Erika J. Wolf, PhD
Professor, Psychiatry
Biography
Dr. Wolf’s research focuses on the use of multivariate data analytic techniques, such as confirmatory factor analysis, structural equation modeling, latent class analysis, and item response theory, to evaluate trauma, posttraumatic stress disorder (PTSD), and related comorbidity. She is currently studying the genetics of latent psychopathology using both twin and molecular genetic methodologies. In particular, her recent work has focused on the idea that PTSD is associated with accelerated cellular aging, as reflected in DNA methylation and as manifested in physical health and neurocognitive decline.
Other Positions
- VA Boston Healthcare System
Education
- Boston University, PhD
- Boston University, MA
- Harvard University, ALB
Publications
- Published on 4/1/2024
Maihofer AX, Ratanatharathorn A, Hemmings SMJ, Costenbader KH, Michopoulos V, Polimanti R, Rothbaum AO, Seedat S, Mikita EA, Smith AK, Salem RM, Shaffer RA, Wu T, Sebat J, Ressler KJ, Stein MB, Koenen KC, Wolf EJ, Sumner JA, Nievergelt CM. Effects of genetically predicted posttraumatic stress disorder on autoimmune phenotypes. Transl Psychiatry. 2024 Apr 01; 14(1):172. PMID: 38561342.
Read at: PubMed - Published on 3/2/2024
Miller MW, Wolf EJ, Zhao X, Logue MW, Hawn SE. An EWAS of dementia biomarkers and their associations with age, African ancestry, and PTSD. Clin Epigenetics. 2024 Mar 02; 16(1):38. PMID: 38431614.
Read at: PubMed - Published on 2/15/2024
Wani A, Katrinli S, Zhao X, Daskalakis N, Zannas A, Aiello A, Baker D, Boks M, Brick L, Chen CY, Dalvie S, Fortier C, Geuze E, Hayes J, Kessler R, King A, Koen N, Liberzon I, Lori A, Luykx J, Maihofer A, Milberg W, Miller M, Mufford M, Nugent N, Rauch S, Ressler K, Risbrough V, Rutten B, Stein D, Stein M, Ursano R, Verfaellie M, Ware E, Wildman D, Wolf E, Nievergelt C, Logue M, Smith A, Uddin M, Vermetten E, Vinkers C. Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts. Res Sq. 2024 Feb 15. PMID: 38410438.
Read at: PubMed - Published on 1/16/2024
Crowe ML, Hawn SE, Wolf EJ, Keane TM, Marx BP. Trauma exposure and transdiagnostic distress: Examining shared and posttraumatic stress disorder-specific associations. J Trauma Stress. 2024 Jan 16. PMID: 38229407.
Read at: PubMed - Published on 11/13/2023
Wolf EJ, Miller MW, Hawn SE, Zhao X, Wallander SE, McCormick B, Govan C, Rasmusson A, Stone A, Schichman SA, Logue MW. Longitudinal study of traumatic-stress related cellular and cognitive aging. Brain Behav Immun. 2024 Jan; 115:494-504. PMID: 37967663.
Read at: PubMed - Published on 9/21/2023
Hawn SE, Zhao X, Miller MW, Wallander S, Govan C, Stone A, Schichman SA, Logue MW, Wolf EJ. PTSD and Alcohol Use Disorders Predict the Pace of Cellular Aging. J Mood Anxiety Disord. 2023 Oct; 3. PMID: 37900051.
Read at: PubMed - Published on 9/2/2023
Nievergelt CM, Maihofer AX, Atkinson EG, Chen CY, Choi KW, Coleman JR, Daskalakis NP, Duncan LE, Polimanti R, Aaronson C, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, Austin SB, Avdibegoviç E, Babic D, Bacanu SA, Baker DG, Batzler A, Beckham JC, Belangero S, Benjet C, Bergner C, Bierer LM, Biernacka JM, Bierut LJ, Bisson JI, Boks MP, Bolger EA, Brandolino A, Breen G, Bressan RA, Bryant RA, Bustamante AC, Bybjerg-Grauholm J, Bækvad-Hansen M, Børglum AD, Børte S, Cahn L, Calabrese JR, Caldas-de-Almeida JM, Chatzinakos C, Cheema S, Clouston SAP, Colodro-Conde L, Coombes BJ, Cruz-Fuentes CS, Dale AM, Dalvie S, Davis LK, Deckert J, Delahanty DL, Dennis MF, deRoon-Cassini T, Desarnaud F, DiPietro CP, Disner SG, Docherty AR, Domschke K, Dyb G, Kulenovic AD, Edenberg HJ, Evans A, Fabbri C, Fani N, Farrer LA, Feder A, Feeny NC, Flory JD, Forbes D, Franz CE, Galea S, Garrett ME, Gelaye B, Gelernter J, Geuze E, Gillespie CF, Goci A, Goleva SB, Gordon SD, Grasser LR, Guindalini C, Haas M, Hagenaars S, Hauser MA, Heath AC, Hemmings SM, Hesselbrock V, Hickie IB, Hogan K, Hougaard DM, Huang H, Huckins LM, Hveem K, Jakovljevic M, Javanbakht A, Jenkins GD, Johnson J, Jones I, Jovanovic T, Karstoft KI, Kaufman ML, Kennedy JL, Kessler RC, Khan A, Kimbrel NA, King AP, Koen N, Kotov R, Kranzler HR, Krebs K, Kremen WS, Kuan PF, Lawford BR, Lebois LAM, Lehto K, Levey DF, Lewis C, Liberzon I, Linnstaedt SD, Logue MW, Lori A, Lu Y, Luft BJ, Lupton MK, Luykx JJ, Makotkine I, Maples-Keller JL, Marchese S, Marmar C, Martin NG, MartÍnez-Levy GA, McAloney K, McFarlane A, McLaughlin KA, McLean SA, Medland SE, Mehta D, Meyers J, Michopoulos V, Mikita EA, Milani L, Milberg W, Miller MW, Morey RA, Morris CP, Mors O, Mortensen PB, Mufford MS, Nelson EC, Nordentoft M, Norman SB, Nugent NR, O'Donnell M, Orcutt HK, Pan PM, Panizzon MS, Pathak GA, Peters ES, Peterson AL, Peverill M, Pietrzak RH, Polusny MA, Porjesz B, Powers A, Qin XJ, Ratanatharathorn A, Risbrough VB, Roberts AL, Rothbaum BO, Rothbaum AO, Roy-Byrne P, Ruggiero KJ, Rung A, Runz H, Rutten BPF, de Viteri SS, Salum GA, Sampson L, Sanchez SE, Santoro M, Seah C, Seedat S, Seng JS, Shabalin A, Sheerin CM, Silove D, Smith AK, Smoller JW, Sponheim SR, Stein DJ, Stensland S, Stevens JS, Sumner JA, Teicher MH, Thompson WK, Tiwari AK, Trapido E, Uddin M, Ursano RJ, Valdimarsdóttir U, van den Heuvel LL, Van Hooff M, van Rooij SJ, Vermetten E, Vinkers CH, Voisey J, Wang Z, Wang Y, Waszczuk M, Weber H, Wendt FR, Werge T, Williams MA, Williamson DE, Winsvold BS, Winternitz S, Wolf EJ, Wolf C, Xia Y, Xiong Y, Yehuda R, Young RM, Young KA, Zai CC, Zai GC, Zervas M, Zhao H, Zoellner LA, Zwart JA, Stein MB, Ressler KJ, Koenen KC. Discovery of 95 PTSD loci provides insight into genetic architecture and neurobiology of trauma and stress-related disorders. medRxiv. 2023 Sep 02. PMID: 37693460.
Read at: PubMed - Published on 7/26/2023
Chatzinakos C, Pernia CD, Morrison FG, Iatrou A, McCullough KM, Schuler H, Snijders C, Bajaj T, DiPietro CP, Soliva Estruch M, Gassen NC, Anastasopoulos C, Bharadwaj RA, Bowlby BC, Hartmann J, Maihofer AX, Nievergelt CM, Ressler NM, Wolf EJ, Carlezon WA, Krystal JH, Kleinman JE, Girgenti MJ, Huber BR, Kellis M, Logue MW, Miller MW, Ressler KJ, Daskalakis NP. Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response. Am J Psychiatry. 2023 Oct 01; 180(10):739-754. PMID: 37491937.
Read at: PubMed - Published on 7/7/2023
Wolf EJ, Higgins DM, Zhao X, Hawn SE, Sanborn V, Todd CA, Fein-Schaffer D, Houranieh A, Miller MW. MMPI-2-RF Profiles of Treatment-Seeking Veterans in a VA Pain Clinic and Associations with Markers of Physical Performance. J Clin Psychol Med Settings. 2024 Mar; 31(1):58-76. PMID: 37418093.
Read at: PubMed - Published on 4/6/2023
Wolf EJ, Hawn SE, Sullivan DR, Miller MW, Sanborn V, Brown E, Neale Z, Fein-Schaffer D, Zhao X, Logue MW, Fortier CB, McGlinchey RE, Milberg WP. Neurobiological and genetic correlates of the dissociative subtype of posttraumatic stress disorder. J Psychopathol Clin Sci. 2023 May; 132(4):409-427. PMID: 37023279.
Read at: PubMed
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