I am Co-Founder and Director of Clinical Research for the Boston University (BU) Chronic Traumatic Encephalopathy (CTE) Center. A major focus of my current research is on the long-term consequences of repetitive head impacts, including the neuropathological, risk factors (e.g., genetic and head impact exposure), neuroimaging, biomarker development, and clinical diagnosis and descriptions of the neurodegenerative disease, CTE. I am currently lead PI of an NINDS-funded, 7-year, multicenter project examining these issues. From 2010-2019, I was the Clinical Core Director of the NIA-funded BU Alzheimer’s Disease Center (BU ADC); I remain a Senior Investigator for the BU ADC. In these roles, I have been honored to oversee a multidisciplinary group of talented scientists and clinicians and direct the center’s longitudinal research registry, as well as several NIH- and industry-funded diagnostic, prevention, and treatment trials. Other areas of my research program include the diagnosis, risk factors, and treatment of cognitive decline and neuropsychiatric dysfunction in aging. I have also published extensively on the psychometric properties of many widely used tests in neuropsychology, as well as the use of various instruments and biomarkers in the differential diagnosis of Alzheimer’s disease (AD) and AD Related Dementias (ADRD). In addition, I have developed several commonly used tests and instruments, including the Neuropsychological Assessment Battery (NAB). I have had leadership positions in several training programs, have mentored over 40 trainees, and play a key role in the professional development of junior faculty in the BU School of Medicine (BUSM).
- Professor, Anatomy & Neurobiology, Boston University School of Medicine
- Professor, Neurosurgery, Boston University School of Medicine
- Director of Clinical Research, Chronic Traumatic Encephalopathy Center, Boston University School of Medicine
- Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences
- University of Rhode Island, PhD
- University of Rhode Island, MA
- Wesleyan University, BA
- Published on 10/13/2020
Wessels AM, Lines C, Stern RA, Kost J, Voss T, Mozley LH, Furtek C, Mukai Y, Aisen PS, Cummings JL, Tariot PN, Vellas B, Dupre N, Randolph C, Michelson D, Andersen SW, Shering C, Sims JR, Egan MF. Cognitive outcomes in trials of two BACE inhibitors in Alzheimer's disease. Alzheimers Dement. 2020 Oct 13. PMID: 33049114.
- Published on 10/1/2020
Alosco ML, Tripodis Y, Rowland B, Chua AS, Liao H, Martin B, Jarnagin J, Chaisson CE, Pasternak O, Karmacharya S, Koerte IK, Cantu RC, Kowall NW, McKee AC, Shenton ME, Greenwald R, McClean M, Stern RA, Lin A. A magnetic resonance spectroscopy investigation in symptomatic former NFL players. Brain Imaging Behav. 2020 Oct; 14(5):1419-1429. PMID: 30848432.
- Published on 9/17/2020
Adams JW, Alosco ML, Mez J, Alvarez VE, Huber BR, Tripodis Y, Adler CH, Kubilius C, Cormier KA, Mathais R, Nicks R, Kelley HJ, Saltiel N, Uretsky M, Nair E, Aytan N, Cherry JD, Nowinski CJ, Kowall NW, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, McKee AC, Stein TD. Association of probable REM sleep behavior disorder with pathology and years of contact sports play in chronic traumatic encephalopathy. Acta Neuropathol. 2020 Sep 17. PMID: 32939646.
- Published on 9/9/2020
Mez J, Stern RA, McKee AC. Chronic Traumatic Encephalopathy. Semin Neurol. 2020 Aug; 40(4):351-352. PMID: 32906179.
- Published on 8/11/2020
Alosco ML, Cherry JD, Huber BR, Tripodis Y, Baucom Z, Kowall NW, Saltiel N, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Palmisano JN, Martin B, Cantu RC, Stern RA, Alvarez VE, Mez J, Stein TD, McKee AC. Characterizing tau deposition in chronic traumatic encephalopathy (CTE): utility of the McKee CTE staging scheme. Acta Neuropathol. 2020 Oct; 140(4):495-512. PMID: 32778942.
- Published on 8/2/2020
Mariani M, Alosco ML, Mez J, Stern RA. Clinical Presentation of Chronic Traumatic Encephalopathy. Semin Neurol. 2020 Aug; 40(4):370-383. PMID: 32740900.
- Published on 7/16/2020
Phelps A, Mez J, Stern RA, Alosco ML. Risk Factors for Chronic Traumatic Encephalopathy: A Proposed Framework. Semin Neurol. 2020 08; 40(4):439-449. PMID: 32674182.
- Published on 6/26/2020
Alosco ML, Tripodis Y, Baucom ZH, Mez J, Stein TD, Martin B, Haller O, Conneely S, McClean M, Nosheny R, Mackin S, McKee AC, Weiner MW, Stern RA. Late contributions of repetitive head impacts and TBI to depression symptoms and cognition. Neurology. 2020 08 18; 95(7):e793-e804. PMID: 32591472.
- Published on 5/29/2020
Sugarman MA, Zetterberg H, Blennow K, Tripodis Y, McKee AC, Stein TD, Martin B, Palmisano JN, Steinberg EG, Simkin I, Budson AE, Killiany R, O'Connor MK, Au R, Qiu WWQ, Goldstein LE, Kowall NW, Mez J, Stern RA, Alosco ML. A longitudinal examination of plasma neurofilament light and total tau for the clinical detection and monitoring of Alzheimer's disease. Neurobiol Aging. 2020 Oct; 94:60-70. PMID: 32585491.
- Published on 5/28/2020
Campbell J, Howland J, Hess C, Nelson K, Stern RA, Torres A, Olshaker J. Disparities in baseline neurocognitive testing for student concussion management in Massachusetts high schools. BMJ Open Sport Exerc Med. 2020; 6(1):e000752. PMID: 32537243.
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