Michael L Alosco, PhD

Assistant Professor, Neurology

Alosco Michael
617.638.5351
72 E. Concord Street

Biography

Dr. Alosco completed his undergraduate studies at Providence College and he earned his doctoral degree in clinical psychology, with a focus in neuropsychology, in 2015 from Kent State University. He completed his clinical internship in neuropsychology at the VA Boston Healthcare System. In 2015, Dr. Alosco was awarded a post-doctoral fellowship at the Boston University (BU) Alzheimer’s Disease (AD) Center (ADC) and BU CTE Center through the NIA-funded Alzheimer’s Disease Translational Research Training Program (T32AG036697). In 2016, Dr. Alosco transitioned to a National Research Service Award (NRSA) F32 from the National Institute of Neurological Disorders and Stroke to continue his advanced clinical research training at the BU ADC and BU CTE Center. In 2018, he became an Assistant Professor of Neurology at the Boston University School of Medicine.

Dr. Alosco’s research focuses on risk factors and biomarkers of neurodegenerative conditions, with a focus on AD and CTE. Dr. Alosco is particularly interested in the contribution of cerebrovascular disease to the clinical and neuropathological presentation of AD and CTE. He is additionally involved in research examining the relationship between exposure to repetitive head impacts and long-term neurological consequences. He is mentored at the BU AD and CTE Center by Robert A. Stern, Ph.D., and Ann C. McKee, M.D.

In August 2018, he received a five-year K23 Award from the National Institutes of Health’s National Institute of Neurological Disorders and Stroke (NINDS). He will use MRI data and biomarkers to examine patterns of white matter alterations in former NFL players compared to healthy individuals as well as those with Alzheimer’s disease dementia. He will do so by leveraging ongoing studies at BUSM, including the NINDS-funded DIAGNOSE CTE Research Project and the National Institute on Aging (NIA) funded BU Alzheimer’s Disease Center (BU ADC). The K23 Award will additionally provide Dr. Alosco with advanced and cutting-edge training in CTE to facilitate his progression as an independent clinical neuroscientist.

Education

  • Kent State University, PhD
  • Kent State University, MA
  • Providence College, BA

Publications

  • Published on 11/23/2019

    Mez J, Daneshvar DH, Abdolmohammadi B, Chua AS, Alosco ML, Kiernan PT, Evers L, Marshall L, Martin BM, Palmisano JN, Nowinski CJ, Mahar I, Cherry JD, Alvarez VE, Dwyer B, Huber BR, Stein TD, Goldstein LE, Katz DI, Cantu RC, Au R, Kowall NW, Stern RA, McClean MD, Weuve J, Tripodis Y, McKee AC. Duration of American Football Play and Chronic Traumatic Encephalopathy. Ann Neurol. 2020 Jan; 87(1):116-131. PMID: 31589352.

    Read at: PubMed
  • Published on 8/5/2019

    Alosco ML, Stein TD, Tripodis Y, Chua AS, Kowall NW, Huber BR, Goldstein LE, Cantu RC, Katz DI, Palmisano JN, Martin B, Cherry JD, Mahar I, Killiany RJ, McClean MD, Au R, Alvarez V, Stern RA, Mez J, McKee AC. Association of White Matter Rarefaction, Arteriolosclerosis, and Tau With Dementia in Chronic Traumatic Encephalopathy. JAMA Neurol. 2019 Aug 05. PMID: 31380975.

    Read at: PubMed
  • Published on 7/27/2019

    Puzo C, Labriola C, Sugarman MA, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Stein TD, Kowall NW, McKee AC, Mez J, Killiany RJ, Stern RA, Alosco ML. Independent effects of white matter hyperintensities on cognitive, neuropsychiatric, and functional decline: a longitudinal investigation using the National Alzheimer's Coordinating Center Uniform Data Set. Alzheimers Res Ther. 2019 Jul 27; 11(1):64. PMID: 31351489.

    Read at: PubMed
  • Published on 6/10/2019

    Standring OJ, Friedberg J, Tripodis Y, Chua AS, Cherry JD, Alvarez VE, Huber BR, Xia W, Mez J, Alosco ML, Nicks R, Mahar I, Pothast MJ, Gardner HM, Meng G, Palmisano JN, Martin BM, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, McKee AC, Stein TD. Contact sport participation and chronic traumatic encephalopathy are associated with altered severity and distribution of cerebral amyloid angiopathy. Acta Neuropathol. 2019 Sep; 138(3):401-413. PMID: 31183671.

    Read at: PubMed
  • Published on 6/1/2019

    Lepage C, Muehlmann M, Tripodis Y, Hufschmidt J, Stamm J, Green K, Wrobel P, Schultz V, Weir I, Alosco ML, Baugh CM, Fritts NG, Martin BM, Chaisson C, Coleman MJ, Lin AP, Pasternak O, Makris N, Stern RA, Shenton ME, Koerte IK. Limbic system structure volumes and associated neurocognitive functioning in former NFL players. Brain Imaging Behav. 2019 Jun; 13(3):725-734. PMID: 29779184.

    Read at: PubMed
  • Published on 5/27/2019

    DeVivo R, Zajac L, Mian A, Cervantes-Arslanian A, Steinberg E, Alosco ML, Mez J, Stern R, Killany R. Differentiating Between Healthy Control Participants and Those with Mild Cognitive Impairment Using Volumetric MRI Data. J Int Neuropsychol Soc. 2019 Sep; 25(8):800-810. PMID: 31130145.

    Read at: PubMed
  • Published on 4/10/2019

    Stern RA, Adler CH, Chen K, Navitsky M, Luo J, Dodick DW, Alosco ML, Tripodis Y, Goradia DD, Martin B, Mastroeni D, Fritts NG, Jarnagin J, Devous MD, Mintun MA, Pontecorvo MJ, Shenton ME, Reiman EM. Tau Positron-Emission Tomography in Former National Football League Players. N Engl J Med. 2019 05 02; 380(18):1716-1725. PMID: 30969506.

    Read at: PubMed
  • Published on 3/27/2019

    Alosco ML, Stern RA. Youth Exposure to Repetitive Head Impacts From Tackle Football and Long-term Neurologic Outcomes: A Review of the Literature, Knowledge Gaps and Future Directions, and Societal and Clinical Implications. Semin Pediatr Neurol. 2019 07; 30:107-116. PMID: 31235012.

    Read at: PubMed
  • Published on 3/8/2019

    Alosco ML, Tripodis Y, Rowland B, Chua AS, Liao H, Martin B, Jarnagin J, Chaisson CE, Pasternak O, Karmacharya S, Koerte IK, Cantu RC, Kowall NW, McKee AC, Shenton ME, Greenwald R, McClean M, Stern RA, Lin A. A magnetic resonance spectroscopy investigation in symptomatic former NFL players. Brain Imaging Behav. 2019 Mar 08. PMID: 30848432.

    Read at: PubMed
  • Published on 3/7/2019

    Sugarman MA, McKee AC, Stein TD, Tripodis Y, Besser LM, Martin B, Palmisano JN, Steinberg EG, O'Connor MK, Au R, McClean M, Killiany R, Mez J, Weiner MW, Kowall NW, Stern RA, Alosco ML. Failure to detect an association between self-reported traumatic brain injury and Alzheimer's disease neuropathology and dementia. Alzheimers Dement. 2019 May; 15(5):686-698. PMID: 30852157.

    Read at: PubMed

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