Donald Lloyd-Jones, MD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Lloyd-Jones’ research interests include the study of the mechanisms and life course of cardiovascular health and healthy aging, and cardiovascular disease epidemiology, risk estimation and prevention. Other areas of interest include the use of novel biomarkers and imaging of subclinical atherosclerosis to improve prevention, and the epidemiology and outcomes of hypertension and dyslipidemia. His clinical and teaching interests lie in general cardiology, with a focus on prevention.

He also has been a national leader in public health and clinical approaches to promoting cardiovascular health and preventing cardiovascular diseases across the life course. He served as co-chair of the Risk Assessment Guidelines and a member of the Cholesterol Treatment Guidelines Panel for the 2013 ACC/AHA Guidelines for Cardiovascular Disease Risk Reduction; and was the lead member for risk assessment on the 2018 Cholesterol Guidelines Panel and the 2019 Primary Prevention Guidelines Panel. He has authored over 750 peer-reviewed scientific publications and has been a PI or co-investigator on more than 120 grants (the vast majority from NIH)

Publications

  • Published 8/7/2026

    Domanski MJ, Wu CO, Tian X, Shalhoub R, Miao R, Roney PC, Davis SN, Hasan AA, Reis JP, Bae S, Jacobs DR, Lloyd-Jones DM, Fuster V. Diabetes Mellitus, Cumulative Glucose Exposure, and Incident Cardiovascular Disease Risk. JACC Adv. 2026 Aug 07; 5(9):103087. PMID: 42567096.

    Read at: PubMed

  • Published 8/5/2026

    Khan SS, Sang Y, Huang X, Petito LC, Hong C, Pencina M, Ballew SH, Grams ME, Ndumele CE, Lloyd-Jones DM, Grobman WA, Coresh J. External Validation of the PREVENT Equations in a National Sample of US Adults. Circ Popul Health Outcomes. 2026 Aug 05; e012988. PMID: 42554063.

    Read at: PubMed

  • Published 8/1/2026

    Wang N, DiCorpo DA, Zhang Y, Kleinbrink E, Arnett DK, Barnard J, Blangero J, Bowden DW, Carson AP, Chen YI, Chung MK, Curran JE, Darbar D, Duggirala R, Ellinor PT, Fatkin D, Fornage M, Heard-Costa N, He J, Hou L, Kardia SLR, Kooperberg C, Loos RJF, McManus DD, Mitchell BD, Minster RL, North KE, Psaty BM, Raffield LM, Redline S, Rich SS, Roden D, Rotter JI, Shoemaker MB, Smith JD, Van Wagoner DR, Aguet F, Ardlie K, Bis JC, Brody JA, Cade BE, Clish CB, de Vries PS, Floyd JS, Freedman BI, Gabriel S, Gerzsten RE, Goodarzi MO, Gu C, Guo X, Gupta N, Heckbert SR, Hsu S, Hung YJ, Kalyani RR, Kelly TN, Kinney GL, Li C, Liu S, Liu Y, Lloyd-Jones DM, Manson JE, Mathias RA, Mercader JM, Morrison AC, Naseri T, Onengut S, Palmer ND, Peyser PA, Qi Q, Raghavan S, Reiner AP, Rooney MR, Sevilla-Gonzalez M, Sarnowski C, Smith JD, Smith JA, Spartano NL, Tahir U, Taylor KD, Tobias DK, Tracy RP, Viali S, Wang H, Wood AC, Yanek LR, Zhao W, Zheng Y, Dupuis J, Liu CT, Sladek R, Wessel J, Meigs JB, Manning AK. Colocalization of eQTLs With Type 2 Diabetes and Glycemic Traits Using Whole-Genome Sequences in Diverse Populations From the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program. Diabetes. 2026 Aug 01; 75(8):1477-1491. PMID: 42274313.

    Read at: PubMed

  • Published 7/31/2026

    Zhang Y, Schaefer EJ, Ikezaki H, Diffenderfer MR, Lloyd-Jones DM, Hoogeveen RC, Ballantyne CM, DeFilippis AP, Guan W, Tsai MY, Liu CT. Comprehensive Evaluation of Atherosclerotic Cardiovascular Disease Risk Predictors Across the Pooled Cohort Equations, Predicting Risk of Cardiovascular Disease Events, and an Expanded Model. J Am Heart Assoc. 2026 Aug 04; 15(15):e049726. PMID: 42535551.

    Read at: PubMed

  • Published 7/27/2026

    Lloyd-Jones DM. Cardiovascular-Kidney-Metabolic Syndrome: A Historic Perspective. Circulation. 2026 Jul 28; 154(4):416-419. PMID: 42507780.

    Read at: PubMed

Other Positions

  • Director of Framingham Center for Population and Prevention Science, Framingham Heart Study
    Boston University
  • Principal Investigator of the Framingham Heart Study, Framingham Heart Study
    Boston University
  • Chief of the section, Preventive Medicine
    Boston University

Education

  • Columbia University College of Physicians and Surgeons, MD
  • Harvard School of Public Health, MS
  • Swarthmore College, BA