Michael L. Alosco, PhD

Associate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Alosco is a licensed clinical neuropsychologist and serves as the co-director of the Boston University Alzheimer’s Disease Research Center Clinical Core and is a lead investigator of the BU CTE Center. He also oversees Neuropsychology for the Memory and Aging Clinic at Boston Medical Center. He completed his undergraduate studies at Providence College and he earned his doctoral degree in clinical psychology, with a focus on neuropsychology, in 2015 from Kent State University. He completed his clinical internship in neuropsychology at the VA Boston Healthcare System. Dr. Alosco completed his post-doctoral studies in neuropsychology via NIH-funded training Awards (T32, F32) at the Boston University Alzheimer’s Disease Research Center and CTE Center. In 2018, he became an Assistant Professor of Neurology at the Chobanian and Avedisian School of Medicine and he was promoted to Associate Professor in 2019. Dr. Alosco has >150 peer-reviewed publications, is the PI of multiple NIH funded grants, is the recipient of an NIH/NINDS K23 Award, is the Project Lead of an NIH-funded multisite U54 grant, and serves as aco-investigator on numerous federal and non-federal funded grants. He has also written numerous book chapters, and he is the co-Editor of the Oxford Handbook of Adult Cognitive Disorders which was published by Oxford University Press in 2019.

Dr. Alosco has an active and established research program that has a thematic focus on three areas: (1) the relationship between repetitive head impacts (RHI) and traumatic brain injury (TBI) with a later-life cognitive and neuropsychiatric decline, as well as neurodegenerative disease(s); (2) the contribution of cerebrovascular disease to the clinical and neuropathological expression of CTE, AD, and AD-related dementias (ADRD); and (3) in vivo biomarker development for CTE, AD, and ADRD with a focus on tau PET imaging, structural MRI, and blood-based biomarkers.

Publications

  • Published 2/25/2026

    Emanuel OM, Miner AE, Lee SY, Matusz EF, Tanner JJ, Marsiske M, Holgerson A, Ly MT, Tuz-Zahra F, Tripodis Y, Adler CH, Balcer LJ, Bernick C, Zetterberg H, Blennow K, Ashton NJ, Peskind ER, Banks SJ, Barr WB, Wethe JV, Cantu RC, Coleman MJ, Dodick DW, McClean MD, Mez J, Palmisano J, Martin B, Lin AP, Pasternak O, Koerte IK, Cummings JL, Reiman EM, Shenton ME, Stern RA, Bouix S, Alosco ML, Asken BM. Inflammation, Limbic White Matter Microstructure, and Clinical Symptoms in Retired American Football Players With Repetitive Head Impacts. Neurology. 2026 Mar 24; 106(6):e214646. PMID: 41740080.

    Read at: PubMed

  • Published 2/22/2026

    Tao Q, Ang TFA, Huang J, Itchapurapu IS, Mez J, Alosco M, Au R, Farrer LA, Zhang X, Qiu WQ. Blood PCSK9 Impacts Alzheimer's Disease Risk in an APOE Genotype-Dependent Manner: A Prospective Cohort Study. Health Sci Rep. 2026 Feb; 9(2):e71810. PMID: 41737429.

    Read at: PubMed

  • Published 1/2/2026

    Burton R, Durape S, Price E, Chien-Young K, Joshi P, Yhang E, Liu Y, Devine S, Gurnani AS, Ang TFA, Katz DI, Alosco ML, Tripodis Y, Au R, Dams-O'Connor K, Mez J. Traumatic Brain Injury and All-Cause and Dementia-Related Mortality in the Framingham Heart Study. JAMA Netw Open. 2026 Jan 02; 9(1):e2555138. PMID: 41615690.

    Read at: PubMed

  • Published 9/22/2025

    Subramanian ML, Sampani K, Ness S, Tuz-Zahra F, Alluri S, Chen X, Siegel NH, Aytan N, Xia W, Tripodis Y, Alosco ML, Stein TD. Biomarkers for Alzheimer's disease are upregulated in patients with diabetic retinopathy. J Alzheimers Dis. 2025 Nov; 108(2):586-596. PMID: 40982223.

    Read at: PubMed

  • Published 9/11/2025

    Jung LB, Mirmajlesi AS, Stearns J, Breedlove K, John O, Kim N, Wickham A, Su Y, Protas H, Baucom ZH, Tuz-Zahra F, Tripodis Y, Daneshvar DH, Wiegand TLT, Billah T, Pasternak O, Heller C, Im BS, Datta S, Coleman MJ, Adler CH, Bernick C, Balcer LJ, Alosco ML, Lin AP, Cummings JL, Reiman EM, Stern RA, Shenton ME, Bouix S, Koerte IK, Arciniega H. Sulcal morphology in former American football players. Brain Commun. 2025; 7(5):fcaf345. PMID: 41048544.

    Read at: PubMed

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Websites

Education

  • Kent State University, PhD
  • Kent State University, MA
  • Providence College, BA

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