Alice K. Jacobs, MD

Emeritus Professor, Medicine

Alice Jacobs
72 E. Concord Street


Alice K. Jacobs, MD, FACC, FAHA, MSCAI is a Professor of Medicine at Chobanian and Avedisian School of Medicine and served as the Director of the Cardiac Catheterization Laboratories and Interventional Cardiology for 20 years until 2011. She is currently Vice Chair for Clinical Affairs in the Department of Medicine at Boston University Medical Center and maintains an active clinical practice. Dr. Jacobs has led the American Heart Association’s Mission: Lifeline, a community-based, national initiative to develop systems of care for ST-segment elevation myocardial infarction (STEMI) patients and to increase the number of patients with timely access to primary percutaneous coronary intervention. Mission: Lifeline has now expanded to include Out-of-Hospital Cardiac Arrest and Stroke systems of care. Dr. Jacobs served as president of the American Heart Association in 2004-05 and as president of the Association of University Cardiologists in 2011. She is a past chair of the ACC/AHA Task Force on Practice Guidelines. During her tenure, the guidelines process and methodology evolved to include formal systematic evidence reviews, inclusion of patient representatives and lay members on guideline committees, incorporation of an Evidence Grading Tool, and further enhancements to the Class of Recommendation/Level of Evidence schema. Dr. Jacobs is a prior member of CMS MEDCAC and the IOM Committee on Social Security Cardiovascular Disability. Currently, she is the immediate past-chair of the American Board of Internal Medicine Interventional Cardiology Self-Assessment Test Committee, a member of NHLBI Cardiothoracic Surgical Network Protocol Review Committee and a member of the New York State Cardiac Advisory Committee. Her major research interest is in coronary revascularization strategies and sex-based difference in ischemic heart disease.

Expertise includes: Interventional Cardiology; Coronary revascularization; Sex-based differences in cardiovascular disease.

Other Positions

  • Vice Chair for Clinical Affairs, Medicine, Boston University Chobanian & Avedisian School of Medicine
  • Member, Whitaker Cardiovascular Institute, Boston University
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University


  • Saint Louis University, MD
  • State University of New York at Buffalo, BA


  • Published on 2/12/2024

    Elkind MSV, Arnett DK, Benjamin IJ, Eckel RH, Grant AO, Houser SR, Jacobs AK, Jones DW, Robertson RM, Sacco RL, Smith SC, Weisfeldt ML, Wu JC, Jessup M. The American Heart Association at 100: A Century of Scientific Progress and the Future of Cardiovascular Science: A Presidential Advisory From the American Heart Association. Circulation. 2024 Mar 19; 149(12):e964-e985. PMID: 38344851.

    Read at: PubMed
  • Published on 12/14/2023

    Hannan EL, Wu Y, Harik L, Tamis-Holland J, Jacobs AK, Chikwe J, Cozzens KS, Gaudino M. Coronary artery bypass surgery versus percutaneous interventions for women with multivessel coronary artery disease. J Thorac Cardiovasc Surg. 2023 Dec 14. PMID: 38101766.

    Read at: PubMed
  • Published on 9/8/2023

    Hannan EL, Zhong Y, Cozzens K, Ling FSK, Jacobs AK, King SB, Tamis-Holland J, Venditti FJ, Berger PB. New York Risk Model and Simplified Risk Score for In-Hospital/30-Day Mortality for Percutaneous Coronary Intervention. Am J Cardiol. 2023 Nov 01; 206:23-30. PMID: 37677879.

    Read at: PubMed
  • Published on 9/5/2023

    Henry TD, Baron SJ, Jacobs AK. STEMI-Related Mortality: Don't Stop Believin'. J Am Coll Cardiol. 2023 Sep 05; 82(10):1011-1013. PMID: 37648351.

    Read at: PubMed
  • Published on 7/24/2023

    Hannan EL, Zhong Y, Cozzens K, Jacobs AK, King SB, Tamis-Holland J, Ling FSK, Walford G, Venditti FJ, Berger PB, Rocha R. Ad Hoc Percutaneous Coronary Intervention in Stable Patients With Multivessel or Unprotected Left Main Disease. JACC Cardiovasc Interv. 2023 Jul 24; 16(14):1733-1742. PMID: 37495348.

    Read at: PubMed
  • Published on 7/17/2023

    Osho A, Fernandes MF, Poudel R, de Lemos J, Hong H, Zhao J, Li S, Thomas K, Kikuchi DS, Zegre-Hemsey J, Ibrahim N, Shah NS, Hollowell L, Tamis-Holland J, Granger CB, Cohen M, Henry T, Jacobs AK, Jollis JG, Yancy CW, Goyal A. Race-Based Differences in ST-Segment-Elevation Myocardial Infarction Process Metrics and Mortality From 2015 Through 2021: An Analysis of 178 062 Patients From the American Heart Association Get With The Guidelines-Coronary Artery Disease Registry. Circulation. 2023 Jul 18; 148(3):229-240. PMID: 37459415.

    Read at: PubMed
  • Published on 6/20/2023

    Ayalon N, Jacobs AK. Enhancing Regional ST-Segment-Elevation Myocardial Infarction Care: A Shock to the System. Circ Cardiovasc Interv. 2023 Jun; 16(6):e013177. PMID: 37339238.

    Read at: PubMed
  • Published on 4/1/2023

    Hannan EL, Zhong Y, Cozzens K, Osinaga A, Efferen L, Jacobs AK, Ling FSK, Gary W, Venditti FJ, Berger PB, Tamis-Holland J, King SB. Impact of COVID-19 on percutaneous coronary intervention utilization and mortality in New York. Catheter Cardiovasc Interv. 2023 May; 101(6):980-994. PMID: 37002950.

    Read at: PubMed
  • Published on 11/22/2022

    Jollis JG, Granger CB, Zègre-Hemsey JK, Henry TD, Goyal A, Tamis-Holland JE, Roettig ML, Ali MJ, French WJ, Poudel R, Zhao J, Stone RH, Jacobs AK. Treatment Time and In-Hospital Mortality Among Patients With ST-Segment Elevation Myocardial Infarction, 2018-2021. JAMA. 2022 Nov 22; 328(20):2033-2040. PMID: 36335474.

    Read at: PubMed
  • Published on 11/12/2022

    French WJ, Gunderson M, Travis D, Bieniarz M, Zegre-Hemsey J, Goyal A, Jacobs AK. Emergency Interhospital Transfer of Patients With ST-Segment-Elevation Myocardial Infarction: Call 9-1-1-The American Heart Association Mission: Lifeline Program. J Am Heart Assoc. 2022 Nov 15; 11(22):e026700. PMID: 36370009.

    Read at: PubMed

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