Donald Lloyd-Jones, MD
Professor, Medicine
Biography
Dr. Lloyd-Jones’ research interests include the study of the mechanisms and life course of cardiovascular health and healthy aging, and cardiovascular disease epidemiology, risk estimation and prevention. Other areas of interest include the use of novel biomarkers and imaging of subclinical atherosclerosis to improve prevention, and the epidemiology and outcomes of hypertension and dyslipidemia. His clinical and teaching interests lie in general cardiology, with a focus on prevention.
He also has been a national leader in public health and clinical approaches to promoting cardiovascular health and preventing cardiovascular diseases across the life course. He served as co-chair of the Risk Assessment Guidelines and a member of the Cholesterol Treatment Guidelines Panel for the 2013 ACC/AHA Guidelines for Cardiovascular Disease Risk Reduction; and was the lead member for risk assessment on the 2018 Cholesterol Guidelines Panel and the 2019 Primary Prevention Guidelines Panel. He has authored over 750 peer-reviewed scientific publications and has been a PI or co-investigator on more than 120 grants (the vast majority from NIH)
Other Positions
- Director of Framingham Center for Population and Prevention Science, Framingham Heart Study, Boston University
- Principal Investigator of the Framingham Heart Study, Framingham Heart Study, Boston University
- Chief of the section, Preventive Medicine, Boston University
Websites
Education
- Columbia University College of Physicians and Surgeons, MD
- Harvard School of Public Health, MS
- Swarthmore College, BA
Publications
- Published on 4/2/2025
Freaney PM, Huang X, Petito LC, Grobman WA, Catov J, Hauspurg A, Bairey Merz CN, Bello N, Kim JK, Lane A, Haas DM, Levine LD, McNeil RB, Miller E, Saade G, Theilen L, Yee LM, Varagic J, Mercer B, Reddy U, Lloyd-Jones DM, Greenland P, Khan SS. Adverse Pregnancy Outcomes and N-Terminal Pro-Brain Natriuretic Peptide Levels 2 to 7 Years After Delivery: The nuMoM2b Heart Health Study. JAMA Cardiol. 2025 Apr 02. PMID: 40172904.
Read at: PubMed - Published on 3/31/2025
Krishnan V, Huang X, Perak AM, Coresh J, Ndumele CE, Greenland P, Lloyd-Jones DM, Khan SS. Discordance of 10- and 30-Year Predicted Risk for Cardiovascular Disease in US Adults. JAMA. 2025 Mar 31. PMID: 40163044.
Read at: PubMed - Published on 3/25/2025
Lee GN, Ying W, Ambale-Venkatesh B, Nwabuo CC, de Vasconcellos HD, Michos ED, Ouyang P, Ndumele C, Schreiner PJ, Reis JP, Lloyd-Jones DM, Lewis CE, Sidney S, Wu CO, Hoogeveen R, Lima JAC, Post WS, Vaidya D. Longitudinal changes in circulating cyclic guanosine monophosphate in women over the menopause transition compared to men: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Menopause. 2025 Mar 25. PMID: 40132085.
Read at: PubMed - Published on 3/11/2025
Lloyd-Jones DM, Khan S. Statins for Primary Prevention of Cardiovascular Disease-Reply. JAMA. 2025 Mar 11; 333(10):910. PMID: 39937489.
Read at: PubMed - Published on 3/7/2025
El-Sabawi B, Betti M, Lin P, Huang X, Kim N, Yaser Anwar M, Perry AS, Perera BLA, Gajjar P, Colangelo LA, Amancherla K, Sheng Q, Zhao S, Stolze L, Farber-Eger E, Landman JM, Miller PE, Liu GY, Das S, Wells QS, Terry JG, Lloyd-Jones D, Das S, Khan SS, North KE, Below J, Nayor M, Kalhan R, Carr JJ, Gamazon ER, Shah RV. Molecular architecture of human atherosclerosis revealed through integrative human genetics. medRxiv. 2025 Mar 07. PMID: 40093223.
Read at: PubMed - Published on 3/1/2025
Bhatt SP, Wu C, Sun Y, Balte PP, Schwartz JE, Divo MJ, Jaeger BC, Chaves PH, Couper D, Jacobs DR, Lloyd-Jones D, Kalhan R, Newman AB, O'Connor GT, Umans JG, White WB, Yende S, Oelsner EC. Low Lung Function Is Associated with High Population Attributable Fraction for Cardiovascular Mortality. Ann Am Thorac Soc. 2025 Mar; 22(3):359-366. PMID: 39447115.
Read at: PubMed - Published on 2/19/2025
Szeto MD, Ning H, Pedamallu H, Zheng Y, Schneper L, Joyce B, Kim K, Kershaw KN, Reges O, Hou L, Allen NB, Notterman DA, Lloyd-Jones DM. Mediation of Social Determinants and Hypertension by Epigenetic Age in CARDIA. Hypertension. 2025 Mar; 82(3):e22-e24. PMID: 39970248.
Read at: PubMed - Published on 2/14/2025
Iyer KR, Clarke SL, Guarischi-Sousa R, Gjoni K, Heath AS, Young EP, Stitziel NO, Laurie C, Broome JG, Khan AT, Lewis JP, Xu H, Montasser ME, Ashley KE, Hasbani NR, Boerwinkle E, Morrison AC, Chami N, Do R, Rocheleau G, Lloyd-Jones DM, Lemaitre RN, Bis JC, Floyd JS, Kinney GL, Bowden DW, Palmer ND, Benjamin EJ, Nayor M, Yanek LR, Kral BG, Becker LC, Kardia SLR, Smith JA, Bielak LF, Norwood AF, Min YI, Carson AP, Post WS, Rich SS, Herrington D, Guo X, Taylor KD, Manson JE, Franceschini N, Pollard KS, Mitchell BD, Loos RJF, Fornage M, Hou L, Psaty BM, Young KA, Regan EA, Freedman BI, Vasan RS, Levy D, Mathias RA, Peyser PA, Raffield LM, Kooperberg C, Reiner AP, Rotter JI, Jun G, de Vries PS, Assimes TL. Unveiling the Genetic Landscape of Coronary Artery Disease Through Common and Rare Structural Variants. J Am Heart Assoc. 2025 Feb 18; 14(4):e036499. PMID: 39950338.
Read at: PubMed - Published on 2/3/2025
Wolska A, Lloyd-Jones DM, Remaley AT. Measure Apolipoprotein B If We Believe What We Say About Precision Medicine. Circulation. 2025 Feb 04; 151(5):257-259. PMID: 39899636.
Read at: PubMed - Published on 2/3/2025
Zhao D, Yao J, Li Y, Jacobs DR, Zheng Y, Liu C, Fu Y, Deangelis MM, Lloyd-Jones D, Hou L, Zhang K. Associations of long-term exposure to temperature with coronary artery calcification risk among middle-aged adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study. Sci Total Environ. 2025 Feb 25; 966:178675. PMID: 39904207.
Read at: PubMed
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