Andrei A. Sharov, MD, PhD

Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Andrey Sharov, MD, PhD is an Assistant Professor of Dermatology at the Chobanian and Avedisian School of Medicine. He received his postdoctoral training her after completing his graduate degrees in Russia. Dr. Sharov is studying molecular mechanisms of skin development, with particular emphasis on the regulation and maintenance of adult stem cells in the skin. His research focuses on dissecting the signal transduction pathways which regulate stem cell quiescence to better understand how alterations in these signaling pathways contribute to melanoma and non-melanoma skin cancers. In addition, Dr. Sharov studies a role of higher-order chromatin organization in the process of pigmentation funded by NIH/NIAMS.

Publications

  • Published 10/31/2025

    Athar F, Morandini F, Fatima I, Silvestri I, Kim SJ, Lee M, Liao X, Sharov A, Botchkarev V, Seluanov A, Gorbunova V. African spiny mice show resistance to DMBA/TPA-induced squamous carcinogenesis with distinct benign tumor profile. Protein Cell. 2025 Oct 31; 16(10):896-904. PMID: 40119780.

    Read at: PubMed

  • Published 6/1/2025

    Hong J, Pham TX, Lee J, Raslan AA, Nicolas K, Sharov A, Meridew JA, Urrutia RA, Lomberk G, Huang SK, Ligresti G. Targeting the Epigenetic Regulator CBX5 Promotes Fibroblast Metabolic Reprogramming and Inhibits Lung Fibrosis. Am J Respir Cell Mol Biol. 2025 Jun; 72(6):627-642. PMID: 39642371.

    Read at: PubMed

  • Published 8/25/2023

    Kida M, Fatima I, Rozhkova E, Otero-Viñas M, Wu M, Kalin JH, Cole PA, Falanga V, Alani RM, Sharov AA. Inhibition of the CoREST Repressor Complex Promotes Wound Re-Epithelialization through the Regulation of Keratinocyte Migration. J Invest Dermatol. 2024 Feb; 144(2):378-386.e2. PMID: 37633457.

    Read at: PubMed

  • Published 4/11/2023

    Botchkarev VA, Fessing MY, Sharov AA. Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation. J Invest Dermatol. 2023 Jul; 143(7):1117-1120. PMID: 37045617.

    Read at: PubMed

  • Published 1/11/2023

    Chen GD, Fatima I, Xu Q, Rozhkova E, Fessing MY, Mardaryev AN, Sharov AA, Xu GL, Botchkarev VA. DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation. Sci Adv. 2023 Jan 13; 9(2):eabo7605. PMID: 36630508.

    Read at: PubMed

View All 30 Publications:   View Full Profile in BUMC

Other Positions

  • Member, Genome Science Institute
    Boston University

Websites

Education

  • Chuvash State University, MD
  • Chuvash State University, PhD

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