Andrei A. Sharov, MD, PhD
Assistant Professor, Dermatology
Biography
Andrey Sharov, MD, PhD is an Assistant Professor of Dermatology at the Chobanian and Avedisian School of Medicine. He received his postdoctoral training her after completing his graduate degrees in Russia. Dr. Sharov is studying molecular mechanisms of skin development, with particular emphasis on the regulation and maintenance of adult stem cells in the skin. His research focuses on dissecting the signal transduction pathways which regulate stem cell quiescence to better understand how alterations in these signaling pathways contribute to melanoma and non-melanoma skin cancers. In addition, Dr. Sharov studies a role of higher-order chromatin organization in the process of pigmentation funded by NIH/NIAMS.
Other Positions
- Member, Genome Science Institute, Boston University
Education
- Chuvash State University, MD
- Chuvash State University, PhD
Publications
- Published on 12/6/2024
Hong J, Pham TX, Lee J, Raslan AA, Nicolas K, Sharov A, Meridew JA, Urrutia RA, Lomberk G, Huang SK, Ligresti G. Targeting the Epigenetic Regulator CBX5 Promotes Fibroblast Metabolic Reprogramming and Inhibits Lung Fibrosis. Am J Respir Cell Mol Biol. 2024 Dec 06. PMID: 39642371.
Read at: PubMed - Published on 7/5/2012
Botchkarev VA, Gdula MR, Mardaryev AN, Sharov AA, Fessing MY. Epigenetic regulation of gene expression in keratinocytes. J Invest Dermatol. 2012 Nov; 132(11):2505-21. PMID: 22763788.
Read at: PubMed - Published on 12/1/2004
Botchkarev VA, Sharov AA. BMP signaling in the control of skin development and hair follicle growth. Differentiation. 2004 Dec; 72(9-10):512-26. PMID: 15617562.
Read at: PubMed - Published on 9/1/2004
Sharov AA, Siebenhaar F, Sharova TY, Botchkareva NV, Gilchrest BA, Botchkarev VA. Fas signaling is involved in the control of hair follicle response to chemotherapy. Cancer Res. 2004 Sep 1; 64(17):6266-70. PMID: 15342414.
Read at: PubMed - Published on 6/16/2003
Sharov AA, Weiner L, Sharova TY, Siebenhaar F, Atoyan R, Reginato AM, McNamara CA, Funa K, Gilchrest BA, Brissette JL, Botchkarev VA. Noggin overexpression inhibits eyelid opening by altering epidermal apoptosis and differentiation. EMBO J. 2003 Jun 16; 22(12):2992-3003. PMID: 12805214.
Read at: PubMed - Published on 1/1/2003
Sharov AA, Li GZ, Palkina TN, Sharova TY, Gilchrest BA, Botchkarev VA. Fas and c-kit are involved in the control of hair follicle melanocyte apoptosis and migration in chemotherapy-induced hair loss. J Invest Dermatol. 2003 Jan; 120(1):27-35. PMID: 12535195.
Read at: PubMed - Published on 1/1/2002
Botchkarev VA, Botchkareva NV, Sharov AA, Funa K, Huber O, Gilchrest BA. Modulation of BMP signaling by noggin is required for induction of the secondary (nontylotrich) hair follicles. J Invest Dermatol. 2002 Jan; 118(1):3-10. PMID: 11851869.
Read at: PubMed