Dr. Wolf’s research focuses on the use of multivariate data analytic techniques, such as confirmatory factor analysis, structural equation modeling, latent class analysis, and item response theory, to evaluate trauma, posttraumatic stress disorder (PTSD), and related comorbidity. She is currently studying the genetics of latent psychopathology using both twin and molecular genetic methodologies. In particular, her recent work has focused on the idea that PTSD is associated with accelerated cellular aging, as reflected in DNA methylation and as manifested in physical health and neurocognitive decline.
- VA Boston Healthcare System
- Boston University, PhD
- Boston University, MA
- Harvard University, ALB
- Published on 7/26/2023
Chatzinakos C, Pernia CD, Morrison FG, Iatrou A, McCullough KM, Schuler H, Snijders C, Bajaj T, DiPietro CP, Soliva Estruch M, Gassen NC, Anastasopoulos C, Bharadwaj RA, Bowlby BC, Hartmann J, Maihofer AX, Nievergelt CM, Ressler NM, Wolf EJ, Carlezon WA, Krystal JH, Kleinman JE, Girgenti MJ, Huber BR, Kellis M, Logue MW, Miller MW, Ressler KJ, Daskalakis NP. Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response. Am J Psychiatry. 2023 Jul 26; appiajp20220478. PMID: 37491937.
- Published on 7/7/2023
Wolf EJ, Higgins DM, Zhao X, Hawn SE, Sanborn V, Todd CA, Fein-Schaffer D, Houranieh A, Miller MW. MMPI-2-RF Profiles of Treatment-Seeking Veterans in a VA Pain Clinic and Associations with Markers of Physical Performance. J Clin Psychol Med Settings. 2023 Jul 07. PMID: 37418093.
- Published on 4/6/2023
Wolf EJ, Hawn SE, Sullivan DR, Miller MW, Sanborn V, Brown E, Neale Z, Fein-Schaffer D, Zhao X, Logue MW, Fortier CB, McGlinchey RE, Milberg WP. Neurobiological and genetic correlates of the dissociative subtype of posttraumatic stress disorder. J Psychopathol Clin Sci. 2023 May; 132(4):409-427. PMID: 37023279.
- Published on 2/15/2023
Hawn SE, Zhao X, Sullivan DR, Logue M, Fein-Schaffer D, Milberg W, McGlinchey R, Miller MW, Wolf EJ. Correction to: For whom the bell tolls: psychopathological and neurobiological correlates of a DNA methylation index of time-to-death. Transl Psychiatry. 2023 Feb 15; 13(1):56. PMID: 36792580.
- Published on 12/22/2022
Sherva R, Zhang R, Sahelijo N, Jun G, Anglin T, Chanfreau C, Cho K, Fonda JR, Gaziano JM, Harrington KM, Ho YL, Kremen WS, Litkowski E, Lynch J, Neale Z, Roussos P, Marra D, Mez J, Miller MW, Salat DH, Tsuang D, Wolf E, Zeng Q, Panizzon MS, Merritt VC, Farrer LA, Hauger RL, Logue MW. African ancestry GWAS of dementia in a large military cohort identifies significant risk loci. Mol Psychiatry. 2023 Mar; 28(3):1293-1302. PMID: 36543923.
- Published on 12/22/2022
Logue MW, Miller MW, Sherva R, Zhang R, Harrington KM, Fonda JR, Merritt VC, Panizzon MS, Hauger RL, Wolf EJ, Neale Z, Gaziano JM. Alzheimer's disease and related dementias among aging veterans: Examining gene-by-environment interactions with post-traumatic stress disorder and traumatic brain injury. Alzheimers Dement. 2023 Jun; 19(6):2549-2559. PMID: 36546606.
- Published on 10/25/2022
Zhao X, Logue MW, Hawn SE, Neale ZE, Zhou Z, Huber BR, Miller MW, Wolf EJ. PTSD, major depression, and advanced transcriptomic age in brain tissue. Depress Anxiety. 2022 Dec; 39(12):824-834. PMID: 36281744.
- Published on 9/24/2022
Hawn SE, Zhao X, Sullivan DR, Logue M, Fein-Schaffer D, Milberg W, McGlinchey R, Miller MW, Wolf EJ. For whom the bell tolls: psychopathological and neurobiological correlates of a DNA methylation index of time-to-death. Transl Psychiatry. 2022 Sep 24; 12(1):406. PMID: 36153327.
- Published on 6/6/2022
Hawn SE, Wolf EJ, Neale Z, Miller MW. Conceptualizing traumatic stress and the structure of posttraumatic psychopathology through the lenses of RDoC and HiTOP. Clin Psychol Rev. 2022 Jul; 95:102177. PMID: 35690042.
- Published on 3/21/2022
Hawn SE, Neale Z, Wolf EJ, Zhao X, Pierce M, Fein-Schaffer D, Milberg W, McGlinchey R, Logue M, Miller MW. Methylation of the AIM2 gene: An epigenetic mediator of PTSD-related inflammation and neuropathology plasma biomarkers. Depress Anxiety. 2022 Apr; 39(4):323-333. PMID: 35312143.
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