Northeastern University, PhD
  • Central Michigan University, MS
  • University of South Florida, BA

View all profiles