Arjun Guha, PhD

Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Research Interests: Cell fate specification and cellular plasticity in lung development and repair, Non-classical stem cell hierarchies, Pulmonary neuroepithelial cells and their microenvironment, and Notch signaling

Publications

  • Published 12/12/2024

    Joy N, Deshpande A, Lingamallu SM, Prabantu VM, Naveenkumar CN, Bharathkumar K, Bhat S, Alvarado-Martinez Z, Livraghi-Butrico A, Hagood JS, Boucher RC, Lafkas D, Byrd KM, Narayanan S, Shandil RK, Guha A. Notch signaling stabilizes lengths of motile cilia in multiciliated cells in the lung. bioRxiv. 2024 Dec 12. PMID: 39713474.

    Read at: PubMed

  • Published 8/24/2024

    Lingamallu SM, Deshpande A, Joy N, Ganeshan K, Ray N, Ladher RK, Taketo MM, Lafkas D, Guha A. Neuroepithelial bodies and terminal bronchioles are niches for distinctive club cells that repair the airways following acute notch inhibition. Cell Rep. 2024 Sep 24; 43(9):114654. PMID: 39182223.

    Read at: PubMed

  • Published 5/1/2022

    Sain Basu D, Bhavsar R, Gulami I, Chavda S, Lingamallu SM, Muddashetty R, Veeranna C, Chattarji S, Thimmulappa R, Bhattacharya A, Guha A. FMRP protects the lung from xenobiotic stress by facilitating the integrated stress response. J Cell Sci. 2022 05 01; 135(9). PMID: 35319067.

    Read at: PubMed

  • Published 10/8/2021

    Kizhedathu A, Chhajed P, Yeramala L, Sain Basu D, Mukherjee T, Vinothkumar KR, Guha A. Duox-generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts. Elife. 2021 10 08; 10. PMID: 34622778.

    Read at: PubMed

  • Published 9/2/2020

    Kizhedathu A, Kunnappallil RS, Bagul AV, Verma P, Guha A. Multiple Wnts act synergistically to induce Chk1/Grapes expression and mediate G2 arrest in Drosophila tracheoblasts. Elife. 2020 09 02; 9. PMID: 32876044.

    Read at: PubMed

Other Positions

  • Member, Evans Center for Interdisciplinary Biomedical Research
    Boston University

Education

  • Manipal University, PhD
  • Wabash College, BS