Andrei A. Sharov, MD, PhD

Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Andrey Sharov, MD, PhD is an Assistant Professor of Dermatology at the Chobanian and Avedisian School of Medicine. He received his postdoctoral training her after completing his graduate degrees in Russia. Dr. Sharov is studying molecular mechanisms of skin development, with particular emphasis on the regulation and maintenance of adult stem cells in the skin. His research focuses on dissecting the signal transduction pathways which regulate stem cell quiescence to better understand how alterations in these signaling pathways contribute to melanoma and non-melanoma skin cancers. In addition, Dr. Sharov studies a role of higher-order chromatin organization in the process of pigmentation funded by NIH/NIAMS.

Publications

  • Published 3/22/2025

    Athar F, Morandini F, Fatima I, Silvestri I, Kim SB, Lee M, Liao X, Sharov A, Botchkarev V, Seluanov A, Gorbunova V. African spiny mice show resistance to DMBA/TPA-induced squamous carcinogenesis with distinct benign tumor profile. Protein Cell. 2025 Mar 22. PMID: 40119780.

    Read at: PubMed

  • Published 12/6/2024

    Hong J, Pham TX, Lee J, Raslan AA, Nicolas K, Sharov A, Meridew JA, Urrutia RA, Lomberk G, Huang SK, Ligresti G. Targeting the Epigenetic Regulator CBX5 Promotes Fibroblast Metabolic Reprogramming and Inhibits Lung Fibrosis. Am J Respir Cell Mol Biol. 2024 Dec 06. PMID: 39642371.

    Read at: PubMed

  • Published 7/5/2012

    Botchkarev VA, Gdula MR, Mardaryev AN, Sharov AA, Fessing MY. Epigenetic regulation of gene expression in keratinocytes. J Invest Dermatol. 2012 Nov; 132(11):2505-21. PMID: 22763788.

    Read at: PubMed

  • Published 12/1/2004

    Botchkarev VA, Sharov AA. BMP signaling in the control of skin development and hair follicle growth. Differentiation. 2004 Dec; 72(9-10):512-26. PMID: 15617562.

    Read at: PubMed

  • Published 9/1/2004

    Sharov AA, Siebenhaar F, Sharova TY, Botchkareva NV, Gilchrest BA, Botchkarev VA. Fas signaling is involved in the control of hair follicle response to chemotherapy. Cancer Res. 2004 Sep 1; 64(17):6266-70. PMID: 15342414.

    Read at: PubMed

Other Positions

  • Member, Genome Science Institute
    Boston University

Education

  • Chuvash State University, MD
  • Chuvash State University, PhD