Robert A. Stern, PhD

Professor, Neurology

Robert Stern
617.358.5375
72 E. Concord St Robinson (B)

Biography

I am Co-Founder and Director of Clinical Research for the Boston University (BU) Chronic Traumatic Encephalopathy (CTE) Center. A major focus of my current research is on the long-term consequences of repetitive head impacts, including the neuropathological, risk factors (e.g., genetic and head impact exposure), neuroimaging, biomarker development, and clinical diagnosis and descriptions of the neurodegenerative disease, CTE. I am currently lead PI of an NINDS-funded, 7-year, multicenter project examining these issues. From 2010-2019, I was the Clinical Core Director of the NIA-funded BU Alzheimer’s Disease Center (BU ADC); I remain a Senior Investigator for the BU ADC. In these roles, I have been honored to oversee a multidisciplinary group of talented scientists and clinicians and direct the center’s longitudinal research registry, as well as several NIH- and industry-funded diagnostic, prevention, and treatment trials. Other areas of my research program include the diagnosis, risk factors, and treatment of cognitive decline and neuropsychiatric dysfunction in aging. I have also published extensively on the psychometric properties of many widely used tests in neuropsychology, as well as the use of various instruments and biomarkers in the differential diagnosis of Alzheimer’s disease (AD) and AD Related Dementias (ADRD). In addition, I have developed several commonly used tests and instruments, including the Neuropsychological Assessment Battery (NAB). I have had leadership positions in several training programs, have mentored over 40 trainees, and play a key role in the professional development of junior faculty in the BU School of Medicine (BUSM).

Other Positions

  • Professor, Anatomy & Neurobiology, Boston University School of Medicine
  • Professor, Neurosurgery, Boston University School of Medicine
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences
  • Director of Clinical Research, Chronic Traumatic Encephalopathy Center, Boston University School of Medicine

Education

  • University of Rhode Island, PhD
  • University of Rhode Island, MA
  • Wesleyan University, BA

Classes Taught

  • GMSMS703

Publications

  • Published on 8/1/2022

    Atherton K, Han X, Chung J, Cherry JD, Baucom Z, Saltiel N, Nair E, Abdolmohammadi B, Uretsky M, Khan MM, Shea C, Durape S, Martin BM, Palmisano JN, Farrell K, Nowinski CJ, Alvarez VE, Dwyer B, Daneshvar DH, Katz DI, Goldstein LE, Cantu RC, Kowall NW, Alosco ML, Huber BR, Tripodis Y, Crary JF, Farrer L, Stern RA, Stein TD, McKee AC, Mez J. Association of APOE Genotypes and Chronic Traumatic Encephalopathy. JAMA Neurol. 2022 Aug 01; 79(8):787-796. PMID: 35759276.

    Read at: PubMed
  • Published on 5/13/2022

    Morrison MS, Aparicio HJ, Blennow K, Zetterberg H, Ashton NJ, Karikari TK, Tripodis Y, Martin B, Palmisano JN, Sugarman MA, Frank B, Steinberg EG, Turk KW, Budson AE, Au R, Goldstein LE, Jun GR, Kowall NW, Killiany R, Qiu WQ, Stern RA, Mez J, McKee AC, Stein TD, Alosco ML. Antemortem plasma phosphorylated tau (181) predicts Alzheimer's disease neuropathology and regional tau at autopsy. Brain. 2022 May 13. PMID: 35554506.

    Read at: PubMed
  • Published on 4/20/2022

    Frank B, Ally M, Tripodis Y, Puzo C, Labriolo C, Hurley L, Martin B, Palmisano J, Chan L, Steinberg E, Turk K, Budson A, O'Connor M, Au R, Qiu WQ, Goldstein L, Kukull W, Kowall N, Killiany R, Stern R, Stein T, McKee A, Mez J, Alosco M. Trajectories of Cognitive Decline in Brain Donors With Autopsy-Confirmed Alzheimer Disease and Cerebrovascular Disease. Neurology. 2022 Jun 14; 98(24):e2454-e2464. PMID: 35444054.

    Read at: PubMed
  • Published on 4/1/2022

    Phelps A, Alosco ML, Baucom Z, Hartlage K, Palmisano JN, Weuve J, Mez J, Tripodis Y, Stern RA. Association of Playing College American Football With Long-term Health Outcomes and Mortality. JAMA Netw Open. 2022 Apr 01; 5(4):e228775. PMID: 35442450.

    Read at: PubMed
  • Published on 2/9/2022

    Turk KW, Geada A, Alvarez VE, Xia W, Cherry JD, Nicks R, Meng G, Daley S, Tripodis Y, Huber BR, Budson AE, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, Alosco ML, Mez J, McKee AC, Stein TD. A comparison between tau and amyloid-ß cerebrospinal fluid biomarkers in chronic traumatic encephalopathy and Alzheimer disease. Alzheimers Res Ther. 2022 02 09; 14(1):28. PMID: 35139894.

    Read at: PubMed
  • Published on 1/1/2022

    Foley ÉM, Tripodis Y, Yhang E, Koerte IK, Martin BM, Palmisano J, Makris N, Schultz V, Lepage C, Muehlmann M, Wróbel PP, Guenette JP, Cantu RC, Lin AP, Coleman M, Mez J, Bouix S, Shenton ME, Stern RA, Alosco ML. Quantifying and Examining Reserve in Symptomatic Former National Football League Players. J Alzheimers Dis. 2022; 85(2):675-689. PMID: 34864657.

    Read at: PubMed
  • Published on 12/7/2021

    Alosco ML, Mian AZ, Buch K, Farris CW, Uretsky M, Tripodis Y, Baucom Z, Martin B, Palmisano J, Puzo C, Ang TFA, Joshi P, Goldstein LE, Au R, Katz DI, Dwyer B, Daneshvar DH, Nowinski C, Cantu RC, Kowall NW, Huber BR, Alvarez VE, Stern RA, Stein TD, Killiany RJ, McKee AC, Mez J. Structural MRI profiles and tau correlates of atrophy in autopsy-confirmed CTE. Alzheimers Res Ther. 2021 12 07; 13(1):193. PMID: 34876229.

    Read at: PubMed
  • Published on 12/2/2021

    Frank B, Ally M, Brekke B, Zetterberg H, Blennow K, Sugarman MA, Ashton NJ, Karikari TK, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Simkina I, Turk KW, Budson AE, O'Connor MK, Au R, Goldstein LE, Jun GR, Kowall NW, Stein TD, McKee AC, Killiany R, Qiu WQ, Stern RA, Mez J, Alosco ML. Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau. Alzheimers Dement. 2021 Dec 02. PMID: 34854549.

    Read at: PubMed
  • Published on 12/1/2021

    Daneshvar DH, Mez J, Alosco ML, Baucom ZH, Mahar I, Baugh CM, Valle JP, Weuve J, Paganoni S, Cantu RC, Zafonte RD, Stern RA, Stein TD, Tripodis Y, Nowinski CJ, McKee AC. Incidence of and Mortality From Amyotrophic Lateral Sclerosis in National Football League Athletes. JAMA Netw Open. 2021 12 01; 4(12):e2138801. PMID: 34910152.

    Read at: PubMed
  • Published on 11/24/2021

    Uretsky M, Bouix S, Killiany RJ, Tripodis Y, Martin B, Palmisano J, Mian AZ, Buch K, Farris C, Daneshvar DH, Dwyer B, Goldstein L, Katz D, Nowinski C, Cantu R, Kowall N, Huber BR, Stern RA, Alvarez VE, Stein TD, McKee A, Mez J, Alosco ML. Association Between Antemortem FLAIR White Matter Hyperintensities and Neuropathology in Brain Donors Exposed to Repetitive Head Impacts. Neurology. 2022 01 04; 98(1):e27-e39. PMID: 34819338.

    Read at: PubMed

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