My reseach focuses on the use of multivariate data analytic techniques, such as confirmatory factor analysis, structural equation modeling, latent class analysis, and item response theory, to evaluate trauma, posttraumatic stress disorder (PTSD), and related comorbidity. I am currently studying the genetics of latent psychopathology using both twin and molecular genetic methodologies. In particular, my recent work has focused on the idea that PTSD is associated with accelerated cellular aging, as reflected in DNA methylation and as manifested in physical health and neurocognitive decline.
- VA Boston Healthcare System
- Boston University, PhD
- Boston University, MA
- Harvard University, ALB
- Published on 1/1/2018
Wolf EJ, Logue MW, Stoop TB, Schichman SA, Stone A, Sadeh N, Hayes JP, Miller MW. Accelerated DNA Methylation Age: Associations With Posttraumatic Stress Disorder and Mortality. Psychosom Med. 2018 Jan; 80(1):42-48. PMID: 29271864.
- Published on 12/28/2017
Wolf EJ, Miller MW, Sullivan DR, Amstadter AB, Mitchell KS, Goldberg J, Magruder KM. A classical twin study of PTSD symptoms and resilience: Evidence for a single spectrum of vulnerability to traumatic stress. Depress Anxiety. 2017 Dec 28. PMID: 29283198.
- Published on 10/9/2017
Miller MW, Lin AP, Wolf EJ, Miller DR. Oxidative Stress, Inflammation, and Neuroprogression in Chronic PTSD. Harv Rev Psychiatry. 2017 Oct 09. PMID: 29016379.
- Published on 9/20/2017
Logue MW, van Rooij SJH, Dennis EL, Davis SL, Hayes JP, Stevens JS, Densmore M, Haswell CC, Ipser J, Koch SBJ, Korgaonkar M, Lebois LAM, Peverill M, Baker JT, Boedhoe PSW, Frijling JL, Gruber SA, Harpaz-Rotem I, Jahanshad N, Koopowitz S, Levy I, Nawijn L, O'Connor L, Olff M, Salat DH, Sheridan MA, Spielberg JM, van Zuiden M, Winternitz SR, Wolff JD, Wolf EJ, Wang X, Wrocklage K, Abdallah CG, Bryant RA, Geuze E, Jovanovic T, Kaufman ML, King AP, Krystal JH, Lagopoulos J, Bennett M, Lanius R, Liberzon I, McGlinchey RE, McLaughlin KA, Milberg WP, Miller MW, Ressler KJ, Veltman DJ, Stein DJ, Thomaes K, Thompson PM, Morey RA. Smaller Hippocampal Volume in Posttraumatic Stress Disorder: A Multisite ENIGMA-PGC Study: Subcortical Volumetry Results From Posttraumatic Stress Disorder Consortia. Biol Psychiatry. 2018 Feb 01; 83(3):244-253. PMID: 29217296.
- Published on 9/1/2017
Miller MW, Maniates H, Wolf EJ, Logue MW, Schichman SA, Stone A, Milberg W, McGlinchey R. CRP polymorphisms and DNA methylation of the AIM2 gene influence associations between trauma exposure, PTSD, and C-reactive protein. Brain Behav Immun. 2018 Jan; 67:194-202. PMID: 28867284.
- Published on 8/29/2017
Wolf EJ, Morrison FG. Traumatic Stress and Accelerated Cellular Aging: From Epigenetics to Cardiometabolic Disease. Curr Psychiatry Rep. 2017 Aug 29; 19(10):75. PMID: 28852965.
- Published on 8/15/2017
Logue MW, Smith AK, Wolf EJ, Maniates H, Stone A, Schichman SA, McGlinchey RE, Milberg W, Miller MW. The correlation of methylation levels measured using Illumina 450K and EPIC BeadChips in blood samples. Epigenomics. 2017 Nov; 9(11):1363-1371. PMID: 28809127.
- Published on 7/28/2017
Hayes JP, Reagan A, Logue MW, Hayes SM, Sadeh N, Miller DR, Verfaellie M, Wolf EJ, McGlinchey RE, Milberg WP, Stone A, Schichman SA, Miller MW. BDNF genotype is associated with hippocampal volume in mild traumatic brain injury. Genes Brain Behav. 2017 Jul 28. PMID: 28755387.
- Published on 7/20/2017
Wolf EJ, Logue MW, Stoop TB, Schichman SA, Stone A, Sadeh N, Hayes JP, Miller MW. Accelerated DNA Methylation Age: Associations with PTSD and Mortality. Psychosom Med. 2017 Jul 20. PMID: 28731985.
- Published on 7/6/2017
Wisco BE, Marx BP, Miller MW, Wolf EJ, Krystal JH, Southwick SM, Pietrzak RH. A comparison of ICD-11 and DSM criteria for posttraumatic stress disorder in two national samples of U.S. military veterans. J Affect Disord. 2017 Dec 01; 223:17-19. PMID: 28715723.
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