Vasan S. Ramachandran, MD

Professor, Medicine

Vasan Ramachandran
(617) 638-8090
801 Massachusetts Ave Crosstown Center

Biography

Vasan S. Ramachandran, M.D., Principal Investigator and Director of the FHS, and Director of the FHS fellowship program in cardiovascular epidemiology for the last 25 years.

Dr. Ramachandran is a Professor of Medicine and Epidemiology at BUSM/BUSPH, and Chief, Section of Preventive Medicine and Epidemiology, Department of Medicine, BUSM. He is the Jay & Louis Coffman Professor of Vascular Medicine at BUSM. Dr. Ramachandran is a trained cardiologist with subspecialty training in echocardiography. He is a fellow of the AHA Councils on Epidemiology and Prevention and Functional Genomics and Translational Biology, and a fellow of the American College of Cardiology (ACC). He has extensive experience in supervising trainees at many levels and *teaches the foundational core course on Cardiovascular Epidemiology at BUSPH (EP751) that all trainees of this program will take*. He has several active R01 grants from the NHLBI/NIDDK and received two K24 Mid-Career Investigator mentoring grants from the NHLBI. He has mentored several K23 awardees, and is currently the primary mentor for four K23 awardees and a K99R00 grantee (junior faculty mentors-in-training in this program). Overall, he has supervised over 60 trainees during the past 20 years; most are in key positions in academia. He received the Outstanding Mentor awards from the Department of Medicine, BUSM, and the AHA Council on Epidemiology and Prevention, and the prestigious AHA Population Science
Award in 2014.

Importantly, Dr. Ramachandran’s own peer-reviewed funding spans thematic areas of genetics and genomics, cardiac and vascular remodeling, novel biomarkers, systems biology including proteomics and metabolomics, and stem cell biology. He has a 25-year history in research in cardiovascular epidemiology, including the two years he trained as a FHS fellow (1993-1995). He established the first School of Public Health in India between 1996-1998, serving as its inaugural director and the coordinator of its MPH program. He is the founding member and leader of the international EchoGen consortium, and chairs the Steering Committee of the Chronic Kidney Disease Biomarker Consortium funded by the NIDDK (U01DK085689). He is recognized internationally for translational research in cardiovascular epidemiology and lectures regularly at the AHA early career session on “how to develop a career in translational research and epidemiology/genetics.” He is well equipped to mentor trainees about grant writing having been a member of the Cardiovascular and Sleep (CASE) SRG, and an active reviewer of grants for national and international funding agencies. He served for many years on the NHLBI panel for reviewing K23-K24-K25 career development grants. He is well qualified to mentor trainees in best publication practices and has served until recently as an Associate Editor for *Circulation*, and the Editor-in-Chief of *Circulation: Cardiovascular Genetics*. He works collaboratively with the Center for Translational Epidemiology and Comparative Effectiveness Research within the Department of Medicine, BUSM, that hosts multiple epidemiological datasets, including from multiple cohort studies, national surveys (NHANES), administrative databases and electronic health records; this center will be a valuable data source for trainees.

Other Positions

  • Section Chief, Preventive Medicine & Epidemiology, Medicine, Boston University School of Medicine
  • Jay & Louis Coffman Professor of Vascular Medicine , Medicine, Boston University School of Medicine
  • Director, Echocardiography/Vascular Laboratory, Framingham Heart Study
  • Mentor for Graduate Medical Students, Boston University School of Medicine, Division of Graduate Medical Sciences

Education

  • All India Institute of Medical Science (AIIMS), MD
  • All India Institute of Medical Science (AIIMS), MBBS
  • All India Institute of Medical Science (AIIMS), DM

Classes Taught

  • SPH EP751

Publications

  • Published on 10/15/2017

    Zakharov MN, Bhasin S, Travison TG, Xue R, Ulloor J, Ramachandran V, Carter E, Wu F, Jasuja R. Corrigendum to "A multi-step, allosteric model of testosterone's binding to sex hormone binding globulin" [Mol. Cell. Endocrinol. 399 (2015) 190-200]. Mol Cell Endocrinol. 2017 Oct 15; 454:167. PMID: 28780939.

    Read at: PubMed
  • Published on 10/7/2017

    Fetterman JL, Liu C, Mitchell GF, Ramachandran VS, Benjamin EJ, Vita JA, Hamburg NM, Levy D. Relations of mitochondrial genetic variants to measures of vascular function. Mitochondrion. 2017 Oct 07. PMID: 28993255.

    Read at: PubMed
  • Published on 9/9/2017

    Vasan RS, Xanthakis V, Lyass A, Andersson C, Tsao C, Cheng S, Aragam J, Benjamin EJ, Larson MG. Epidemiology of Left Ventricular Systolic Dysfunction and Heart Failure in the Framingham Study: An Echocardiographic Study Over 3 Decades. JACC Cardiovasc Imaging. 2017 Sep 09. PMID: 28917679.

    Read at: PubMed
  • Published on 8/1/2017

    Niiranen TJ, McCabe EL, Larson MG, Henglin M, Lakdawala NK, Vasan RS, Cheng S. Risk for hypertension crosses generations in the community: a multi-generational cohort study. Eur Heart J. 2017 Aug 01; 38(29):2300-2308. PMID: 28430902.

    Read at: PubMed
  • Published on 8/1/2017

    Jasuja GK, Travison TG, Murabito JM, Davda MN, Rose AJ, Basaria S, Coviello A, Vasan RS, D'Agostino R, Bhasin S. Circulating Estrogen Levels and Self-Reported Health and Mobility Limitation in Community-Dwelling Men of the Framingham Heart Study. J Gerontol A Biol Sci Med Sci. 2017 Aug 01; 72(8):1137-1142. PMID: 28329787.

    Read at: PubMed
  • Published on 6/1/2017

    Tan ZS, Spartano NL, Beiser AS, DeCarli C, Auerbach SH, Vasan RS, Seshadri S. Physical Activity, Brain Volume, and Dementia Risk: The Framingham Study. J Gerontol A Biol Sci Med Sci. 2017 Jun 01; 72(6):789-795. PMID: 27422439.

    Read at: PubMed
  • Published on 6/1/2017

    Jensen MK, Jensen RA, Mukamal KJ, Guo X, Yao J, Sun Q, Cornelis M, Liu Y, Chen MH, Kizer JR, Djoussé L, Siscovick DS, Psaty BM, Zmuda JM, Rotter JI, Garcia M, Harris T, Chen I, Goodarzi MO, Nalls MA, Keller M, Arnold AM, Newman AB, Hoogeveen RC, Rexrode KM, Rimm EB, Hu FB, Ramachandran VS, Katz R, Pankow JS, Ix JH. Detection of genetic loci associated with plasma fetuin-A: a meta-analysis of genome-wide association studies from the CHARGE Consortium. Hum Mol Genet. 2017 Jun 01; 26(11):2156-2163. PMID: 28379451.

    Read at: PubMed
  • Published on 5/30/2017

    Niiranen TJ, Lyass A, Larson MG, Hamburg NM, Benjamin EJ, Mitchell GF, Vasan RS. Prevalence, Correlates, and Prognosis of Healthy Vascular Aging in a Western Community-Dwelling Cohort: The Framingham Heart Study. Hypertension. 2017 Aug; 70(2):267-274. PMID: 28559398.

    Read at: PubMed
  • Published on 5/26/2017

    Tragante V, Gho JMIH, Felix JF, Vasan RS, Smith NL, Voight BF, Palmer C, van der Harst P, Moore JH, Asselbergs FW. Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype. BioData Min. 2017; 10:18. PMID: 28559929.

    Read at: PubMed
  • Published on 5/12/2017

    Niiranen TJ, McCabe EL, Larson MG, Henglin M, Lakdawala NK, Vasan RS, Cheng S. Heritability and risks associated with early onset hypertension: multigenerational, prospective analysis in the Framingham Heart Study. BMJ. 2017 May 12; 357:j1949. PMID: 28500036.

    Read at: PubMed

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