Shinobu Matsuura, DVM, PhD

Assistant Professor, Medicine

Shinobu Matsuura
617.358.8245
700 Albany St Ctr for Adv Biomed Res

Biography

Shinobu Matsuura, DVM, PhD, graduated Veterinary School and completed her clinical training at the Residency Program for Internal Medicine at the University of São Paulo (USP), Brazil. Her interest in basic research led her to pursue graduate studies at the University of Tokyo, Japan, under the guidance of Dr. Hajime Tsujimoto, and postdoctoral training at the laboratory of Dr. Dong-Er Zhang at the Scripps Research Institute and at the University of California, San Diego.

Dr. Matsuura joined the laboratory of Dr. Katya Ravid at Boston University in 2011 as a postdoctoral fellow, becoming Instructor of Medicine in 2016 and Assistant Professor in 2021. Dr. Matsuura is a PI of the career development SERCA K01 award, from the Office of Research Infrastructure (ORIP)/NIH, a training mechanism specifically designed for veterinarians pursuing basic research.

Dr. Matsuura has a career-long interest in hematology research, which emerged from her experience treating canine patients with hematological malignancies. She has multiple first author and co-author publications in the journal Blood, a leading journal in the field of hematology. Dr. Matsuura’s major research focus is stem cell biology and the mechanisms of cell differentiation, or, more precisely, the de-regulation of those processes in malignancy. Dr. Matsuura’s strength lies in her ability to combine clinical and basic science knowledge to make the most effective use of animal models to carry out preclinical research of significant translational potential.

Websites

Education

  • University of Tokyo, PhD
  • Universidade de São Paulo, DVM

Publications

  • Published on 7/8/2022

    Karagianni A, Matsuura S, Gerstenfeld LC, Ravid K. Inhibition of Osteoblast Differentiation by JAK2V617F Megakaryocytes Derived From Male Mice With Primary Myelofibrosis. Front Oncol. 2022; 12:929498. PMID: 35880162.

    Read at: PubMed
  • Published on 12/21/2021

    Matsuura S, Balduini A, Onisto M. Editorial: Mechanisms of Cell Adhesion in Hematopoietic Stem Cells. Front Cell Dev Biol. 2021; 9:826554. PMID: 34993206.

    Read at: PubMed
  • Published on 12/12/2021

    Yang X, Chitalia SV, Matsuura S, Ravid K. Integrins and their role in megakaryocyte development and function. Exp Hematol. 2022 02; 106:31-39. PMID: 34910941.

    Read at: PubMed
  • Published on 9/15/2021

    Lim KH, Matsuura S, Xu B. Editorial: Novel Treatment Strategies for Myeloproliferative Neoplasms. Front Oncol. 2021; 11:762928. PMID: 34604100.

    Read at: PubMed
  • Published on 8/20/2020

    Matsuura S, Thompson CR, Belghasem ME, Bekendam RH, Piasecki A, Leiva O, Ray A, Italiano J, Yang M, Merill-Skoloff G, Chitalia VC, Flaumenhaft R, Ravid K. Platelet Dysfunction and Thrombosis in JAK2V617F-Mutated Primary Myelofibrotic Mice. Arterioscler Thromb Vasc Biol. 2020 10; 40(10):e262-e272. PMID: 32814440.

    Read at: PubMed
  • Published on 6/18/2020

    Matsuura S, Thompson CR, Ng SK, Ward CM, Karagianni A, Mazzeo C, Malara A, Balduini A, Ravid K. Adhesion to fibronectin via a5ß1 integrin supports expansion of the megakaryocyte lineage in primary myelofibrosis. Blood. 2020 06 18; 135(25):2286-2291. PMID: 32294178.

    Read at: PubMed
  • Published on 10/21/2019

    Leiva O, Ng SK, Matsuura S, Chitalia V, Lucero H, Findlay A, Turner C, Jarolimek W, Ravid K. Novel lysyl oxidase inhibitors attenuate hallmarks of primary myelofibrosis in mice. Int J Hematol. 2019 Dec; 110(6):699-708. PMID: 31637674.

    Read at: PubMed
  • Published on 9/18/2019

    Sano S, Wang Y, Yura Y, Sano M, Oshima K, Yang Y, Katanasaka Y, Min KD, Matsuura S, Ravid K, Mohi G, Walsh K. JAK2V617F -Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure. JACC Basic Transl Sci. 2019 Oct; 4(6):684-697. PMID: 31709318.

    Read at: PubMed
  • Published on 1/17/2018

    Kolachalama VB, Shashar M, Alousi F, Shivanna S, Rijal K, Belghasem ME, Walker J, Matsuura S, Chang GH, Gibson CM, Dember LM, Francis JM, Ravid K, Chitalia VC. Uremic Solute-Aryl Hydrocarbon Receptor-Tissue Factor Axis Associates with Thrombosis after Vascular Injury in Humans. J Am Soc Nephrol. 2018 03; 29(3):1063-1072. PMID: 29343519.

    Read at: PubMed
  • Published on 11/22/2017

    Shashar M, Belghasem ME, Matsuura S, Walker J, Richards S, Alousi F, Rijal K, Kolachalama VB, Balcells M, Odagi M, Nagasawa K, Henderson JM, Gautam A, Rushmore R, Francis J, Kirchhofer D, Kolandaivelu K, Sherr DH, Edelman ER, Ravid K, Chitalia VC. Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk. Sci Transl Med. 2017 Nov 22; 9(417). PMID: 29167396.

    Read at: PubMed

View 27 more publications: View full profile at BUMC

View all profiles